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Fucoxanthin as antioxidant, anti-hyaluronidase and cytotoxic agent: potential of brown seaweeds decoction for tea supplement

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Abstract

The decoctions of Dictyota dichotoma, Padina gymnospora, Sargassum wightii, Turbinaria conoides, tea leaf (Camellia sinensis), and commercial tea were prepared separately. The antioxidant, anti-hyaluronidase (anti-wrinkling) and cytotoxic activities of decoctions were assessed. The decoctions were added with milk tea and assessed their physio-palatable property. The results showed that among the four seaweed decoctions (BSDs), Dictyota dichotoma exhibits a remarkable antioxidant, anti-hyaluronidase and cytotoxic properties. The decoctions of tea leaf, Dictyota dichotoma, Padina gymnospora, Turbinaria conoides and Sargassum wightii had the cytotoxic property with IC50 of 64.68, 73.24, 161.35, 203.52, 218.73 µg/ml, respectively against HeLa cell lines. The FTIR of the BSD confirmed the presence of fucoxanthin as the principal compound. After adding milk, the mixture of decoctions prepared by tea and brown seaweeds the pH was increased from 4.97 (commercial tea) to 6.93 (Dictyota dichotoma) that would protect teeth from correction caused by acidic tea decoction besides other health benefits. Hence, it can be used as a healthy and nutritious tea drink to protect the skin from solar radiation as values addition to tea.

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Authors and Affiliations

  1. Phycoscience Laboratory, Department of Plant Science, School of Biological Sciences, Central University of Kerala, Periye, Kasaragod, Kerala, 671 320, India

    K. Arunkumar, Madhuri Nalluri, K. Anjana & G. Mohan

  2. Research and Development Wing, Sree Balaji Medical College and Hospital (SBMCH), Bharath Institute of Higher Education and Research (BIHER), Chennai, 600 044, India

    Rathinam Raja

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Arunkumar, K., Nalluri, M., Anjana, K. et al. Fucoxanthin as antioxidant, anti-hyaluronidase and cytotoxic agent: potential of brown seaweeds decoction for tea supplement. Food Measure 17, 3980–3989 (2023). https://doi.org/10.1007/s11694-023-01911-x

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