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Evidence for Anticancer Effects of Chinese Medicine Monomers on Colorectal Cancer

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Abstract

Colorectal cancer is one of the most commonly occurring cancers worldwide. Although clinical reports have indicated the anticancer effects of Chinese herbal medicine, the multiple underlying molecular and biochemical mechanisms of action remain to be fully characterized. Chinese medicine (CM) monomers, which are the active components of CM, serve as the material basis of the functional mechanisms of CM. The aim of this review is to summarize the current experimental evidence from in vitro, in vivo, and clinical studies for the effects of CM monomers in colorectal cancer prevention and treatment, providing some useful references for future research.

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Authors and Affiliations

  1. The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, 210023, China

    Tian-hao Guo, Yuan-yuan Li, Sheng-wei Hong, Qian-yu Cao, Heng Chen, Yuan Xu & Gang Shao

  2. Department of Clinical Pharmacology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China

    Guo-liang Dai

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Guo TH and Dai GL conceived the structure of article. Guo TH, Li YY, Hong SW, Cao QY, Chen H, and Xu Y searched literature. Guo TH and Hong SW wrote the paper. Guo TH, Li YY and Shao G reviewed and edited the manuscript. All authors read and approved the manuscript.

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Supported by the National Natural Science Foundation of China (No. 81973737)

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Guo, Th., Li, Yy., Hong, Sw. et al. Evidence for Anticancer Effects of Chinese Medicine Monomers on Colorectal Cancer. Chin. J. Integr. Med. 28, 939–952 (2022). https://doi.org/10.1007/s11655-022-3466-2

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