To evaluate the effects of bariatric surgery on patients with type 2 diabetes through comparing Asian and non-Asian populations according to follow-up time.
In this meta-analysis of randomized controlled trials (RCTs), we searched PubMed databases for relevant articles. A meta-analysis was undertaken of 37 eligible RCTs.
Diabetes remission rates among Asian populations were similar to those of non-Asian populations at 1 year (95% confidence interval (CI) 0.519 [0.417, 0.619] vs 0.571 [0.316, 0.794], respectively) but were found to be higher in Asian populations at 2 years compared to non-Asian populations (95% CI 0.672 [0.469, 0.826] vs 0.563 [0.220, 0.855], respectively). Asian populations showed greater reductions in HbA1c (− 3.512 [− 2.726, − 4.299], − 3.001 [− 1.433, − 4.569], and − 3.345 [− 2.267, − 4.423]) than non-Asian populations (− 2.129 [− 1.821, − 2.438], − 2.301 [− 1.881, − 2.722], and − 2.107 [− 1.941, − 2.273]) at 1, 2, and 5 years, respectively. Asian populations also showed greater reductions of fasting plasma glucose than non-Asian populations, and these effects were prominent at 3- and 5-year follow-up (Asian populations, − 83.297 [− 73.264, − 93.331]; non-Asian populations, − 54.288 [− 37.409, − 71.166] at 3 years; Asian populations, − 99.014 [− 82.239, − 115.788]; non-Asian populations, − 45.756 [− 21.892, − 69.621] at 5 years).
Bariatric surgery is more successful in diabetes remission and glucose outcome improvement in Asian populations with type 2 diabetes than in non-Asian populations, even over long-term follow-up periods. Bariatric surgery can be considered an effective treatment option and may present an appropriate opportunity to improve the prognosis for Asian patients with type 2 diabetes.
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Kim, J.H., Pyo, J., Cho, W.J. et al. The Effects of Bariatric Surgery on Type 2 Diabetes in Asian Populations: a Meta-analysis of Randomized Controlled Trials. OBES SURG (2019) doi:10.1007/s11695-019-04257-w
- Bariatric surgery
- Type 2 diabetes