Skip to main content

Weight Loss After One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB): Patient-Related Perioperative Predictive Factors



The aim of this study was to find independent perioperative factors predicting unsuccessful weight loss following one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB), a recently developed technique of bariatric surgery.


Using regression analysis, this prospective cohort study assessed the role of demographic and socioeconomic factors, clinical features, body composition, length of biliopancreatic limb (LBL), nutritional habits, comorbidities, and early post-operative weight reduction values, in predicting 1-year weight loss after OAGB-MGB. All patients at the center who underwent laparoscopic OAGB-MGB between October 2010 and May 2017 were included. The dependent variable was the percent of excess weight loss (%EWL) after 12-month follow-up. Weight loss outcome was defined as successful EWL (≥ 50%) or unsuccessful EWL (< 50%).


Follow-up data at 1 year was available for 1309 (77%) patients. Mean EWL and BMI reduction were 81.63% and 16.82 ± 4.37 kg/m2 at 1 year. In addition, 48 (3.7%) patients had unsuccessful weight loss. Pre-operative higher BMI (OR, 1.34; p = 0.001), type 2 diabetes (OR, 4.26; p = 0.039), pre-surgery volume eating habit (OR, 0.12; p = 0.003), weight reduction value in the first month after surgery (OR, 0.80; p = 0.002), and length of biliopancreatic limb (LBL) (OR, 1.05; p = 0.017) were independently associated with unsuccessful weight loss at 1-year follow-up.


OAGB-MGB provides considerable weight loss for most patients. Initial lower BMI, absence of diabetes, being volume eater, and higher first month weight loss are independently associated with successful weight loss after 1 year.

This is a preview of subscription content, access via your institution.


  1. Noria SF, Grantcharov T. Biological effects of bariatric surgery on obesity-related comorbidities. Can J Surg. 2013;56(1):47–57.

    Article  Google Scholar 

  2. Chaim EA, Ramos AC, Cazzo E. Mini-gastric bypass: description of the technique and preliminary results. Arq Bras Cir Dig (São Paulo). 2017;30:264–6.

  3. Mahawar KK, Carr WR, Balupuri S, et al. Controversy surrounding ‘mini’ gastric bypass. Obes Surg. 2014;24(2):324–33.

    Article  Google Scholar 

  4. Mahawar KK, Jennings N, Brown J, et al. “Mini” gastric bypass: systematic review of a controversial procedure. Obes Surg. 2013;23(11):1890–8.

    Article  Google Scholar 

  5. Georgiadou D, Sergentanis TN, Nixon A, et al. Efficacy and safety of laparoscopic mini gastric bypass. A systematic review. Surg Obes Relat Dis. 2014;10(5):984–91.

    Article  Google Scholar 

  6. Campos GM, Rabl C, Mulligan K, et al. Factors associated with weight loss after gastric bypass. Arch Surg. 2008;143(9):877–83. discussion 84

    Article  Google Scholar 

  7. Jambhekar A, Maselli A, Robinson S, et al. Demographics and socioeconomic status as predictors of weight loss after laparoscopic sleeve gastrectomy: a prospective cohort study. Int J Surg. 2018;54(Pt A):163–9.

    Article  Google Scholar 

  8. Melton GB, Steele KE, Schweitzer MA, et al. Suboptimal weight loss after gastric bypass surgery: correlation of demographics, comorbidities, and insurance status with outcomes. J Gastrointest Surg. 2008;12(2):250–5.

    Article  Google Scholar 

  9. Bloomston M, Zervos EE, Camps MA, et al. Outcome following bariatric surgery in super versus morbidly obese patients: does weight matter? Obes Surg. 1997;7(5):414–9.

    Article  CAS  Google Scholar 

  10. Still CD, Wood GC, Chu X, et al. Clinical factors associated with weight loss outcomes after Roux-en-Y gastric bypass surgery. Obesity (Silver Spring). 2014;22(3):888–94.

    Article  Google Scholar 

  11. Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference Statement. Am J Clin Nutr. 1992;55(2 Suppl):615s-9s.

  12. van de Laar AW, van Rijswijk AS, Kakar H, et al. Sensitivity and specificity of 50% excess weight loss (50%EWL) and twelve other bariatric criteria for weight loss success. Obes Surg. 2018;28(8):2297–304.

    Article  Google Scholar 

  13. Gomez-Peralta F, Abreu C, Cruz-Bravo M, et al. Relationship between “a body shape index (ABSI)” and body composition in obese patients with type 2 diabetes. Diabetol Metab Syndr. 2018;10:21.

    Article  Google Scholar 

  14. Peraglie C. Laparoscopic mini-gastric bypass in patients age 60 and older. Surg Endosc. 2016;30(1):38–43.

    Article  Google Scholar 

  15. Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005;15(9):1304–8.

    Article  Google Scholar 

  16. Pazouki A, Esmaeili SK. Excessive weight loss following laparoscopic gastric mini bypass or Roux-en-Y gastric bypass surgery. Int J Clin Med. 2016;07(07):5.

    Article  Google Scholar 

  17. Weiss R, Appelbaum L, Schweiger C, et al. Short-term dynamics and metabolic impact of abdominal fat depots after bariatric surgery. Diabetes Care. 2009;32(10):1910–5.

    Article  Google Scholar 

  18. Pontiroli AE, Frige F, Paganelli M, et al. In morbid obesity, metabolic abnormalities and adhesion molecules correlate with visceral fat, not with subcutaneous fat: effect of weight loss through surgery. Obes Surg. 2009;19(6):745–50.

    Article  Google Scholar 

  19. Shuster A, Patlas M, Pinthus JH, et al. The clinical importance of visceral adiposity: a critical review of methods for visceral adipose tissue analysis. Br J Radiol. 2012;85(1009):1–10.

    Article  CAS  Google Scholar 

  20. Scarpace PJ, Zhang Y. Elevated leptin: consequence or cause of obesity? Front Biosci. 2007;12:3531–44.

    Article  CAS  Google Scholar 

  21. Langenberg C, Shipley MJ, Batty GD, et al. Adult socioeconomic position and the association between height and coronary heart disease mortality: findings from 33 years of follow-up in the Whitehall Study. Am J Public Health. 2005;95(4):628–32.

    Article  Google Scholar 

  22. Sillen L, Andersson E. Patient factors predicting weight loss after Roux-en-Y gastric bypass. J Obes. 2017;2017:3278751.

    Article  Google Scholar 

  23. Palmisano S, Silvestri M, Giuricin M, et al. Preoperative predictive factors of successful weight loss and glycaemic control 1 year after gastric bypass for morbid obesity. Obes Surg. 2015;25(11):2040–6.

    Article  Google Scholar 

  24. Ugale S, Vennapusa A, Katakwar A, et al. Laparoscopic bariatric surgery-current trends and controversies. Ann Laparosc Endosc Surg. 2017;2(10)

  25. Carbajo M, Garcia-Caballero M, Toledano M, et al. One-anastomosis gastric bypass by laparoscopy: results of the first 209 patients. Obes Surg. 2005;15(3):398–404.

    Google Scholar 

  26. Parmar CD, Mahawar KK, Boyle M, et al. Mini Gastric Bypass: first report of 125 consecutive cases from United Kingdom. Clin Obes. 2016;6(1):61–7.

    Article  CAS  Google Scholar 

  27. Boerboom A, Homan J, Aarts E, et al. A long biliopancreatic and short alimentary limb results in more weight loss in revisional RYGB surgery. Outcomes of the randomized controlled ELEGANCE REDO trial. Surg Obes Relat Dis. 2019;15(1):60–9.

    Article  Google Scholar 

  28. Nergaard BJ, Leifsson BG, Hedenbro J, et al. Gastric bypass with long alimentary limb or long pancreato-biliary limb-long-term results on weight loss, resolution of co-morbidities and metabolic parameters. Obes Surg. 2014;24(10):1595–602.

    Article  Google Scholar 

  29. Mor A, Sharp L, Portenier D, et al. Weight loss at first postoperative visit predicts long-term outcome of Roux-en-Y gastric bypass using Duke weight loss surgery chart. Surg Obes Relat Dis. 2012;8(5):556–60.

    Article  Google Scholar 

  30. Colles SL, Dixon JB, O’Brien PE. Grazing and loss of control related to eating: two high-risk factors following bariatric surgery. Obesity (Silver Spring). 2008;16(3):615–22.

    Article  Google Scholar 

  31. Morseth MS, Hanvold SE, Ro O, et al. Self-reported eating disorder symptoms before and after gastric bypass and duodenal switch for super obesity-a 5-year follow-up study. Obes Surg. 2016;26(3):588–94.

    Article  CAS  Google Scholar 

  32. Ma Y, Pagoto SL, Olendzki BC, et al. Predictors of weight status following laparoscopic gastric bypass. Obes Surg. 2006;16(9):1227–31.

    Article  Google Scholar 

Download references


Data were obtained from the National Obesity Surgery Database, Iran. The authors extend their sincere thanks to all participants and the National Obesity Surgery Database team, who prepared us very useful data.

Author information

Authors and Affiliations


Corresponding author

Correspondence to Ali Kabir.

Ethics declarations

This study was approved by Iran University of Medical Science Ethics Committee (Ethic number: IR.IUMS.REC.13970134).

Conflict of Interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Ansar, H., Zamaninour, N., Pazouki, A. et al. Weight Loss After One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB): Patient-Related Perioperative Predictive Factors. OBES SURG 30, 1316–1323 (2020).

Download citation

  • Published:

  • Issue Date:

  • DOI:


  • Excess weight loss, One-anastomosis gastric bypass, Pre-operative, Predictors, Weight reduction