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Effect of Comprehensive Therapy based on Chinese Medicine Patterns on Self-Efficacy and Effectiveness Satisfaction in Chronic Obstructive Pulmonary Disease Patients

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Abstract

Objective

To evaluate the effect of comprehensive therapy based on Chinese medicine (CM) patterns on self-efficacy and satisfaction with its effectiveness in patients with chronic obstructive pulmonary disease (COPD).

Methods

A total of 216 patients were randomly divided into the trial group (n =108) and the control group (n=108) based on the stratified and block randomization design. Patients in the trial group were treated with conventional Western medicine combined with Bufei Jianpi Granules (补肺健脾颗粒), Bufei Yishen Granules (补肺益肾颗粒), and Yiqi Zishen Granules (益气滋肾颗粒) according to the CM patterns respectively, and patients in the control group were treated with conventional Western medicine. The COPD Self-Efficacy Scale (CSES) and the Effectiveness Satisfaction Questionnaire for COPD (ESQ-COPD) were employed in a 6-month treatment and in further 6 month follow-up visit.

Results

Among the 216 patients, 191 patients (97 in the trial group and 94 in the control group) fully completed the study. After 12-month treatment and follow-up, the mean scores of the trial group all continued to increase over time, which were significantly higher than those of the control group (P <0.05), and the improvement in the following trial group domain: negative affect domain (12.13%), intense emotional arousal domain (12.21%), physical exertion domain (11.72%), weather/environmental domain (13.77%), behavioral risk domain (7.67%) and total score (10.65%). The trial group also exhibited significantly higher mean scores in the ESQ-COPD (P <0.05) and the improvement in the following domain: capacity for life and work domain (30.59%), clinical symptoms domain (53.52%), effect of therapy domain (35.95%), convenience of therapy domain (35.54%), and whole effect domain (52.47%).

Conclusions

Bufei Jianpi Granules, Bufei Yishen Granules and Yiqi Zishen Granules can improve the self-efficacy and satisfaction of COPD patients.

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Acknowledgments

The authors acknowledge Prof. SUN Zi-kai of Jiangsu Provincial Hospital of Traditional Chinese Medicine, and Prof. ZHANG Wei of Affiliated Hospital of Shandong University of Traditional Chinese Medicine for the great assistance in the participation of the whole study.

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Authors and Affiliations

  1. Department of Respiratory, the First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450000, China

    Xue-qing Yu, Ming-hang Wang, Su-yun Li, Yang Xie & Hai-long Zhang

  2. Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China

    Xue-qing Yu, Ming-hang Wang, Jian-sheng Li, Su-yun Li, Yang Xie, Yun-ping Bai, Hai-long Zhang, Fan Cao & Cong-xia Hou

  3. Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, China

    Jian-sheng Li, Yun-ping Bai, Fan Cao & Cong-xia Hou

  4. Department of Respiratory, Henan Provincial People’s Hospital, Zhengzhou, 450003, China

    Li-jun Ma

Authors
  1. Xue-qing Yu
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  2. Ming-hang Wang
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  3. Jian-sheng Li
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  4. Su-yun Li
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Contributions

This project was initiated and developed by Li JS and Yu XQ. Li JS and Li SY were involved in the design of the study and the interventions of the protocol. Wang MH and Xie Y were involved in drafting and writing the manuscript. Yu XQ was involved in evaluating the data. Bai YP and Ma LJ were involved in coordinating the study and supervising the work. Zhang HL, Cao F, and Hou CX were involved in performing the study. All authors read and approved the fi nal manuscripts.

Corresponding author

Correspondence to Jian-sheng Li.

Additional information

Supported by the National Natural Science Foundation of China (No. 81473799), the Outstanding Youth Science and Technology Innovation Leader Program of Henan Province (No. 144100510010) and the National Key Technology R&D Program during the 12th Five-Year Plan Period (No. 2014BAI10B06)

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Yu, Xq., Wang, Mh., Li, Js. et al. Effect of Comprehensive Therapy based on Chinese Medicine Patterns on Self-Efficacy and Effectiveness Satisfaction in Chronic Obstructive Pulmonary Disease Patients. Chin. J. Integr. Med. 25, 736–742 (2019). https://doi.org/10.1007/s11655-017-2417-9

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  • DOI: https://doi.org/10.1007/s11655-017-2417-9

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