Problematic Alcohol Use and Associated Characteristics Following Bariatric Surgery
- 333 Downloads
Evidence suggests that a significant minority of individuals who undergo Roux-en-Y gastric bypass (RYGB) experience problematic alcohol and substance use following surgery. However, little research has examined characteristics, drinking patterns, and possible risk factors within this population. To provide descriptive information of a sample of adults with self-identified alcohol use problems following bariatric surgery, this study examined (1) alcohol and substance use symptoms using standardized assessments, (2) current and past psychiatric comorbidity, (3) subjective changes in alcohol sensitivity following surgery, and (4) specific patterns of alcohol use prior to and following bariatric surgery.
Materials and Methods
Adult participants (N = 26) completed a series of structured diagnostic interviews and self-report assessments (e.g., Alcohol Use Disorders Identification Test [AUDIT], Michigan Alcohol Screening Test [MAST], Drug Abuse Screening Test [DAST]) by telephone 1 to 4 years following a RYGB or sleeve gastrectomy.
All participants met objective criteria for current problematic alcohol use based on AUDIT and MAST cutoff scores, reported increased subjective sensitivity to alcohol following surgery, and evidenced significant current and past psychiatric comorbidities, most notably previous major depression (45.5%). Approximately one third of participants evidenced new-onset Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) alcohol use or dependence following surgery. Preoperative drinking frequencies and quantities were similar to those reported during the period of the heaviest postoperative alcohol use.
Findings have implications for pre- and postoperative prevention and intervention efforts. Additional research is needed to further elucidate risk factors for problematic alcohol use following bariatric surgery.
KeywordsPostoperative alcohol problems Alcohol use Substance use Comorbidity Psychopathology
Compliance with Ethical Standards
Conflicts of Interest
Authors K.E.S., S.G.E., K.J.S., L.G., K.G., A.K., and J.E.M. have no conflicts of interest to disclose. The research was supported by NIMH T32MH082761 (Author K.E.S.). K.J.S. was also supported by the following grants: NIH (1R01DK112585, 3R01DK112585-01S1, 1R01AA022336, 3R01AA022336-01A1S1), Shire Pharmaceuticals, and Sanford Profile.
Informed consent was obtained from all individual participants included in the study.
Human and Animal Rights
All procedures performed were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
- 3.King WC, Chen JY, Courcoulas AP, Dakin GF, Engel SG, Flum DR, Hinojosa MW, Kalarchian MA, Mattar SG, Mitchell JE, Pomp A. Alcohol and other substance use after bariatric surgery: prospective evidence from a US multicenter cohort study. Surg Obes Relat Dis. 2017;(Epub ahead of print):1392–1402.Google Scholar
- 10.Blackburn AN, Hajnal A, Leggio L. The gut in the brain: the effects of bariatric surgery on alcohol consumption. Addict Biol. 2016;(Epub ahead of print):1–11.Google Scholar
- 14.Sheehan D, Janavs J, Baker R, et al. MINI International Neuropsychiatric Interview (English version 5.0. 0) for DSM-IV. Tampa: University of South Florida; 2006.Google Scholar
- 15.First MB, Spitzer RL, Miriam G, Williams JBW. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition. SCID-I/NP) New York: Biometrics Research, New York State Psychiatric Institute; 2002.Google Scholar
- 21.Dawe S, Mattick RP. Review of diagnostic screening instruments for alcohol and other drug use and other psychiatric disorders. AGPS; 1997.Google Scholar