Skip to main content
Log in

Resolution of Symptomatic Obstructive Sleep Apnea Not Impacted by Preoperative Body Mass Index, Choice of Operation Between Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Surgery, or Severity

  • Original Contributions
  • Published:
Obesity Surgery Aims and scope Submit manuscript

Abstract

Background

Obstructive sleep apnea (OSA) is a serious obesity-associated disorder that causes significant short- and long-term medical consequences.

Objective

The objective of this study is to compare the 6-month and 1-year postoperative symptomatic OSA remission rates of patients undergoing bariatric surgery based on their preoperative body mass index (BMI) stratification, type of bariatric operation—sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB)—and OSA severity.

Methods

We retrospectively analyzed 297 obese patients with a diagnosis of OSA who had undergone either SG or RYGB between 2011 and 2015.

Results

The overall 6-month symptomatic OSA remission rate for patients (n = 255) was 74.5%. At 6 months, patients with a preoperative BMI of 30–34.9 kg/m2 (class I), 35–39.9 kg/m2 (class II), and 40+ kg/m2 (class III) had 100, 70.0, and 75.0% (p = 0.2164) remission rates, respectively. The 6-month remission rates for SG and RYGB were 75.3 and 70.8% (p = 0.5165), respectively. The overall 1-year symptomatic OSA remission rate for patients (n = 162) was 87.1%. At 1 year, class I, II, and III patients had 100, 85.7, and 87.5% (p = 0.5740) remission rates, respectively. The 1-year remission rates for SG and RYGB were 89.2 and 81.2% (p = 0.2189), respectively. A sub-analysis (n = 69) based on preoperative OSA severity levels did not affect the remission outcome at either the 6-month (p = 0.3670) or 1-year (p = 0.3004) follow-up.

Conclusion

Most obese patients experience symptomatic remission of their OSA after bariatric surgery, regardless of their preoperative BMI, choice of operation, or OSA severity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Schwartz AR, Patil SP, Laffan AM, et al. Obesity and obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):185–92. https://doi.org/10.1513/pats.200708-137MG.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Romero-Corral A, Caples SM, Lopez-Jimenez F, et al. Interactions between obesity and obstructive sleep apnea. Chest. 2010;137(3):711–9. https://doi.org/10.1378/chest.09-0360.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  3. Dempsey JA, Veasey SC, Morgan BJ, et al. Pathophysiology of sleep apnea. Physiol Rev. 2010;90(1):47–112. https://doi.org/10.1152/physrev.00043.2008.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  4. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002;165(9):1217–39. https://doi.org/10.1164/rccm.2109080.

    Article  PubMed  Google Scholar 

  5. Punjabi NM. The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):136–43. https://doi.org/10.1513/pats.200709-155MG.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Salome CM, King GG, Berend N. Physiology of obesity and effects on lung function. J Appl Physiol. 2010;108(1):206–11. https://doi.org/10.1152/japplphysiol.00694.2009.

    Article  PubMed  Google Scholar 

  7. Haines KL, Nelson LG, Gonzalez R, et al. Objective evidence that bariatric surgery improves obesity-related obstructive sleep apnea. Surgery. 2007;141(3):354–8. https://doi.org/10.1016/j.surg.2006.08.012.

    Article  PubMed  Google Scholar 

  8. Peppard PE, Young T, Palta M, et al. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA. 2000;284(23):3015–21. https://doi.org/10.1001/jama.284.23.3015.

    Article  PubMed  CAS  Google Scholar 

  9. Carvalho B, Hsia J, Capasso R. Surgical therapy of obstructive sleep apnea: a review. Neurotherapeutics. 2012;9(4):710–6. https://doi.org/10.1007/s13311-012-0141-x.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Motamedi KK, McClary AC, Amedee RG. Obstructive sleep apnea: a growing problem. Ochsner J. 2009;9(3):149–53.

    PubMed  PubMed Central  Google Scholar 

  11. Brethauer S, Eisenberg D, Kim J. Standardized outcomes reporting in metabolic and bariatric surgery. American Society for Metabolic and Bariatric Surgery. https://asmbs.org/resources/standardized-outcomes-reporting-in-metabolic-and-bariatric-surgery. 2015. Accessed September11, 2017.

  12. Won L, Swamy N, Meir K, et al. Epidemiology of obstructive sleep apnea: a population-based perspective. Expert Rev Respir Med. 2008;2(3):349–64.

    Article  Google Scholar 

  13. Young T, Finn L, Peppard PE, et al. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin Sleep Cohort. Sleep. 2008;31(8):1071–8.

    PubMed  PubMed Central  Google Scholar 

  14. Park JG, Ramar K, Olson EJ. Updates on definition, consequences, and management of obstructive sleep apnea. Mayo Clin Proc. 2011;86(6):549–55. https://doi.org/10.4065/mcp.2010.0810.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Bounhoure J-P, Galinier M, Didier A, et al. Sleep apnea syndromes and cardiovascular disease. Bull Acad Natl Med. 2005;189(3):445–59.

    PubMed  Google Scholar 

  16. Calvin AD, Albuquerque FN, Lopez-Jimenez F, et al. Obstructive sleep apnea, inflammation, and the metabolic syndrome. Metab Syndr Relat Disord. 2009;7(4):271–7. https://doi.org/10.1089/met.2008.0093.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724–37. https://doi.org/10.1001/jama.292.14.1724.

    Article  PubMed  CAS  Google Scholar 

  18. Zhang N, Maffei A, Cerabona T, et al. Reduction in obesity-related comorbidities: is gastric bypass better than sleeve gastrectomy? Surg Endosc. 2013;27(4):1273–80. https://doi.org/10.1007/s00464-012-2595-7.

    Article  PubMed  Google Scholar 

  19. Li J, Lai D, Wu D. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy to treat morbid obesity-related comorbidities: a systematic review and meta-analysis. Obes Surg. 2016;26(2):429–42. https://doi.org/10.1007/s11695-015-1996-9.

    Article  PubMed  Google Scholar 

  20. Peterli R, Borbély Y, Kern B, et al. Early results of the Swiss Multicentre Bypass or Sleeve Study (SM-BOSS). Ann Surg. 2013;258(5):690–5. https://doi.org/10.1097/SLA.0b013e3182a67426.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Nagendran M, Carlin AM, Bacal D, et al. Self-reported remission of obstructive sleep apnea following bariatric surgery: cohort study. Surg Obes Relat Dis. 2015;11(3):697–703. https://doi.org/10.1016/j.soard.2014.10.011.

    Article  PubMed  Google Scholar 

  22. Balachandran JS, Masa JF, Mokhlesi B. Obesity hypoventilation syndrome epidemiology and diagnosis. Sleep Med Clin. 2014;9(3):341–7. https://doi.org/10.1016/j.jsmc.2014.05.007.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Macavei VM, Spurling KJ, Loft J, et al. Diagnostic predictors of obesity-hypoventilation syndrome in patients suspected of having sleep disordered breathing. J Clin Sleep Med. 2013;9(9):879–84. https://doi.org/10.5664/jcsm.2986.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Lettieri CJ, Eliasson AH, Greenburg DL. Persistence of obstructive sleep apnea after surgical weight loss. J Clin Sleep Med. 2008;4(4):333–8.

    PubMed  PubMed Central  Google Scholar 

  25. Nagappa M, Liao P, Wong J, et al. Validation of the STOP-Bang questionnaire as a screening tool for obstructive sleep apnea among different populations: a systematic review and meta-analysis. PLoS One. 2015;10(12):e0143697. https://doi.org/10.1371/journal.pone.0143697.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gustavo Fernandez-Ranvier.

Ethics declarations

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hariri, K., Kini, S.U., Herron, D.M. et al. Resolution of Symptomatic Obstructive Sleep Apnea Not Impacted by Preoperative Body Mass Index, Choice of Operation Between Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Surgery, or Severity. OBES SURG 28, 1402–1407 (2018). https://doi.org/10.1007/s11695-017-3042-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11695-017-3042-6

Keywords

Navigation