Skip to main content
SpringerLink
Log in

Encapsulation of quantum dots and carbon nanotubes with polypyrrole in a syringe needle for automated molecularly imprinted solid phase pre-concentration of ochratoxin A in red wine analysis

  • Original Paper
  • Published:
Sensing and Instrumentation for Food Quality and Safety Aims and scope Submit manuscript

Abstract

Nanometer-sized semiconductor quantum dots (QDs with CdSe core and ZnS shell) and carbon nanotubes (CNTs with multi-walls) were encapsulated inside a stainless steel syringe needle by electrodeposition of polypyrrole (PPy). By cross-linking the PPy with ethylene glycol dimethacrylate (EGDMA) in the presence of ochratoxin A (OTA) as a template, molecularly imprinted polypyrrole (MIPPy) was formed on the nano-hybrid structure at an increased specific surface area. The MIPPy/CNTs/QDs-modified needle was readily adapted in an autosampler for micro-solid phase preconcentration (μSPP) of OTA from a red wine sample. After pulsed elution (PE) with 2% triethylamine (TEA), the OTA was determined by high performance liquid chromatography (HPLC) with fluorescence detection (FD). In comparison with MIPPy/CNTs, this new nano-hybrid structure of MIPPy/CNTs/QDs significantly improved the % recovery of OTA. The method, MIPPy/CNTs/QDs-μSPP-HPLC-FD, demonstrated that the MIPPy was truly a molecularly imprinted polymer (MIP) with specific recognition for OTA. All red wine matrix components could be differentially washed out, prior to accurate determination of the strongly bound OTA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10

Similar content being viewed by others

References

  1. www.nature.com/nprot/journal/v1/n3/full/nprot.2006.184.html

  2. www.physorg.com/news536.html

  3. www.sciencemag.org/cgi/content/full/300/5616/80

  4. www.sciencemag.org/cgi/content/full/307/5709/538

  5. J.M. Perkel, Scientist 16, 32–34 (2002)

    Google Scholar 

  6. scienceweek.com/2003/sw030321.htm

  7. materials.globalspec.com/.../Electrical_Optical_Specialty_Materials /Nanomaterials_Nanotechnology_Products - 60k –

  8. www.nature.com/nmeth/journal/v1/n1/full/nmeth032.html

  9. www.cdc.gov/niosh/topics/nanotech/safenano/healthconcerns.html

  10. E.H. Sargent, Adv. Mater. 17, 515–522 (2005)

    Article  CAS  Google Scholar 

  11. www.mrs.org/s_mrs/bin.asp?CID=2629&DID=61013&DOC=FILE.PDF

  12. X. Gao, W.C.W. Chan, S. Nie, J. Biomed. Opt. 7, 532–537 (2002)

    Article  CAS  Google Scholar 

  13. http://www.esm.psu.edu/news/item/274

  14. P.G. Su, Y.L. Sun, C.C. Lin, Sensor. Actuat. B Chem. 115, 338–343 (2006)

    Article  Google Scholar 

  15. S. Ravindran, K.N. Bozhilov, C.S. Ozkan, Carbon 42, 1537–1542 (2004)

    Article  CAS  Google Scholar 

  16. J.C.C. Yu, S. Krushkova, E.P.C. Lai, E. Dabek-Zlotorzynska, Anal. Bioanal. Chem. 382, 1534–1540 (2005)

    Article  CAS  Google Scholar 

  17. J.C.C. Yu, E.P.C. Lai, React. Funct. Polym. 66, 702–711 (2006)

    Article  CAS  Google Scholar 

  18. Y. Wei, L. Qiu, J.C.C. Yu, E.P.C. Lai, Molecularly imprinted solid phase extraction in a syringe needle packed with polypyrrole-encapsulated carbon nanotubes for determination of ochratoxin A in red wine, Food Sci. Technol. Int., in press

  19. A. Wang, F. Fang, J. Pawliszyn, J. Chromatogr. A 1072, 127 (2005)

    Article  CAS  Google Scholar 

  20. C. Brera, J.M. Soriano, F. Debegnach, M. Miraglia, Microchem. J. 79, 109–113 (2005)

    Article  CAS  Google Scholar 

  21. E. González-Peñas, C. Leache, M. Viscarret et al., J. Chromatogr. A 1025, 163–168 (2004)

    Article  Google Scholar 

  22. Jorn C.C. Yu, Edward P.C. Lai, Determination of ochratoxin A in red wines by multiple pulsed elutions from molecularly imprinted polypyrrole, Food Chem., accepted (November 15, 2006)

  23. J.J. Gooding, C. Wasiowycha, D. Barnett, D.B. Hibbert, J.N. Barisci, G.G. Wallace, Biosens. Bioelectron. 20, 260–268 (2004)

    Article  CAS  Google Scholar 

  24. J.C.C. Yu, E.P.C. Lai, Anal. Bioanal. Chem. 381, 948–952 (2005)

    Article  CAS  Google Scholar 

  25. S. Sadki et al., Chem. Soc. Rev. 29, 283–293 (2000)

    Article  Google Scholar 

  26. X. Zhang, R. Bai, Langmuir 19, 1073–1079 (2003)

    Google Scholar 

  27. Kwok-Siong. Teh, Liwei Lin, J. Micromech. Microeng. 15, 2019–2027 (2005)

    Article  CAS  Google Scholar 

  28. icon.rice.edu/resources.cfm?doc_id=4394

  29. J.J. Gooding, C. Wasiowych, D. Barnett, D.B. Hibbert, J.N. Barisci, G.G. Wallace, Biosens. Bioelectron. 20, 260–268 (2004)

    Article  CAS  Google Scholar 

  30. P. Varelis, S.L. Leong, A. Hocking, G. Giannikopoulos, Food Addit. Contam. 23, 1308–1315 (2006)

    Article  CAS  Google Scholar 

  31. J.O. Mahoney, K. Nolan, M.R. Smyth, B. Mizaikoff, Anal. Chim. Acta 534, 31–39 (2005)

    Article  Google Scholar 

  32. W.M. Mullett, E.P.C. Lai, Microchem. J. 61, 143–155 (1999)

    Article  CAS  Google Scholar 

  33. S.Y. Feng, E.P.C Lai, E. Dabek-Zlotorzynska, S. Sadeghi, J. Chromatogr. A. 1027, 155–160 (2004)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

Financial support of the Natural Sciences and Engineering Research Council (NSERC) Canada is gratefully acknowledged.

Author information

Authors and Affiliations

  1. Ottawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University, Ottawa, ON, Canada, K1S 5B6

    Yun Wei, Longhui Qiu, Craig Owen & Edward P. C. Lai

Authors
  1. Yun Wei
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Longhui Qiu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Craig Owen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Edward P. C. Lai
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Edward P. C. Lai.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wei, Y., Qiu, L., Owen, C. et al. Encapsulation of quantum dots and carbon nanotubes with polypyrrole in a syringe needle for automated molecularly imprinted solid phase pre-concentration of ochratoxin A in red wine analysis. Sens. & Instrumen. Food Qual. 1, 133–141 (2007). https://doi.org/10.1007/s11694-007-9014-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11694-007-9014-0

Keywords

Search

Navigation