Active Transmission of Trypanosoma cruzi in Schoolchildren from the Amazon Region in Napo Province, Ecuador



Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a vector-borne disease with a major disease burden in the Americas, with over 6 million cases. There are about 200,000 cases in Ecuador, but the epidemiology of the disease is poorly understood, particularly in the Amazon region, making surveillance and control challenging.


We determined here the seroprevalence of T. cruzi antibodies in a cohort of 516 schoolchildren aged 5–15 years from Chontapunta parish, in the Napo province, Ecuador, using ELISA and indirect hemaglutination tests.


We detected a seroprevalence of 0.77% (95% confidence interval 0.31–1.97%), with some significant variation among the three studied communities.


These data provide evidence of the ongoing transmission of T. cruzi in this area, and support the need to strengthen epidemiological surveillance and patient care.

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This work was funded in part by grant # 632083 from Tulane University School of Public Health and Tropical Medicine to ED.

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Correspondence to Eric Dumonteil.

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The authors declare that they have no conflict of interest.

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The study was carried out as part of the routine epidemiologic surveillance activities of the National Reference Center from the National Institute of Public Health (INSPI).

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Carrera Vargas, C., Solorzano, L., Guale, D. et al. Active Transmission of Trypanosoma cruzi in Schoolchildren from the Amazon Region in Napo Province, Ecuador. Acta Parasit. (2021).

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  • Chagas disease
  • American trypanosomiasis
  • Seroprevalence
  • Diagnostic
  • Pediatric