Obesity Surgery

, Volume 26, Issue 6, pp 1335–1342 | Cite as

Copper Deficiency after Gastric Bypass for Morbid Obesity: a Systematic Review

  • Parveen Kumar
  • Numan Hamza
  • Brijesh Madhok
  • Nimantha De Alwis
  • Manisha Sharma
  • Alexander Dimitri Miras
  • Kamal K. MahawarEmail author
Review Article


A large number of patients undergoing bariatric surgery are deficient in copper, and Roux-en-Y gastric bypass can further aggravate it. Delays in diagnosis and treatment of copper deficiency can leave patients with residual neurological disability. This has led to recommendation from the British Obesity and Metabolic Surgery Society that copper levels should be monitored annually after gastric bypass. This review concludes that copper deficiency in adequately supplemented patients is rare and can be adequately treated if a related haematological or neurological disorder is diagnosed. The cost of routine monitoring may therefore not be justified for adequately supplemented, asymptomatic patients who have undergone Roux-en-Y gastric bypass. The screening may however be necessary for high-risk patient groups to prevent severe complications and permanent disability.


Morbid obesity Bariatric surgery Gastric bypass Copper 



American Society for Metabolic and Bariatric Surgery


British Obesity and Metabolic Surgery Society




Preferred Reporting Items for Systematic Reviews and Meta-Analyses


Roux-en-Y gastric bypass


Authors’ Contributions

KM conceived the idea for the topic. PK, KM, NH independently collected information and analysed it. All authors participated in discussions on the topic and manuscript writing. All authors have seen the final version and approve of it.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

Not applicable


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Parveen Kumar
    • 1
  • Numan Hamza
    • 2
  • Brijesh Madhok
    • 2
  • Nimantha De Alwis
    • 2
  • Manisha Sharma
    • 3
  • Alexander Dimitri Miras
    • 4
  • Kamal K. Mahawar
    • 2
    Email author
  1. 1.Department of General SurgerySir Charles Gairdner HospitalNedlandsAustralia
  2. 2.Bariatric Unit, Department of General SurgerySunderland Royal HospitalSunderlandUK
  3. 3.Department of Chemical PathologyHomerton University Hospital NHS TrustLondonUK
  4. 4.Division of Diabetes, Endocrinology and MetabolismImperial College LondonLondonUK

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