Changes in Energy Expenditure of Patients with Obesity Following Bariatric Surgery: a Systematic Review of Prospective Studies and Meta-analysis
We herein summarize the available literature on the effects of bariatric surgery (BS) on energy expenditure in individuals with obesity. We conducted a systematic literature review, and 35 prospective studies met our inclusion criteria. The findings indicate that BS contributes to increased diet-induced thermogenesis (DIT) and decreased total energy expenditure (TEE) and resting energy expenditure (REE) in patients with obesity. The meta-analysis demonstrated a significant decrease in TEE and REE within 6 months following BS. With the sustained decrease in REE, there was no further decrease in TEE between the 6- and 12-month follow-up. Increased DIT might explain the variance between the patterns of REE and TEE change. The postoperative decrease in REE/FFM and increase in REE/BW were observed. The changes in substrate utilization might be consistent with the change in the respiration quotient postoperatively.
KeywordsBariatric surgery Energy metabolism Diet-induced thermogenesis (DIT) Respiration quotient (RQ) Substrate oxidation
My deepest gratitude goes to Professor Yousheng Li for his constant encouragement and guidance. Without his consistent and illuminating instruction, this study could not have reached its present form.
This study was supported by the Fundamental Research Program Funding of Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine (JYZZ022).
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflicts of interest.
For this type of study (systematic review and meta-analysis), formal consent is not required.
Informed Consent Statement
Informed consent was obtained from all individual participants included in the study.
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