Skip to main content
Log in

Is Concomitant Cholecystectomy Necessary for Asymptomatic Cholelithiasis During Laparoscopic Sleeve Gastrectomy?

  • Original Contributions
  • Published:
Obesity Surgery Aims and scope Submit manuscript

Abstract

Background

There is not any consensus on concomitant cholecystectomy for asymptomatic gallbladder stones during laparoscopic sleeve gastrectomy (LSG). The aim of this study was to evaluate the surveillance results of the LSG patients who have asymptomatic gallbladder stones and did not undergo cholecystectomy.

Methods

Patients who underwent laparoscopic sleeve gastrectomy with preoperatively detected gallbladder stones and completed at least 6 months follow-up were included in the study. Concomitant cholecystectomy was performed for symptomatic patients while it was not performed for asymptomatic subjects. At the end of the follow-up time, symptoms and signs related to gallbladder disease were recorded. Clinical and demographic characteristics were compared between symptomatic and asymptomatic patients.

Results

Between February 2012 and October 2016, 312 laparoscopic sleeve gastrectomies were performed. Among the patients, 24 were regarded as asymptomatic cholelithiasis, and cholecystectomy was not performed. The mean follow-up period was 27 (6–58) months. The mean preoperative BMI was 50.0 ± 7.6 kg/m2, and at the end of the follow-up time, it decreased to 35.6 ± 8.8 kg/m2. Five (20.8%) patients experienced biliary colic. Acute cholecystitis or obstructive jaundice was not observed in any of the patients. Characteristics of patients who developed symptomatic gallbladder disease (n = 5) were not significantly different from those of patients who remained asymptomatic (n = 19).

Conclusions

The risk of becoming symptomatic for asymptomatic cholelithiasis is very close to the healthy population after sleeve gastrectomy. Although further studies with a high number of cases are needed, we suggest only observation for asymptomatic gallbladder stones in patients who will undergo sleeve gastrectomy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Shiffman ML, Sugerman HJ, Kellum JM, et al. Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol. 1991;86(8):1000–5.

    CAS  PubMed  Google Scholar 

  2. Torgerson JS, Lindroos AK, Näslund I, et al. Gallstones, gallbladder disease, and pancreatitis: cross-sectional and 2-year data from the Swedish Obese Subjects (SOS) and SOS reference studies. Am J Gastroenterol. 2003;98(5):1032–41.

    PubMed  Google Scholar 

  3. Fobi M, Lee H, Igwe D, et al. Prophylactic cholecystectomy with gastric bypass operation: incidence of gallbladder disease. Obes Surg. 2002;12:350–3.

    Article  PubMed  Google Scholar 

  4. Aidonopoulos AP, Papavramidis ST, Zaraboukas HHW, et al. Gallbladder findings after cholecystectomy in morbidly obese patients. Obes Surg. 1994;4:8–12.

    Article  CAS  PubMed  Google Scholar 

  5. Amstutz S, Michel JM, Kopp S, et al. Potential benefits of prophylactic cholecystectomy in patients undergoing bariatric bypass surgery. Obes Surg. 2015;25(11):2054–60.

    Article  PubMed  Google Scholar 

  6. Warschkow R, Tarantino I, Ukegjini K, et al. Concomitant cholecystectomy during laparoscopic Roux-en-Y gastric bypass in obese patients is not justified: a meta-analysis. Obes Surg. 2013;23(3):397–407.

    Article  PubMed  Google Scholar 

  7. Coupaye M, Castel B, Sami O, et al. Comparison of the incidence of cholelithiasis after sleeve gastrectomy and Roux-en-Y gastric bypass in obese patients: a prospective study. Surg Obes Relat Dis. 2015;11(4):779–84.

    Article  PubMed  Google Scholar 

  8. Li VK, Pulido N, Fajnwaks P, et al. Predictors of gallstone formation after bariatric surgery: a multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy. Surg Endosc. 2009;23(7):1640–4.

    Article  PubMed  Google Scholar 

  9. Dakour Aridi H, Sultanem S, Abtar H, et al. Management of gallbladder disease after sleeve gastrectomy in a selected Lebanese population. Surg Obes Relat Dis. 2016;12(7):1300–4.

    Article  PubMed  Google Scholar 

  10. Hasan MY, Lomanto D, Loh LL, So JB, Shabbir A. 2017. Gallstone disease after laparoscopic sleeve gastrectomy in an Asian population—what proportion of gallstones actually becomes symptomatic? Obes Surg.

  11. Gastrointestinal surgery for severe obesity. NIH Consensus Statement. 1991;9(1):1–20.

  12. Tucker ON, Fajnwaks P, Szomstein S, et al. Is concomitant cholecystectomy necessary in obese patients undergoing laparoscopic gastric bypass surgery? Surg Endosc. 2008;22(11):2450–4.

    Article  CAS  PubMed  Google Scholar 

  13. Li VK, Pulido N, Martinez-Suartez P, et al. Symptomatic gallstones after sleeve gastrectomy. Surg Endosc. 2009;23(11):2488–92.

    Article  PubMed  Google Scholar 

  14. Moon RC, Teixeira AF, DuCoin C, et al. Comparison of cholecystectomy cases after Roux-en-Y gastric bypass, sleeve gastrectomy, and gastric banding. Surg Obes Relat Dis. 2014;10(1):64–8.

    Article  PubMed  Google Scholar 

  15. Tsirline VB, Keilani ZM, El Djouzi S, et al. How frequently and when do patients undergo cholecystectomy after bariatric surgery? Surg Obes Relat Dis. 2014;10(2):313–21.

    Article  PubMed  Google Scholar 

  16. Malin SK, Kashyap SR. Differences in weight loss and gut hormones: Roux-en-Y gastric bypass and sleeve gastrectomy. Surgery Curr Obes Rep. 2015;4:279–28.

    Article  PubMed  Google Scholar 

  17. Belgaumkar AP, Vincent RP, Carswell KA, et al. Changes in bile acid profile after laparoscopic sleeve gastrectomy are associated with improvements in metabolic profile and fatty liver disease. Obes Surg. 2016;26(6):1195–202.

    Article  PubMed  Google Scholar 

  18. Raziel A, Sakran N, Szold A, et al. Concomitant cholecystectomy during laparoscopic sleeve gastrectomy. Surg Endosc. 2015;29(9):2789–93.

    Article  PubMed  Google Scholar 

  19. Sioka E, Zacharoulis D, Zachari E, et al. Complicated gallstones after laparoscopic sleeve gastrectomy. J Obes. 2014;2014:468203.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Behari A, Kapoo VK. Asymptomatic gallstones (AsGS)—to treat or not to? Indian J Surg. 2012;74(1):4–12.

    Article  PubMed  Google Scholar 

  21. Conley A, Tarboush M, Manatsathit W, et al. Do gallstones found before sleeve gastrectomy behave the same as those formed after surgery due to weight loss? Am J Surg. 2016;212(5):931–4. doi:10.1016/j.amjsurg.2016.01.039.

    Article  PubMed  Google Scholar 

  22. Morais M, Faria G, Preto J, et al. Gallstones and bariatric surgery: to treat or not to treat? World J Surg. 2016;40(12):2904–10.

    Article  PubMed  Google Scholar 

  23. Johna S. Gallstones and bariatric surgery: to treat or not to treat? Editorial Perspective World J Surg. 2016;40(12):2911–2.

    Google Scholar 

  24. Lambert DM, Marceau S, Forse RA. Intra-abdominal pressure in the morbidly obese. Obes Surg. 2005;15(9):1225–32.

    Article  PubMed  Google Scholar 

  25. Pavlidis TE, Marakis GN, Ballas K, et al. Risk factors influencing conversion of laparoscopic to open cholecystectomy. J Laparoendosc Adv Surg Tech A. 2007;17(4):414–8.

    Article  PubMed  Google Scholar 

  26. Aziz H, Pandit V, Joseph B, et al. Age and obesity are independent predictors of bile duct injuries in patients undergoing laparoscopic cholecystectomy. World J Surg. 2015;39(7):1804–8.

    Article  PubMed  Google Scholar 

  27. Siavash Raigani MD, Amy G, Fiedler MD, et al. The management of asymptomatic (silent) gallstones. In: Cameron A, editor. Current surgical therapy. twelfth ed. Philadelphia, PA: Elsevier; 2017. p. 427–9.

    Google Scholar 

Download references

Acknowledgements

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Samet Yardimci.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institution and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained for all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yardimci, S., Coskun, M., Demircioglu, S. et al. Is Concomitant Cholecystectomy Necessary for Asymptomatic Cholelithiasis During Laparoscopic Sleeve Gastrectomy?. OBES SURG 28, 469–473 (2018). https://doi.org/10.1007/s11695-017-2867-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11695-017-2867-3

Keywords

Navigation