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A review on medicinal uses, analytical techniques and pharmacological activities of Strychnos nux-vomica Linn.: A concise report

Chinese Journal of Integrative Medicine (2017)Cite this article

Abstract

The purpose of this review is to provide comprehensive and relevant information on the utilization and pharmacological activities of Strychnos nux-vomica Linn. (Loganiaceae), used for the treatment of various diseases. Strychnos nux-vomica is an evergreen tree native to Southeast Asia and its dried seeds are used for the treatment of neurodisorders, arthritis and vomiting. The different use of this plant as herbal remedy in Chinese medicine is also reported in the literature. Strychnine and brucine are major pharmacologically active phytoconstituents of Strychnos nux-vomica, which are central nervous stimulant, but also found to be poisonous at high dosage. Owing to its diversity of phytoconstituents, it is used for treatment of various disorders. Pharmacologically it has been validated for its effect on inflammation, microbial infections, gastrointestinal problem, nervous system, bones cells, cardiovascular systems, cancer and blood glucose level. It also has antioxidant activity and antifeedant activity. Informations about Strychnos nux-vomica, compiled in the present review article could be useful to the researchers for the scientific validation of its traditional claim in the future.

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Authors and Affiliations

  1. GLA Institute of Pharmaceutical Research, Mathura, 281406, India

    Kanika Patel

  2. Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi, 221005, India

    Damiki Laloo, Gireesh Kumar Singh & Dinesh Kumar Patel

  3. Sri Kakatiya Institute of Pharmaceutical Sciences, Warangal, 506004, India

    Manoj Gadewar

  4. Department of Pharmacy, Galgotias University, Greater Noida, 203201, Uttar Pradesh, India

    Dinesh Kumar Patel

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  1. Kanika Patel
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  2. Damiki Laloo
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  3. Gireesh Kumar Singh
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Correspondence to Dinesh Kumar Patel.

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Patel, K., Laloo, D., Singh, G.K. et al. A review on medicinal uses, analytical techniques and pharmacological activities of Strychnos nux-vomica Linn.: A concise report. Chin. J. Integr. Med. (2017). https://doi.org/10.1007/s11655-016-2514-1

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Keywords

  • analytical technique
  • herbal medicine
  • pharmacological activity
  • phytochemistry
  • Strychnos nux-vomica