Skip to main content
Log in

Effect of Protein Intake on the Protein Status and Lean Mass of Post-Bariatric Surgery Patients: a Systematic Review

  • Review Article
  • Published:
Obesity Surgery Aims and scope Submit manuscript

Abstract

Background

Post-bariatric surgery may compromise nutritional status due to energy and protein intake restriction.

Methods

Systematic review was performed to synthesize evidence on the amount of protein intake and its association with lean mass and serum proteins during at least 6 months following Roux-en-Y gastric bypass or sleeve gastrectomy.

Results

Twelve studies (n = 739) were identified in the search. Protein intake below 60 g/day and significant lean mass loss were observed in majority of these studies. Of the four studies that measured association between protein intake and lean mass retention, only two supported this hypothesis.

Conclusion

There is insufficient evidence of the effect of dietary protein on serum protein levels. Further studies are needed to better estimate the protein intake that supports a healthy nutritional status in this population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Puzziferri N, Roshek TB, Mayo HG, et al. Long-term follow-up after bariatric surgery: a systematic review. JAMA. 2014;312(9):934–42.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery worldwide 2013. Obes Surg. 2015;25(10):1822–32.

    Article  CAS  PubMed  Google Scholar 

  3. Raftopoulos I, Bernstein B, O’Hara K, et al. Protein intake compliance of morbidly obese patients undergoing bariatric surgery and its effect on weight loss and biochemical parameters. Surg Obes Relat Dis. 2011;7(6):733–42.

    Article  PubMed  Google Scholar 

  4. Verger EO, Aron-Wisnewsky J, Dao MC, et al. Micronutrient and protein deficiencies after gastric bypass and sleeve gastrectomy: a 1-year follow-up. Obes Surg. 2015;26(4):785–96.

    Article  Google Scholar 

  5. Giusti V, Theytaz F, Di Vetta V, et al. Energy and macronutrient intake after gastric bypass for morbid obesity: a 3-y observational study focused on protein consumption. Am J Clin Nutr. 2016;103(1):18–24.

    Article  CAS  PubMed  Google Scholar 

  6. Shenkin A. Serum prealbumin: is it a marker of nutritional status or of risk of malnutrition? Clin Chem. 2006;52(12):2177–9.

    Article  CAS  PubMed  Google Scholar 

  7. Faria SL, Faria OP, Buffington C, et al. Dietary protein intake and bariatric surgery patients: a review. Obes Surg. 2011;21(11):1798–805.

    Article  PubMed  Google Scholar 

  8. Andreu A, Moize V, Rodriguez L, et al. Protein intake, body composition, and protein status following bariatric surgery. Obes Surg. 2010;20(11):1509–15.

    Article  PubMed  Google Scholar 

  9. Mechanick JI, Youdim A, Jones DB, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, the Obesity Society, and American Society for Metabolic & bariatric surgery. Endocr Pract. 2013;19(2):337–72.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.

    Article  PubMed  PubMed Central  Google Scholar 

  11. The Joanna Briggs Intitute. Joanna Briggs Institute Reviewers’ Manual: 2014 edition [Updated 2014]. http://joannabriggs.org/assets/docs/sumari/ReviewersManual-2014-Summary-of-Findings-Tables.pdf. Accessed April 20, 2016.

  12. Huguet A, Hayden JA, Stinson J, et al. Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework. Syst Rev. 2013;2:71.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Bavaresco M, Paganini S, Lima TP, et al. Nutritional course of patients submitted to bariatric surgery. Obes Surg. 2010;20(6):716–21.

    Article  PubMed  Google Scholar 

  14. Gobato RC, Chaves DFS, Chaim EA. Micronutrient and physiologic parameters before and 6 months after RYGB. Surg Obes Relat Dis. 2014;10(5):944–51.

    Article  PubMed  Google Scholar 

  15. Nicoletti CF, Junqueira-Franco MVM, dos Santos JE, et al. Protein and amino acid status before and after bariatric surgery: a 12-month follow-up study. Surg Obes Relat Dis. 2013;9(6):1008–12.

    Article  PubMed  Google Scholar 

  16. Coupaye M, Riviere P, Breuil MC, et al. Comparison of nutritional status during the first year after sleeve gastrectomy and roux-en-Y gastric bypass. Obes Surg. 2014;24(2):276–83.

    Article  PubMed  Google Scholar 

  17. Moize V, Andreu A, Rodriguez L, et al. Protein intake and lean tissue mass retention following bariatric surgery. Clin Nutr. 2013;32(4):550–5.

    Article  CAS  PubMed  Google Scholar 

  18. Carrasco F, Papapietro K, Csendes A, et al. Changes in resting energy expenditure and body composition after weight loss following roux-en-Y gastric bypass. Obes Surg. 2007;17(7):608–16.

    Article  PubMed  Google Scholar 

  19. Schollenberger AE, Karschin J, Meile T, et al. Impact of protein supplementation after bariatric surgery: a randomized controlled double-blind pilot study. Nutrition. 2016;32(2):186–92.

    Article  CAS  PubMed  Google Scholar 

  20. Olbers T, Bjorkman S, Lindroos A, et al. Body composition, dietary intake, and energy expenditure after laparoscopic roux-en-Y gastric bypass and laparoscopic vertical banded gastroplasty: a randomized clinical trial. Ann Surg. 2006;244(5):715–22.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Brethauer SA, Heneghan HM, Eldar S, et al. Early effects of gastric bypass on endothelial function, inflammation, and cardiovascular risk in obese patients. Surg Endosc. 2011;25(8):2650–9.

    Article  PubMed  Google Scholar 

  22. Quercia I, Dutia R, Kotler DP, et al. Gastrointestinal changes after bariatric surgery. Diabetes Metab. 2014;40(2):87–94.

    Article  CAS  PubMed  Google Scholar 

  23. Soares FL, Sousa L, Corradi-Perini C, et al. Food quality in the late postoperative period of bariatric surgery: an evaluation using the bariatric food pyramid. Obes Surg. 2014;24(9):1481–6.

    Article  PubMed  Google Scholar 

  24. Moreira MDA, Espínola PRM, Azevedo CWD. Food intolerances and associated symptoms in patients undergoing Fobi-Capella technique without gastric ring. Arq Bras Cir Dig. 2015;28(1):36–9.

    Article  PubMed Central  Google Scholar 

  25. Di Vetta V, Kraytem A, Giusti V. Gastric bypass: management of complications and food tolerance. Rev Med Suisse. 2008;4(151):836–8. 840-2

    PubMed  Google Scholar 

  26. Nicoletti CF, Oliveira BAP, Barbin R, et al. Red meat intolerance in patients submitted to gastric bypass: a 4-year follow-up study. Surg Obes Relat Dis. 2015;11(4):842–6.

    Article  PubMed  Google Scholar 

  27. Poslusna K, Ruprich J, de Vries JH, et al. Misreporting of energy and micronutrient intake estimated by food records and 24 hour recalls, control and adjustment methods in practice. Br J Nutr. 2009;101(Suppl 2):S73–85.

    Article  CAS  PubMed  Google Scholar 

  28. Ma Y, Olendzki BC, Pagoto SL, et al. Number of 24-h diet recalls needed to estimate energy intake. Ann Epidemiol. 2009;19(8):553–9.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Chaston TB, Dixon JB, O'Brien PE. Changes in fat-free mass during significant weight loss: a systematic review. Int J Obes. 2007;31(5):743–50.

    CAS  Google Scholar 

  30. Gomes D, Oliveira D, Dutra E, et al. Resting energy expenditure and body composition of women with weight regain 24 months after bariatric surgery. Obes Surg. 2015; 1–5.

  31. Faria SL, Kelly E, Faria OP. Energy expenditure and weight regain in patients submitted to roux-en-Y gastric bypass. Obes Surg. 2009;19(7):856–9.

    Article  PubMed  Google Scholar 

  32. Coppini LZ, Waitzberg DL, Campos AC. Limitations and validation of bioelectrical impedance analysis in morbidly obese patients. Curr Opin Clin Nutr Metab Care. 2005;8(3):329–32.

    Article  PubMed  Google Scholar 

  33. Faria SL, Faria OP, Cardeal MD, et al. Validation study of multi-frequency bioelectrical impedance with dual-energy X-ray absorptiometry among obese patients. Obes Surg. 2014;24(9):1476–80.

    Article  PubMed  Google Scholar 

  34. Widen EM, Strain G, King WC, et al. Validity of bioelectrical impedance analysis for measuring changes in body water and percent fat after bariatric surgery. Obes Surg. 2014;24(6):847–54.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Ritz P, Becouarn G, Douay O, et al. Gastric bypass is not associated with protein malnutrition in morbidly obese patients. Obes Surg. 2009;19(7):840–4.

    Article  PubMed  Google Scholar 

  36. Shikora SA, Kim JJ, Tarnoff ME. Nutrition and gastrointestinal complications of bariatric surgery. Nutr Clin Pract. 2007;22(1):29–40.

    Article  PubMed  Google Scholar 

  37. Aills L, Blankenship J, Buffington C, et al. ASMBS allied health nutritional guidelines for the surgical weight loss patient. Surg Obes Relat Dis. 2008;4:S73–S108.

    Article  PubMed  Google Scholar 

  38. Charney P, Malone A. ADA pocket guide to nutrition assessment: American dietetic association. Chicago, Illinois: American Dietetic Association; 2009 .66p

    Google Scholar 

  39. Aron-Wisnewsky J, Verger EO, Bounaix C, et al. Nutritional and protein deficiencies in the short term following both gastric bypass and gastric banding. PLoS One. 2016;11(2):e0149588.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Veldhorst M, Smeets A, Soenen S, et al. Protein-induced satiety: effects and mechanisms of different proteins. Physiol Behav. 2008;94(2):300–7.

    Article  CAS  PubMed  Google Scholar 

  41. Bray GA, Smith SR, de Jonge L, et al. Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating: a randomized controlled trial. JAMA. 2012;307(1):47–55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Prof. Mauricio G. Pereira for his valuable contribution to the EMBASE data search and discussion on study designs.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Silvia Leite Campos Martins Faria.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

Does not apply.

Informed Consent

Does not apply.

Electronic supplementary material

ESM 1

(DOCX 18 kb)

ESM 2

(DOCX 150 kb)

ESM 3

(DOCX 23 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ito, M.K., Gonçalves, V.S.S., Faria, S.L.C.M. et al. Effect of Protein Intake on the Protein Status and Lean Mass of Post-Bariatric Surgery Patients: a Systematic Review. OBES SURG 27, 502–512 (2017). https://doi.org/10.1007/s11695-016-2453-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11695-016-2453-0

Keywords

Navigation