Weight Regain Following Sleeve Gastrectomy—a Systematic Review
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Sleeve gastrectomy (SG) is a commonly performed bariatric procedure. Weight regain following SG is a significant issue. Yet the defining, reporting and understanding of this phenomenon remains largely neglected. Systematic review was performed to locate articles reporting the definition, rate and/or cause of weight regain in patients at least 2 years post-SG. A range of definitions employed to describe weight regain were identified in the literature. Rates of regain ranged from 5.7 % at 2 years to 75.6 % at 6 years. Proposed causes of weight regain included initial sleeve size, sleeve dilation, increased ghrelin levels, inadequate follow-up support and maladaptive lifestyle behaviours. Bariatric literature would benefit from standardising definitions used to report weight regain and its rate in clinical series. Larger prospective studies are required to further understand mechanisms of weight regain following SG.
KeywordsBariatric surgery Sleeve gastrectomy Weight regain
The research was conducted during tenure of a Clinical Research Training Fellowship (author ML) from the Health Research Council of New Zealand.
Compliance with Ethical Standards
This article does not contain any studies with human participants or animals performed by any of the authors.
Conflict of Interest
This study was conducted whilst author ML held a Health Research Council of New Zealand Clinical Research Training Fellowship (15/008). The senior author has received fees from Covidien for a speaker honorarium. The remaining authors have nothing to declare.
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- 20.Casella G, Soricelli E, Giannotti D, Collalti M, Maselli R, Genco A, et al. Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series. Surg Obes Relat Dis. 2016. doi: 10.1016/j.soard.2015.09.028
- 32.Lombardo M, Bellia A, Mattiuzzo F, et al. Frequent follow-up visits reduce weight regain in long-term management after bariatric surgery. Bariatr Surg Pract Patient Care. 2015;10(3):119–25.Google Scholar
- 47.Karamanakos SN, Vagenas K, Kalfarentzos F, et al. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg. 2008;247(3):401–7.CrossRefPubMedGoogle Scholar