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Glucose Variability After Bariatric Surgery: Is Prediction of Diabetes Remission Possible?

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Abstract

We aimed to corroborate glycemic control after bariatric surgery (BS) using continuous glucose monitoring (CGM) and analyze if data could predict long-term outcome. We evaluated 24 of our patients with type 2 diabetes who underwent BS (12 Roux-en-Y gastric bypass, RYGB, and 12 single-anastomosis duodeno-ileal bypass with sleeve gastrectomy, SADI-S) and who were in remission after 18–24 months’ follow-up. At this time, a CGM device was placed for 7 days. Patients were reevaluated thereafter for at least 5 years. Glucose variability (GV) was lower in patients after SADI-S and in the 18 patients who were still in remission after 5 years, and provided more information on long-term status than classical diabetes-related characteristics.

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Authors and Affiliations

  1. Department of Endocrinology and Nutrition, Hospital Universitario La Princesa, Instituto de Investigación Princesa, Universidad Autónoma de Madrid, C/ Diego de León 62, 28006, Madrid, Spain

    Ana M. Ramos-Leví

  2. Department of Surgery, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Facultad de Medicina, Complutense University, C/ Prof. Martin Lagos s/n, 28040, Madrid, Spain

    Andrés Sánchez-Pernaute & Antonio J. Torres

  3. Department of Endocrinology and Nutrition, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Facultad de Medicina, Complutense University, C/ Prof. Martin Lagos s/n, 28040, Madrid, Spain

    Clara Marcuello, Mercedes Galindo, Alfonso L. Calle-Pascual & Miguel A. Rubio

  4. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain

    Alfonso L. Calle-Pascual

Authors
  1. Ana M. Ramos-Leví
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  2. Andrés Sánchez-Pernaute
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  3. Clara Marcuello
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  4. Mercedes Galindo
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  5. Alfonso L. Calle-Pascual
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  6. Antonio J. Torres
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  7. Miguel A. Rubio
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Corresponding author

Correspondence to Ana M. Ramos-Leví.

Ethics declarations

The study was approved by the Ethics Committee of the Hospital Clinico San Carlos and was in compliance with the Helsinki Declaration.

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The authors declare that they have no conflict of interest.

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Ramos-Leví, A.M., Sánchez-Pernaute, A., Marcuello, C. et al. Glucose Variability After Bariatric Surgery: Is Prediction of Diabetes Remission Possible?. OBES SURG 27, 3341–3343 (2017). https://doi.org/10.1007/s11695-017-2960-7

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  • DOI: https://doi.org/10.1007/s11695-017-2960-7

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