Obesity Surgery

, Volume 19, Issue 2, pp 247–249 | Cite as

Carcinoid Tumors and Morbid Obesity

  • Cláudio Corá Mottin
  • Ricardo Pedrini Cruz
  • Gustavo Gomes Thomé
  • Alexandre Vontobel Padoin
Case Reports

Abstract

Carcinoid is a rare gastrointestinal tumor, with an incidence varying from 1 to 2.5 per 100,000 in the general population. In this article, we report an elevated incidence of carcinoid tumor in an obese population, showing the importance of performing an endoscopic procedure before bariatric surgery.

Keywords

Carcinoid tumor Gastric carcinoid Duodenal carcinoid Morbid obesity Bariatric surgery Neuroendocrine tumor 

References

  1. 1.
    Langhans T. Ueber einen drusenpolyp im ileum. Virchow Arch Pathol Anat Physiol Klin Med. 1867;38:559–60.CrossRefGoogle Scholar
  2. 2.
    Obendorfer S. Karzinoide tumoren des Dunndarms. Frankfurt Zeitschr Pathol. 1907;1:426–32.Google Scholar
  3. 3.
    Mulkeen A, Cha C. Gastric carcinoid. Curr Opin Oncol. 2005;17:1–6.CrossRefPubMedGoogle Scholar
  4. 4.
    Maggard MA, O’Connell JB, Ko CY. Updated population-based review of carcinoid tumors. Ann Surg. 2004;240:117–22.CrossRefPubMedGoogle Scholar
  5. 5.
    Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer. 2003;97:934–59.CrossRefPubMedGoogle Scholar
  6. 6.
    Keshishian A, Hamilton J, Hwang L, Petrosyan M. Carcinoid tumor and bariatric surgery. Obes Surg. 2002;12:874–5.CrossRefPubMedGoogle Scholar
  7. 7.
    Onaitis MW, Kirshbom PM, Hayward TZ, et al. Gastrointestinal carcinoids: characterization by site of origin and hormone production. Ann Surg. 2000;232:549–56.CrossRefPubMedGoogle Scholar
  8. 8.
    Kulke MH, Mayer RJ. Carcinoid tumors. N Engl J Med. 1999;340:858–68.CrossRefPubMedGoogle Scholar
  9. 9.
    Modlin IM, Sandor A. An analysis of 8305 cases of carcinoid tumors. Cancer. 1997;79:813–29.CrossRefPubMedGoogle Scholar
  10. 10.
    Godwin JD II. Carcinoid tumors. An analysis of 2,837 cases. Cancer. 1975;36:560–9.CrossRefPubMedGoogle Scholar
  11. 11.
    Borch K, Ahren B, Ahlman H, Falkmer S, Granerus G, Grimelius L. Gastric carcinoids: biologic behavior and prognosis after differentiated treatment in relation to type. Ann Surg. 2005;242:64–73.CrossRefPubMedGoogle Scholar
  12. 12.
    Modlin IM, Lye KD, Kidd M. A 50-year analysis of 562 gastric carcinoids: small tumor or larger problem? Am J Gastroenterol. 2004;99:23–32.CrossRefPubMedGoogle Scholar
  13. 13.
    Christopoulos C, Papavassiliou E. Gastric neuroendocrine tumors: biology and management. Ann Gastroenterol. 2005;18:127–40.Google Scholar
  14. 14.
    Moghaddam AA, Woodward M, Huxley R. Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events. Cancer Epidemiol Biomarkers Prev. 2007;16:2533–47.CrossRefPubMedGoogle Scholar
  15. 15.
    Boru C, Silecchia G, Pecchia A, et al. Prevalence of cancer in Italian obese patients referred for bariatric surgery. Obes Surg. 2005;15:1171–6.CrossRefPubMedGoogle Scholar
  16. 16.
    Granberg D, Wilander E, Stridsberg M, Granerus G, Skogseid B, Oberg K. Clinical symptoms, hormone profiles, treatment, and prognosis in patients with gastric carcinoids. Gut. 1998;43:223–8.PubMedCrossRefGoogle Scholar
  17. 17.
    Gilligan CJ, Lawton GP, Tang LH, West AB, Modlin IM. Gastric carcinoid tumors: the biology and therapy of an enigmatic and controversial lesion. Am J Gastroenterol. 1995;90:338–52.PubMedGoogle Scholar
  18. 18.
    Jordan PH, Jr., Barroso A, Sweeney J. Gastric carcinoids in patients with hypergastrinemia. J Am Coll Surg. 2004;199:552–5.CrossRefPubMedGoogle Scholar
  19. 19.
    Schindl M, Kaserer K, Niederle B. Treatment of gastric neuroendocrine tumors: the necessity of a type-adapted treatment. Arch Surg. 2001;136:49–54.CrossRefPubMedGoogle Scholar
  20. 20.
    Wangberg B, Grimelius L, Granerus G, Conradi N, Jansson S, Ahlman H. The role of gastric resection in the management of multicentric argyrophil gastric carcinoids. Surgery. 1990;108:851–7.PubMedGoogle Scholar
  21. 21.
    Korenkov M, Sauerland S, Shah S, Junginger T. Is routine preoperative upper endoscopy in gastric banding patients really necessary? Obes Surg. 2006;16:45–7.CrossRefPubMedGoogle Scholar
  22. 22.
    Azagury D, Dumonceau JM, Morel P, Chassot G, Huber O. Preoperative work-up in asymptomatic patients undergoing Roux-en-Y gastric bypass: is endoscopy mandatory? Obes Surg. 2006;16:1304–11.CrossRefPubMedGoogle Scholar
  23. 23.
    Zeni TM, Frantzides CT, Mahr C, et al. Value of preoperative upper endoscopy in patients undergoing laparoscopic gastric bypass. Obes Surg. 2006;16:142–6.CrossRefPubMedGoogle Scholar
  24. 24.
    Sharaf RN, Weinshel EH, Bini EJ, Rosenberg J, Sherman A, Ren CJ. Endoscopy plays an important preoperative role in bariatric surgery. Obes Surg. 2004;14:1367–72.CrossRefPubMedGoogle Scholar
  25. 25.
    Schirmer B, Erenoglu C, Miller A. Flexible endoscopy in the management of patients undergoing Roux-en-Y gastric bypass. Obes Surg. 2002;12:634–8.CrossRefPubMedGoogle Scholar
  26. 26.
    Harper JL, Beech D, Tichansky DS, Madan AK. Cancer in the bypassed stomach presenting early after gastric bypass. Obes Surg. 2007;17:1268–71.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science + Business Media, LLC 2008

Authors and Affiliations

  • Cláudio Corá Mottin
    • 1
  • Ricardo Pedrini Cruz
    • 1
  • Gustavo Gomes Thomé
    • 1
  • Alexandre Vontobel Padoin
    • 1
  1. 1.Centro da Obesidade MórbidaHospital São Lucas da Pontifícia Universidade Católica do Rio Grande do SulPorto AlegreBrazil

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