Abstract
Ti-15Mo (β-Ti) alloy was subjected to chemical followed by thermal treatment for the enhancement of in vitro bioactivity and corrosion resistance. The surface-modified specimens were characterized using scanning electron microscopy (SEM) and energy dispersive x-ray analysis (EDAX). The results indicated the formation of nanoporous layer and flake-like structure developed during chemical and subsequent thermal treatments. The in vitro bioactivity of the surface-treated β-Ti alloy was evaluated by immersing in simulated body fluid (SBF) solution. The formation of apatite particles was confirmed using Fourier transform-infrared spectroscopy, SEM, and EDAX analyses. Moreover, the electrochemical behavior of surface-modified specimens in SBF solution was evaluated using potentiodynamic polarization and electrochemical impedance spectroscopy. The results revealed that the surface-modified specimens exhibited higher potential value and lower current density when compared to untreated specimen. The EIS studies showed the formation of new layer, indicating the growth of apatite-like particles.
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E. Leitao, R.A. Silva, and M.A. Barbosa, Electrochemical Impedance Spectroscopy of Nitrogen and Carbon Sputter Coated 316 L Stainless Steel, Corros. Sci., 1997, 39, p 333–338
J. Pan, D. Thierry, and C. Leygraf, Electrochemical Impedance Spectroscopy Study of the Passive Oxide Film on Titanium for Implant Application, Electrochim. Acta, 1996, 41, p 1143–1153
T. Kokubo, F. Miyaji, and H.M. Kim, Spontaneous Formation of Bonelike Apatite Layer on Chemically Treated Titanium Metals, J. Am. Ceram. Soc., 1996, 4, p 1127–1129
H.M. Kim, Y. Sasaki, J. Suzuki, S. Fujibayashi, T. Kokubo, T. Matsushita, and T. Nakamura, Mechanical Properties of Bioactive Titanium Metal Prepared by Chemical Treatment, Key Eng. Mater., 2001, 192–195, p 227–230
S. Tamilselvi, V. Raman, and N. Rajendran, Corrosion Behaviour of Ti–6Al–7Nb and Ti–6Al–4V ELI, Alloys in the Simulated Body Fluid Solution by Electrochemical Impedance Spectroscopy, Electrochim. Acta, 2006, 52, p 839–846
V. Raman, S. Tamilselvi, and N. Rajendran, Electrochemical Impedance Spectroscopic Characterization of Titanium During Alkali Treatment and Apatite Growth in Simulated Body Fluid, Electrochim. Acta, 2007, 52, p 7418–7424
S. Tamilselvi, V. Raman, and N. Rajendran, Evaluation of Corrosion Behavior of Surface Modified Ti-6Al-4V ELI, Alloy in Hanks Solution, J. Appl. Electrochem., 2010, 40(2), p 285–293
E. Czarnowska, T. Wierzchon, and M. Niedbala, Properties of the Surface Layers on Titanium Alloy and Their Biocompatibility in In-Vitro Tests, J. Mater. Process. Technol., 1999, 92–93, p 190–194
D. Kuroda, M. Niinomi, M. Masahiko, Y. Kato, and T. Yashiro, Design and Mechanical Properties of New Type Titanium Alloys for Implants Materials, J. Biomed. Mater. Res., 1995, 29, p 943–950
N.T.C. Oliveria, G. Aleixo, R. Caram, and A.C. Guastaldi, Development of Ti–Mo Alloys for Biomedical Applications: Microstructure and Electrochemical Characterization, J. Mater. Sci. Eng. A, 2007, 452, p 727–731
N.T.C. Oliveria and A.C. Guastaldi, Electrochemical Behavior of Ti–Mo Alloys Applied as Biomaterial, Corros. Sci., 2008, 50(4), p 938–945
M. Karthega, V. Raman, and N. Rajendran, Influence of Potential on the Electrochemical Behaviour of β Titanium Alloys in Hank’s Solution, Acta Biomater., 2007, 3, p 1019–1023
T. Kokubo and H. Takadama, How Useful is SBF in Predicting In Vivo Bone Bioactivity, Biomaterials, 2005, 27, p 2907–2915
H.M. Kim, H. Takadama, T. Kokubo, S. Nishiguchi, and T. Nakamura, Formation of a Bioactive Graded Surface Structure on Ti–15Mo–5Zr–3Al Alloy by Chemical Treatment, Biomaterials, 2000, 21, p 353–358
F. Liang, L. Zhou, and K. Wang, Apatite Formation on Porous Titanium by Alkali And Heat-Treatment, Surf. Coat. Technol., 2003, 165, p 133–139
F. Liang, L. Zhou, and K. Wang, Enhancement of the Bioactivity of Alkali-Heat Treated Titanium by Pre-Calcification, J. Mater. Sci. Lett., 2003, 22, p 1665–1669
F.H. Lin, Y.S. Hsu, S.H. Lin, and T.M. Chen, The Growth of Hydroxyapatite on Alkaline Treated Ti–6Al–4V Soaking in Higher Temperature with Concentrated Ca2+/HPO42− simulated body fluid, Mater. Chem. Phys., 2004, 87, p 24–30
H.M. Kim, F. Miyaji, T. Kokubo, and T. Nakamura, Preparation of Bioactive Ti and its Alloys Via Simple Chemical Surface Treatment, J. Biomed. Mater. Res., 1996, 32, p 409–417
C. Dianying, H.J. Eric, G. Maurice, and W. Mei, Apatite Formation on Alkaline-Treated Dense TiO2 Coatings Deposited Using the Solution Precursor Plasma Spray Process, Acta Biomater., 2008, 4, p 553–559
M.M. Khaled, Potential Dependent Selective Dissolution of Ti–6Al–4V and Laser Treated Ti–6Al–4V in Acid/Chloride, J. Appl. Electrochem., 2003, 33, p 817–822
A.K. Shukla, R. Balasubramaniam, and S. Bhargava, Properties of Passive Film Formed on CP-Titanium, Ti–6Al–4V and Ti–13.4Al–29Nb Alloys in Simulated Human Body Conditions, Intermetallics, 2005, 13, p 631–637
S. Tamilselvi, V. Raman, and N. Rajendran, Surface Modification of Titanium by Chemical and Thermal Methods—Electrochemical Impedance Spectroscopic Studies, Corrosion Engineering Science and Technology, 2010. doi:10.1179/147842209X12590591256936
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The authors acknowledge the Indian Council for Medical Research (ICMR), New Delhi for their financial support.
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Sasikumar, Y., Karthega, M. & Rajendran, N. In Vitro Bioactivity of Surface-Modified β-Ti Alloy for Biomedical Applications. J. of Materi Eng and Perform 20, 1271–1277 (2011). https://doi.org/10.1007/s11665-010-9772-4
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DOI: https://doi.org/10.1007/s11665-010-9772-4