Aberrant brain gray matter in murderers
Homicide is a significant societal problem with economic costs in the billions of dollars annually and incalculable emotional impact on victims and society. Despite this high burden, we know very little about the neuroscience of individuals who commit homicide. Here we examine brain gray matter differences in incarcerated adult males who have committed homicide (n = 203) compared to other non-homicide offenders (n = 605; total n = 808). Homicide offenders’ show reduced gray matter in brain areas critical for behavioral control and social cognition compared with subsets of other violent and non-violent offenders. This demonstrates, for the first time, that unique brain abnormalities may distinguish offenders who kill from other serious violent offenders and non-violent antisocial individuals.
KeywordsBrain imaging Homicide Voxel-based morphometry Violence Antisocial behavior
The authors would like to thank the Wisconsin Department of Corrections and the New Mexico Department of Corrections for their cooperative efforts with the Mind Research Network.
This research was supported in part by grants from the National Institute of Mental Health: R01DA026505, R01DA026964, R01DA020870, R01MH070539, and R01MH087525 (PI: Kent Kiehl), R01MH087525 (PI: Jean Decety), R01MH090169 (PI: David Kosson) and the Macarthur Foundation Law and Neuroscience Project.
Compliance with ethical standards
Conflict of interest
The authors report no competing interests.
This research was approved by multiple IRBs, including the Ethical and Independent Review Services (E&I), the University of Wisconsin-Madison, divisions of the Corrections Department of Wisconsin and The New Mexico Corrections Department as well as the Office of Human Research Protections (OHRP).
All individuals volunteered to participate after providing written informed consent. Participation did not affect institutional status (e.g., security level, privileges, and parole or release date) and participants were paid for their time at a rate commensurate with pay for work assignments at their facility.
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