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Sleeve Gastrectomy as Treatment for Severe Obesity after Orthotopic Liver Transplantation

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Obesity is highly prevalent in both liver transplant candidates and recipients, and can have a significant impact on perioperative morbidity and mortality and the overall cost of transplantation. Herein, we describe an obese patient who was managed sequentially with an intragastric balloon in the pre-transplant setting and a gastric sleeve following transplantation, with good long-term results. Sleeve gastrectomy is a non-malabsorptive bariatric procedure with potential benefit for liver transplant patients due to its lack of influence on the absorption of immunosuppressive agents.

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  1. Deitel M. Some consequences of the global obesity epidemic. Obes Surg 2005; 15: 1–2.

    Article  PubMed  Google Scholar 

  2. Deitel M. The obesity epidemic. Obes Surg 2006; 16: 377–8.

    Article  PubMed  Google Scholar 

  3. Munoz SJ, Elgenaidi H. Cardiovascular risk factors after liver transplantation. Liver Transpl 2005; 11: S52–S56.

    Google Scholar 

  4. Nair S, Verma S, Thuluvath PJ. Obesity and its effect on survival in patients undergoing orthotopic liver transplantation in the United States. Hepatology 2002; 35: 105–9.

    Article  PubMed  Google Scholar 

  5. Nair S, Cohen DB, Cohen MP et al. Postoperative morbidity, mortality, costs, and long-term survival in severely obese patients undergoing orthotopic liver transplantation. Am J Gastroenterol 2001; 96: 842–5.

    Article  PubMed  CAS  Google Scholar 

  6. Correia TDMI, Rego LO, Lima AS. Post-liver transplant obesity and diabetes. Curr Opin Clin Nutr Metab Care 2003; 6: 457–60.

    Article  Google Scholar 

  7. Angulo P. Nonalcoholic fatty liver disease and liver transplantation. Liver Transpl 2006; 12: 523–34.

    Article  PubMed  Google Scholar 

  8. Adams LA, Angulo P, Lindor KD. Nonalcoholic fatty liver disease. CMAJ 2005; 172: 899–905.

    PubMed  Google Scholar 

  9. Neuschwander-Tetri BA. Fatty liver and the metabolic syndrome. Curr Opin Gastroenterol 2007; 23: 193–8.

    Article  PubMed  CAS  Google Scholar 

  10. Helling TS, Gurram K. Nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and bariatric surgery: a review. Surg Obes Relat Dis 2006; 2: 213–20.

    Article  PubMed  Google Scholar 

  11. Adams LA, Angulo P. Recent concepts in non-alcoholic fatty liver disease. Diabet Med 2005; 22: 1129–33.

    Article  PubMed  CAS  Google Scholar 

  12. Costamagna G, Shah SK, Tringali A. Current management of postoperative complications and benign biliary strictures. Gastrointest Endosc Clin North Am 2003; 13: 635–48.

    Article  Google Scholar 

  13. Karlsson J, Taft C, Ryden A et al. Ten-year trends in health-related quality of life after surgical and conventional treatment for severe obesity: the SOS intervention study. Int J Obes 2007; 31: 1248–61.

    Article  CAS  Google Scholar 

  14. Tichansky DS, Madan AK. Laparoscopic Roux-en-Y gastric bypass is safe and feasible after orthotopic liver transplantation. Obes Surg 2005; 15: 1481–6.

    Article  PubMed  Google Scholar 

  15. Duchini A, Brunson ME. Roux-en-Y gastric bypass for recurrent nonalcoholic steatohepatitis in liver transplant recipients with morbid obesity. Transplantation 2001; 72: 156–9.

    Article  PubMed  CAS  Google Scholar 

  16. Kim WR, Poterucha JJ, Porayko MK et al. Recurrence of nonalcoholic steatohepatitis following liver transplantation. Transplantation 1996; 62: 1802–5.

    Article  PubMed  CAS  Google Scholar 

  17. Charlton M, Kasparova P, Weston S et al. Frequency of nonalcoholic steatohepatitis as a cause of advanced liver disease. Liver Transpl 2001; 7: 608–14.

    Article  PubMed  CAS  Google Scholar 

  18. Mognol P, Chosidow D, Marmuse JP. Laparoscopic sleeve gastrectomy (LSG): review of a new bariatric procedure and initial results. Surg Technol Int 2006; 15: 47–52.

    PubMed  Google Scholar 

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Correspondence to Jorge Martínez MD.

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Butte, J.M., Devaud, N., Jarufe, N.P. et al. Sleeve Gastrectomy as Treatment for Severe Obesity after Orthotopic Liver Transplantation. OBES SURG 17, 1517–1519 (2007).

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