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Ethnopharmacology, Phytochemistry, Pharmacology, Toxicology and Clinical Applications of Radix Astragali

Chinese Journal of Integrative Medicine volume 27, pages 229–240 (2021)Cite this article

Abstract

Radix Astragali (RA), a traditional Chinese medicine from the dried root of Astragalus species, is widely distributed throughout the temperate regions of the world. The major bioactive constituents of RA are triterpene glycosides, flavonoids, saponins, and alkaloids, and these compounds mostly exert pharmacological activities on the cardiovascular, immune, respiratory, and hepatic systems. This review summarizes the recent studies on RA and provides a comprehensive summary regarding the status of resources, ethnopharmacology, phytochemistry, pharmacology, toxicology, clinical application, and patent release of RA. We hope this review can provide a guidance for further development of therapeutic agents from RA.

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Authors and Affiliations

  1. Department of Pharmacy, Baotou Medical College, Baotou, Inner Mongolia Autonomous Region, 014040, China

    Chun-hong Zhang, Na-mu-han Chen, Jian-ping Xu, Min Yang, Xue Gong, Zi-yan Li, Kai Ren, Qi-heng Han, Ming-yue Ji, Cong-cong Wang & Min-hui Li

  2. Department of Pharmacy, Inner Mongolia Medical University, Hohhot, 010020, China

    Xiao Yang, Jing-ran Wei, Lei Zhang & Xue Li

  3. Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot, 010020, China

    Ya-qiong Bi & Min-hui Li

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  1. Chun-hong Zhang
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  15. Cong-cong Wang
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  16. Min-hui Li
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Contributions

Zhang CH, Xu JP, Yang M, Li MH conceived the structure of article. Zhang CH, Yang X, Wei JR, Chen NMH, Xu JP, Bi YQ, Yang M, Gong X, Li ZY, Ren K, Han QH, Zhang L, Li X, Ji MY and Wang CC searched the literature. Zhang CH, Yang X and Xu JP wrote the paper. Zhang CH, Yang X, Chen NMH, Xu JP, Bi YQ, Yang M, Gong X, Ren K and Han QH reviewed and edited the manuscript. All authors read and approved the manuscript.

Corresponding author

Correspondence to Min-hui Li.

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There are no conflicts of interest.

Additional information

Supported by the Science and Technology Innovation Guidance Project, Inner Mongolia Autonomous Region (No. KCBJ2018040), National Nonprofit Industry Research (No. 201507002), the Fourth National Traditional Chinese Medicine Resources Survey Project (No. [2018]43), Science and Technology Planning Project of the Inner Mongolia Autonomous Region, China (No. 201701040), Standardization Project of Mongolian Medicine in Inner Mongolia Autonomous Region (No. 2018-008), Baotou Science and Technology Project (No.CX-2016-17), Scientific Research Foundation Project of Baotou Medical College (No. BYJJ-DF 2017-01), the Inner Mongolia Autonomous Region College Students Innovation and Entrepreneurship Training Program Project (No. 201710127010), Science and Technology Planning Project of the Inner Mongolia Autonomous Region (No. 201503020), China Agriculture Research System (No. CARS-21)

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Zhang, Ch., Yang, X., Wei, Jr. et al. Ethnopharmacology, Phytochemistry, Pharmacology, Toxicology and Clinical Applications of Radix Astragali. Chin. J. Integr. Med. 27, 229–240 (2021). https://doi.org/10.1007/s11655-019-3032-8

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  • DOI: https://doi.org/10.1007/s11655-019-3032-8

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