Abstract
Background
Gastroesophageal reflux disease (GERD) occurs de novo or intensifies after sleeve gastrectomy (LSG). Endoscopic radiofrequency (Stretta) is a minimally invasive, effective tool to treat GERD. However, Stretta safety and efficacy are unknown in patients with GERD after LSG. To evaluate the safety and efficacy of Stretta treatment post-LSG GERD, quality of life, and PPI dose up to 6 months.
Methods
A retrospective review of all patients’ data who underwent Stretta procedure in our center. Demographics, pre-Stretta lower esophageal manometry, 24-h pH monitoring, endoscopic and radiological findings, GERD symptoms using Quality of Life (HR-QoL) questionnaire, and PPI doses at 0, 3, and 6 months were reviewed.
Results
Fifteen patients had an initial BMI of 44.4 ± 9 kg/m2. Pre-Stretta BMI was 29.7 ± 6.3 kg/m2 with an EWL% of 44 ± 21.4%. Pre-Stretta endoscopic reflux esophagitis was found in 26.7%, and barium imaging showed severe reflux in 40%. The mean DeMeester score was 27.9 ± 6.7. Hypotensive LES pressure occurred in 93.3% of patients. Patients’ mean HR-QoL scores were 42.7 ± 8.9 pre-Stretta and 41.8 ± 11 at 6 months (P = 0.8). One case (6.7%) was complicated by hematemesis. At 6 months, 66.7% of patients were not satisfied, though the PPI medications were ceased in 20%. Two patients (13.3%) underwent Roux-en-Y gastric bypass at 8 months post-Stretta to relieve symptoms.
Conclusions
Stretta did not improve GERD symptoms in patients post-LSG at short-term follow-up, and about 6.7% complication rate was reported. Patients were not satisfied despite the decrease in PPI dose.
Similar content being viewed by others
References
Felsenreich DM, Kefur R, Schermann M, et al. Reflux, sleeve dilation, and Barrett’s esophagus after laparoscopic sleeve gastrectomy: long-term follow-up. Obes Surg. 2017;27(12):3092–101.
Althuwaini S, Bamehriz F, Aldohayan A, et al. Prevalence and predictors of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Obes Surg. 2017;28:916–22. https://doi.org/10.1007/s11695-017-2971-4.
Rebecchi F, Allaix ME, Patti MG, et al. Gastroesophageal reflux disease and morbid obesity: to sleeve or not to sleeve? World J Gastroenterol. 2017;23(13):2269–75. https://doi.org/10.3748/wjg.v23.i13.2269.
Hawasli A, Tarakji M, Tarboush M. Laparoscopic management of severe reflux after sleeve gastrectomy using the LINX® system: technique and one year follow up case report. Int J Surg Case Rep. 2017;30:148–51. https://doi.org/10.1016/j.ijscr.2016.11.050.
Desart K, Rossidis G, Michel M, et al. Gastroesophageal reflux management with the LINX® system for gastroesophageal reflux disease following laparoscopic sleeve gastrectomy. J Gastrointest Surg. 2015;19(10):1782–6. https://doi.org/10.1007/s11605-015-2887-z.
Mattar SG, Qureshi F, Taylor D, et al. Treatment of refractory gastroesophageal reflux disease with radiofrequency energy (Stretta) in patients after Roux-en-Y gastric bypass. Surg Endosc. 2006;20(6):850–4. Epub 2006 May 12
Elhag W, El Ansari W, Abdulrazzaq S, et al. Evolution of 29 anthropometric, nutritional, and cardiometabolic parameters among morbidly obese adolescents 2 years post sleeve gastrectomy. Obes Surg. 2017;28:474–82. https://doi.org/10.1007/s11695-017-2868-2.
Triadafilopoulos G, DiBaise JK, Nostrant TT, et al. The Stretta procedure for the treatment of GERD: 6 and 12 month follow-up of the U.S. open label trial. Gastrointest Endosc. 2002;55(2):149–56.
Rebecchi F, Allaix ME, Giaccone C, et al. Gastroesophageal reflux disease and laparoscopic sleeve gastrectomy: a physiopathologic evaluation. Ann Surg. 2014;260:909–14. discussion 914-905
Soricelli E, Iossa A, Casella G, et al. Sleeve gastrectomy and crural repair in obese patients with gastroesophageal reflux disease and/or hiatal hernia. Surg Obes Relat Dis. 2013;9:356–61.
DuPree CE, Blair K, Steele SR, et al. Laparoscopic sleeve gastrectomy in patients with preexisting gastroesophageal reflux disease A National Analysis. JAMA Surg. 2014;149(4):328–34. https://doi.org/10.1001/jamasurg.2013.4323.
Santonicola A, Angrisani L, Cutolo P, et al. The effect of laparoscopic sleeve gastrectomy with or without hiatal hernia repair on gastroesophageal reflux disease in obese patients. Surg Obes Relat Dis. 2014;10(2):250–5.
Stenard F, Iannelli A. Laparoscopic sleeve gastrectomy and gastroesophageal reflux. World J Gastroenterol. 2015;21(36):10348–57. https://doi.org/10.3748/wjg.v21.i36.10348.
Luigi A (Ed.) Bariatric and metabolic surgery indications, complications and revisional procedures. eBook ISBN: 978–88–470-3944-5. https://doi.org/10.1007/978-88-470-3944-5
Daes J, Jimenez ME, Said N, et al. Improvement of gastroesophageal reflux symptoms after standardized laparoscopic sleeve gastrectomy. Obes Surg. 2014;24:536–40. https://doi.org/10.1007/s11695-013-1117-6.
Bashashati M, Hejazi RA, Andrews CN, et al. Gastroesophageal reflux symptoms not responding to proton pump inhibitor: GERD, NERD, NARD, esophageal hypersensitivity or dyspepsia? Can J Gastroenterol Hepatol. 2014;28(6):335–41.
Liakakos T, Karamanolis G, Patapis P, et al. Gastroesophageal reflux disease: medical or surgical treatment? Gastroenterol Res Practice. 2009. https://doi.org/10.1155/2009/371580.
Liang WT, Wu JM, Wang F, et al. Stretta radiofrequency for gastroesophageal reflux disease-related respiratory symptoms: a prospective 5-year study. Minerva Chir. 2014;69(5):293–9.
Fass R, Cahn F, Scotti DJ, et al. Systematic review and meta-analysis of controlled and prospective cohort efficacy studies of endoscopic radiofrequency for treatment of gastroesophageal reflux disease. Surg Endosc. 2017;31(12):4865–82.
Reimer C. Safety of long-term PPI therapy. Best Practice Res Clin Gastroenterol. 2013;27:443–54.
Acknowledgements
We would like to acknowledge Mr. Arnel Alviz (system analyst, Hamad Medical Corporation-Qatar) for his contribution in data collection and statistical analysis.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
The authors declare that they have no conflict of interest.
Ethical Approval
The current study was conducted after the research protocol was approved by the institutional review board of the Medical Research Centre at Hamad Medical Corporation (17201/17). For this type of study, formal consent is not required.
Rights and permissions
About this article
Cite this article
Khidir, N., Angrisani, L., Al-Qahtani, J. et al. Initial Experience of Endoscopic Radiofrequency Waves Delivery to the Lower Esophageal Sphincter (Stretta Procedure) on Symptomatic Gastroesophageal Reflux Disease Post-Sleeve Gastrectomy. OBES SURG 28, 3125–3130 (2018). https://doi.org/10.1007/s11695-018-3333-6
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11695-018-3333-6