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Impact of Preoperative Anemia on Postoperative Kidney Function Following Laparoscopic Bariatric Surgery

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Abstract

Background

Preoperative anemia is a risk factor for acute kidney failure after high-risk surgeries. We assessed the impact of preoperative anemia on kidney function in an obese Asian population after laparoscopic bariatric surgery.

Methods

Patient characteristics, comorbidities, type of surgery, perioperative profiles, eGFR, and micronutrition were retrospectively reviewed in 341 patients with obesity undergoing bariatric surgery. All patients, who had a preoperative estimated glomerular filtration rates (eGFR) ≥ 90 mL/min/1.73 m2, were followed for 1 year and assigned to one of two groups: anemia or non-anemia group. Preoperative anemia was determined based on hemoglobin concentration.

Results

The Pearson’s correlation coefficient between preoperative body mass index (BMI) and preoperative eGFR of all patients was 0.169 (p = 0.005). Preoperatively, there were no significant differences in age, BMI, and eGFR between the anemia (n = 38) and non-anemia groups (n = 303). Patients in the anemia group had lower hemoglobin concentration at baseline, 1 month, and 12 months after surgery than those in the non-anemia group. Postoperative eGFR levels at 1 month (p = 0.993) and 1 year (p = 0.118) as well as hospital stay (p = 0.941) were comparable between the two groups. However, the percentage weight loss was significantly higher in the non-anemia group than that in the anemia group 1 year after bariatric surgery (30.0 ± 7.3% vs. 27.0 ± 8.1%; p = 0.041).

Conclusions

Preoperative anemia did not negatively impact kidney function following laparoscopic bariatric surgery during the 12-month follow-up. Considering the potential adverse impact of anemia on postoperative weight loss, preoperative correction of anemia may be recommended.

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Author notes

  1. Kuo-Chuan Hung and Shao-Chun Wu contributed equally to this work compared to the first author.

  2. Cheuk-Kwan Sun and Tien-Chou Soong contributed equally compared to the corresponding author.

Authors and Affiliations

  1. Department of Anesthesiology, Chi Mei Medical Center, Tainan, Taiwan

    Kuo-Chuan Hung, Ying-Jen Chang & I-Wen Chen

  2. Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University and College of Medicine, Kaohsiung, Taiwan

    Shao-Chun Wu & Min-Hsien Chiang

  3. Department of Emergency Medicine, E-Da Hospital, School of Medicine for International Students, I-Shou University, Kaohsiung, Taiwan

    Cheuk-Kwan Sun

  4. Weight Loss and Health Management Center, E-Da Dachang Hospital, No. 305, Dachang 1st Rd., Sanmin Dist., Kaohsiung City, 807, Taiwan

    Tien-Chou Soong

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  1. Kuo-Chuan Hung
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Correspondence to Tien-Chou Soong.

Ethics declarations

The protocol of the whole study was reviewed and approved by the institutional research board (IRB) (Approval No. 20181119B). Informed patient consent was waived due to the retrospective nature of this study.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Hung, KC., Wu, SC., Chang, YJ. et al. Impact of Preoperative Anemia on Postoperative Kidney Function Following Laparoscopic Bariatric Surgery. OBES SURG 29, 2527–2534 (2019). https://doi.org/10.1007/s11695-019-03869-6

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  • DOI: https://doi.org/10.1007/s11695-019-03869-6

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