Abstract
Background
Recent Research evidences from across the world indicate the usefulness of bariatric surgery in improving the immunological co-morbidities in patients with morbid obesity.
Aim
The aim of the study was to evaluate the outcome from bariatric surgery in patients presenting with diabetes mellitus and or morbid obesity with immunological co-morbidities.
Methods
It was a retrospective cross-sectional study. Study included patients with morbid obesity with immunological co-morbidities, and additional co- morbidity of type 2 diabetes mellitus in about one third of the cases, who had undergone bariatric surgery during the period 2014–2016 at our center. Patient demographics, preoperative data, and follow-up data were collected and analyzed. Patients were followed for assessing the outcome in terms of BMI and dependency on medications to evaluate the effectiveness of the procedure.
Results
The study included 23 patients (52% female and 48% male). Bariatric surgery was effective in all the patients (except one) in weight reduction. Significant reduction in weight and BMI was observed (p < 0.05). The recent follow-up of these patients showed that the mean BMI of the study group decreased significantly, 34.4% patients had attained normal BMI ≤ 25 kg/m2. Three-month follow-up indicated that 55.56% were not dependent on medications. At 1-year follow-up, 94.4% patients were without any dependency on immunosuppressive medications. Complications included a reversal of surgery and a case of mortality.
Conclusion
The results of our study have shown that immune-compromised patients can undergo bariatric surgery with good weight loss results and improvement in co-morbidities.
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References
Romero-Talamás H, Aminian A, Corcelles R, et al. Psoriasis improvement after bariatric surgery. Surg Obes Relat Dis. 2014;10(6):1155–9.
Debbaneh M, Millsop JW, Bhatia BK, et al. Diet and psoriasis: part I. Impact of weight loss interventions. J Am Acad Dermatol. 2014;71(1):133–40.
Klebanoff MJ, Corey KE, Chhatwal J, et al. Bariatric surgery for nonalcoholic steatohepatitis: a clinical and cost-effectiveness analysis. Hepatology. 2017;65(4):1156–64.
Raquel G-H, Neil P, Mario M, et al. Patton Kristin, and Elli Enrique F. Bariatric Surgical Practice and Patient Care. 2016;11(1):6–10.
Park S, Kim YJ, Choi CY, et al., Bariatric surgery can reduce albuminuria in patients with severe obesity and normal kidney function by reducing systemic inflammation. Obes Surg. 2017.
Tsamalaidze L, Elli EF. Bariatric surgery is gaining ground as treatment of obesity after heart transplantation: report of two cases. Obes Surg. 2017; https://doi.org/10.1007/s11695-017-2908-y.
Gagne DJ, Papasavas PK, Dovec EA, et al. Effect of immunosuppression on patients undergoing bariatric surgery. Surg Obes Relat Dis. 2009;5(3):339–45.
Fazylov R, Soto E, Merola S. Laparoscopic gastric bypass surgery in human immunodeficiency virus-infected patients. Surg Obes Relat Dis. 2007;3:637–9.
Hossler EW, Maroon MS, Moward CM. Gastric bypass surgery improves psoriasis. J Am Acad Dermatol. 2011;65(1):198–200.
Sako EY, Famenini S, Wu JJ. Bariatric surgery and psoriasis. J Am Acad Dermatol. 2014;70(4):774–9.
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The authors declare that they have no conflict of interest.
Informed Consent
Informed consent was obtained from all individual participants included in the study.
Statement of Human and Animal Rights
This study was performed in accordance with the principles of declaration of Helsinki and was approved by the Institutional ethical committee.
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Khaitan, M., Hegde, A. & Rekha, P.D. Bariatric Surgery in Immunocompromised Patients: Outcomes from One Year Follow-up. OBES SURG 28, 2811–2814 (2018). https://doi.org/10.1007/s11695-018-3251-7
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DOI: https://doi.org/10.1007/s11695-018-3251-7