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Acceleration of Gastric Emptying and Improvement of GERD Outcome After Laparoscopic Sleeve Gastrectomy in Non-diabetic Obese Patients

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Abstract

Purpose

Obesity has become a pandemic nowadays. Bariatric surgery is increasingly performed to manage obesity. Currently, laparoscopic sleeve gastrectomy (LSG) is a widely accepted procedure given its feasibility and efficacy. Previous studies revealed conflicting results regarding the change of gastric emptying following sleeve gastrectomy. The primary aim of the present study is to assess gastric motor function by gastric emptying scintigraphy in a cohort of non-diabetic patients undergoing laparoscopic sleeve gastrectomy (LSG) for treatment of severe obesity.

Methods

This prospective observational study included 100 obese, non-diabetic patients attending the surgery clinic at Cairo University Hospitals and Al Azhar University Hospitals. LSG was performed following a standardized protocol, with no complications observed. All patients had gastric emptying scintigraphy done through a standard semisolid meal (250 kcal), marked with 0.5 mCiTc 99, pre-operatively and 3 months after LSG.

Results

The mean age was 38.71 years (9.2) and males comprised 57% of the cohort. The body mass index, low-density lipoproteins, and glycated hemoglobin declined significantly at 3-month postsurgery. The scintigraphy study revealed a significantly reduced percent retention at equivalent time points 3 months after LSG. In addition, the percent of patients suffering from GERD decreased significantly after LSG.

Conclusion

Gastric emptying becomes faster after LSG in morbidly obese non-diabetic patients. GERD symptoms improve after surgery.

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Author information

Authors and Affiliations

  1. General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt

    Mohamed Abdalla Salman, Hani Maurice Sabri Mikhail, Ahmed Abdelsalam & Ahmed Abdallah

  2. General Surgery Department, Faculty of Medicine, Helwan University, Helwan, Egypt

    Hossam E. Elshafey

  3. Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt

    Tarek Elsayed Abouelregal, Mahmoud Gouda Omar, Hesham Elkassar, Reham Abdelghany Ahmed, Shaimaa Elkholy & Ahmed Abdallah Salman

  4. National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt

    Mohamed Atallah & Hossam El-Din Shaaban

  5. Endemic Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt

    Zeinab Abdellatif

Authors
  1. Mohamed Abdalla Salman
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  2. Hani Maurice Sabri Mikhail
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  14. Ahmed Abdallah Salman
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Corresponding author

Correspondence to Mohamed Abdalla Salman.

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The Ethical Board of the hospitals confirmed the steps of the work, and informed consents were signed by all cases.

Conflict of Interest

The authors declare that they have no conflict of interest.

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Informed consent was obtained from all individual participants included in the study.

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Salman, M.A., Mikhail, H.M.S., Abdelsalam, A. et al. Acceleration of Gastric Emptying and Improvement of GERD Outcome After Laparoscopic Sleeve Gastrectomy in Non-diabetic Obese Patients. OBES SURG 30, 2676–2683 (2020). https://doi.org/10.1007/s11695-020-04547-8

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  • DOI: https://doi.org/10.1007/s11695-020-04547-8

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