Abstract
Objective
To discuss the epidemic strength of cardia and distant stomach cancers in the high risk region of esophageal cancer along the south Taihang mountain such as in Shexian, Linxian, and Cixian Counties, and to clarify the tasks for the control of upper gastrointestinal tract cancer as a whole in the region.
Methods
Comparisons of incidence and mortality rates of esophageal, cardia and stomach cancers were made between Cixian, Linxian and Shexian Counties with reference to detection rates of cancer in situ and precancerous lesions of the three upper gastrointestinal cancers by endoscopic screening. The screening was performed from 1999 through 2004 in the three adjacent counties including a total of 6233 local residents aged 40 to 69 years old.
Results
The incidence rates for cardia cancer for the male and female from 2000 through 2004 were 69.9 and 41.5, and the mortality rates were 54.3 and 33.2 respectively in Shexian County. Esophageal, cardia, and stomach cancers constitute about 70∼80 percent of all malignant disease by incidence or mortality rates. Endoscopic survey with iodine staining can effectively detect squamous cell precancerous lesions in the esophagus, but the method is inadequate for the detection of adeno precancerous lesions of the cardia and stomach.
Conclusion
The south Taihang mountain region is a high risk area not only for esophagus cancer, but also for cardia and stomach cancers. To control upper gastrointestinal tract cancers as a whole in the region, special attention should be paid to the control of cardia and stomach cancers. Presently, to find effective screening methods for detecting cardia and stomach precancerous lesions is especially important.
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Foundation item: This work was supported by the grants from The Natural Scientific Foundation of Hebei Province (No. C 2005000797; Hebei Significant Topic of Tackle Key Programs (No. 03276198D); Hebei Technology Program Item (No. 032761100D-1)
Biography: ZHANG Li-wei(1958–), female, professor, Department of Endoscopy, Fourth Hospital of Hebei Medical University, majors in endoscopy.
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Zhang, Lw., Wen, Dg., Li, Ys. et al. Epidemic strength of cardia and distant stomach cancer in the high risk region of esophageal cancer and their implication to edoscopic screening. Chin. J. Cancer Res. 18, 111–115 (2006). https://doi.org/10.1007/s11670-006-0111-0
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DOI: https://doi.org/10.1007/s11670-006-0111-0
Key words
- High-risk region for esophageal cancer
- Cardia cancer
- Stomach cancer
- Precancerous disease
- Endoscopic screening