Clinical efficacy of Trigonella foenum graecum (Fenugreek) and dry cupping therapy on intensity of pain in patients with primary dysmenorrhea
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To determine the effificacy and safety of fenugreek seed and dry cupping on intensity of pain in primary dysmenorrhea.
Sixty patients with primary dysmenorrhea were enrolled in this prospective, open-labeled, randomized, standard-controlled study, conducted in the National Institute of Unani Medicine Hospital between February 2010 and April 2011. In group A (20 cases), 3 g powder of fenugreek seed (3 capsules, 1 g each) was given orally twice daily from day 1 to 3 of menstrual cycle. Group B (20 cases) received the same dose of fenugreek seed as group A along with dry cupping therapy [two 4.2-cm and one 2.5-cm cups (internal diameter)], which was applied below the umbilicus for 15 min on day 1 and day 3 of menstrual cycle for 3 consecutive months. The control group C (20 cases) was given mefenamic acid, 500 mg twice daily, on the same protocol. The reduction in menstrual pain intensity was measured with well validated Visual Analogue Scale and safety of fenugreek seed was evaluated by clinical examination and laboratory investigations.
Baseline characteristics and biochemical parameters were comparable and homogenous among all groups (P>0.05). The percentage reduction in lower abdominal pain was 66.89%, 66.49%, and 62.88% in A, B and C groups respectively at the end of the treatment. No adverse drug effects were noticed.
The fenugreek seed and dry cupping are effificacious, safe, cost effective, and well tolerated.
Keywordsrandomized standard-controlled trial Fenugreek (Hulba) Hijamat bila shurt (dry cupping) primary dysmenorrhea Visual Analogue Scale for pain intensity
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- 6.Daniels SE, Torri S, Desjardins PJ. Valdecoxib for treatment of primary dysmenorrhea. A randomized double blind comparision with placebo and naporoxin. J Gen Intern Med 2005;20:62–67.Google Scholar
- 7.Nejad VM, Asadipour M. Comparison of the effectiveness of fennel and mefenamic acid on pain intensity in dysmenorrhoea. East Med Health J 2006;12:423–427.Google Scholar
- 9.Sina I. Al Qanoon Fit Tib. Vol. (Urdu translation by Kantoori GH); New Delhi: Idara Kitabul Shifa; 2007:227,260, 291,312,331,340,342,374.Google Scholar
- 10.Hasan A. Kitabe Mukhtarate Fit Tib. Vol. New Delhi: Central Council for Research in Unani Medicine; 2005:140,141,292,781.Google Scholar
- 11.Khan A. Haziq. Pakistan: Madina Publishing Company; 1983:467–469.Google Scholar
- 12.Rushd I. Kitabul Kulliyat. Vol. New Delhi: Central Council for Research in Unani Medicine; 1987:56,87,114, 115,116,129,194,210,426.Google Scholar
- 13.Dawood MY. Primary dysmenorrhea advances in pathogenesis and management. ACOG 2006;108:428–441.Google Scholar
- 15.Anonymous. Hamdard pharmacopoeia of Eastern medicine. 2nd ed. Delhi: Sri Sat guru Publication; 1970:42,45,46.Google Scholar
- 16.Mohammed AH. Bustanul Mufradat. Delhi: Idarae Kitabus Shifa; 2002:572–573.Google Scholar
- 17.Ammar M, Alokbi Y, Mohammed A. Study of anti-inflammatory effect of some medicinal edible plants growing in Egypt. J Islamic Academy Sci 1997;10:113–122.Google Scholar
- 18.Malviya KG, Bhabulkar MW, Mali PY, Rangari D. Evaluation of analgesic potential of TFG seeds in rats by using tail flick method. J Pharm Res 2010;3:1680–1681.Google Scholar
- 19.Rohini R. Diuretic effect of Trigonella foenum graecum seed extracts. Int J Alternat Med 2009;6(2):1–4.Google Scholar
- 21.Qamri A, Muna G. Tarjumae Minhajul Ilaj. New Delhi: Central Council for Research in Unani Medicine; 2008:410.Google Scholar
- 22.Ullah K, Younis A, Wali M. An investigation into the effect of cupping therapy as a treatment for anterior knee pain and its potential role in health promotion. Int J Alternative Med 2007;4(1):1–9.Google Scholar
- 23.Sultana A, Rahman K, Farzana MUZN, Lone A. Efficacy of Hijamat bila Shurt (Dry Cupping) on intensity of pain in dysmenorrhoea: A preliminary study. Anc Sci Life 2010;30:20–23.Google Scholar
- 24.Vance AR, Hayes SH, Spielholz NI. Micro diathermy treatment for primary dysmenorrhea. Physl Ther 1996;76:1003–1008.Google Scholar
- 27.Shah MH. The general principles of Avicenna's Cannon of Medicine. Vol. I, 2nd ed. Karachi: Interservice Presco; 1998: 204, 408.Google Scholar
- 28.Wallis LA, Kasper AS, Brown W, Gordon G, Oril R, Barbo D. Textbook of women's health. Philadelphia: Lippincott Raven Publishers; 1998:471.Google Scholar
- 29.Guyton AC, Hall JE. Text book of medical physiology. 10th ed. Philadelphia: Saunder Publication; 2000:557.Google Scholar
- 30.Morrow C, Naumburg EH. Dysmenorrhea primary care. Clin OffPract 2009:36:19–32.Google Scholar
- 31.Yusuff MD. Primary dysmenorrhoea. Advances in pathogenesis and management. Obstet Gynocol 2006;2:428–433.Google Scholar