Application of photoluminescent bioceramic material for different chronic illnesses by selecting “trigger points” and “propagated sensation along meridians” phenomenon



To investigate the practicability on the processes of selecting “local tenderness skin points (trigger points)” and “propagated sensation along meridians” (PSM) phenomenon, and to find out the corresponding abnormal meridian channel in different illnesses.


Ten patients with different kinds of chronic illnesses were administered photoluminescent bioceramic material (PLB) irradiations on meridians. The processes of selecting trigger points and PSM phenomenon were carried out on 80% (8/10) of the cases to find out the corresponding abnormal meridian channel in different illnesses. There were 8 cases identified by trigger points selection; 3 cases identified by PSM; 2 were not identified by either trigger points or PSM. These 2 cases were tested with electrodermal measurements of the 24 Ryodoraku meridian points to select their corresponding abnormal meridian channels for PLB irradiations. Objective and subjective Clinical improvements after PLB irradations were recorded.


After PLB treatment, patients showed different noticeable improvements upon clinical observations. The most significant improvements were noticed shortly after subacute stage at 3–5 months durations of illnesses. Objective measurements showed a clinical improvement of 43.8%.


To explain our clinical observations, we simply deduced that PLB treatment induced or promoted fluid/water diffusion along meridian channels. There was a gradually dredging of the meridian channels thus relieving stagnation and a vital change in the flow of dynamic patterns of meridians. This conforms to, or validates, the old traditional Chinese theory of “Bu Tong Ze Tong” and “Tong Ze Bu Tong”, that is, where there is obstruction, there is pain; where there is no obstruction, there is no pain.

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  1. 1.

    Huang SM, Chien LY, Chang CC, Chen PH, Tai CJ. Abnormal gastroscopy findings were related to lower meridian energy. Evid Based Complement Alternat Med 2011;878391:1–7.

    Google Scholar 

  2. 2.

    Chen CW, Tai CJ, Choy CS, Hsu CY, Lin SL, Chan WP, et al. Wave-induced flow in meridians demonstrated using photoluminescentbioceramic material on acupuncture points. Evid Based Complement Alternat Med 2013;739293:1–11.

    Google Scholar 

  3. 3.

    Leung TK, Chang CP, Lee CM, Shen LK. Retrospective study of the total insertion period of peripherally inserted central catheter: discussion of anti-thrombogenic surface and other biomaterial requirements. Biomed Mater Eng 2006;16:183–188.

    CAS  PubMed  Google Scholar 

  4. 4.

    Leung TK, Yang JC, Lin YS. The physical, chemical and biological effects by room temperature ceramic far-infrared ray emitting material irradiated water: a pilot study. J Chin Chem Soc 2012;59:589–597.

    CAS  Article  Google Scholar 

  5. 5.

    Leung TK, Huang PJ, Chen YC, Lee CM. Physical chemical test platform for room temperature, far-infrared ray emitting ceramic materials (cFIR). J Chin Chem Soc 2011;58:653–658.

    CAS  Article  Google Scholar 

  6. 6.

    Lai CH, Leung TK, Peng CW, Chang KH, Lai MJ, Lai WF, et al. Effects of far-infrared irradiation on myofascial neck pain: a randomized, double-blind, placebo-controlled pilot study. J Alternat Complement Med 2014;20:123–129.

    Article  Google Scholar 

  7. 7.

    Leung TK, Lin YS, Chen YC, Shang HF, Lee YH, Su CH, et al. Immunomodulatory effects of far-infrared ray irradiation via increasing calmodulin and nitric oxide production in raw 264.7 macrophages. Biomed Eng 2009;21:317–323.

    CAS  Google Scholar 

  8. 8.

    Leung TK, Lin YS, Lee CM, Chen YC, Shang HF, Hsiao SY, et al. Direct and indirect effects of ceramic far infrared radiation on hydrogen peroxide scavenging capacity and on murine macrophages under oxidative stress. J Med Biol Eng 2011;31:345–351.

    Article  Google Scholar 

  9. 9.

    Leung TK, Shang HF, Chen DC, Chang TM, Hsiao SY, Ho CK, et al. Effects of far infrared rays on hydrogen peroxidescavenging capacity. Biomed Eng 2011;23:99–105.

    CAS  Google Scholar 

  10. 10.

    Leung TK, Chen CH, Lai CH, Lee CM, Chen CC, Yang JC, et al. Bone and joint protection ability of ceramic material with biological effects. Chin J Physiol 2012;55:47–54.

    CAS  PubMed  Article  Google Scholar 

  11. 11.

    Leung TK, Lee CM, Tsai SY, Chen YC, Chao JS. A pilot study of ceramic powder far-infrared ray irradiation (cFIR) on physiology: observation of cell cultures and amphibian skeletal muscle. Chin J Physiol 2011;54:247–254.

    PubMed  Article  Google Scholar 

  12. 12.

    Leung TK, Chen CH, Tsai SY, Hsiao G, Lee CM. Effects of far infrared rays irradiated from ceramic material (bioceramic) on psychological stress-conditioned elevated heart rate, blood pressure, and oxidative stress-suppressed cardiac contractility. Chin J Physiol 2012;55:323–330.

    PubMed  Article  Google Scholar 

  13. 13.

    Leung TK, Kuo CH, Lee CM, Kan NW, Hou CW. Physiological effects of bioceramic material on human, assessment by’ Harvard step’,’ resting metabolic rate’ (RMR) and’ treadmill running’ tests. Chin J physiol 2013;56:334–340.

    PubMed  Article  Google Scholar 

  14. 14.

    Leung TK, Lee CM, Lin MY, Ho YS, Chen CS, Wu CH, et al. Far infrared ray irradiation induces intracellular generation of nitric oxide in breast cancer cells. J Med Bio Eng 2009;29:15–18.

    Google Scholar 

  15. 15.

    Liau BY, Leung TK, Ou MC, Ho CK, Lin YS. Inhibitory Effects of far-infrared ray generating belt on primary dysmenorrheal. In J Photoen 2012;238468:1–6.

    Google Scholar 

  16. 16.

    Leung TK, Chan CF, Lai PS, Yang CH, Hsu CY, Lin YS. Inhibitory effects of far-infrared irradiation generated by ceramic material on murine melanoma cell growth. Int J Photoen 2012;646845:1–8.

    Article  Google Scholar 

  17. 17.

    Leung TK, Lee CM, Lin SL, Wu CH, Chiou JF, Huang PJ, et al. The protective effect of non-ionized radiation from far infrared ray emitting ceramic material (cFIR) against oxidative stress on human breast epithelial cell (MCF-10A). J Med Bio Eng 2014;34:69–75.

    Article  Google Scholar 

  18. 18.

    Lin YS, Lin MY, Leung TK, Liao CH, Huang TT, Huang HS. Property characterization and biological function of high far-infrared emitting ceramic powders. Instrum Today 2007;28:60–67.

    Google Scholar 

  19. 19.

    Leung TK, Lin JM, Chien HS, Day TC. Biological effects of melt spinning fabrics composed of 1% bioceramic material. Text Res J 2012;82:1121–1130.

    CAS  Article  Google Scholar 

  20. 20.

    Leung TK, Liu YC, Chen CH, Fang HN, Chen KC, Lee CM. In vitro cell study of the possible anti-inflammatory and pain relief mechanism of far-infrared ray emitting ceramic material. J Med Bio Eng 2013;33:79–184.

    Article  Google Scholar 

  21. 21.

    Lin SL, Chan WP, Choy CS, Leung TK. Enhancement of transdermal delivery of indomethacin and tamoxifen by farinfrared ray-emitting ceramic material (BIOCERAMIC): a pilot study. Transl Med 2013;3:1.

    CAS  Google Scholar 

  22. 22.

    Lin SL, Choy CS, Chan WP, Leung TK. Photoluminescence of bioceramic materials (PLB) as a complementary and alternative therapy for diabetes. Diabetes Metab 2013;4:10.

    Google Scholar 

  23. 23.

    Lin SL, Chan WP, Choy CS and Leung TK. Translating laboratory research of bioceramic material, application on computer mouse and bracelet, to ameliorate computer work-related musculoskeletal disorders. Transl Med 2013;4:1.

    Google Scholar 

  24. 24.

    Alvarez DJ, Rockwell PG. Trigger points: diagnosis and management. Am Fam Physic 2002;65:653–660.

    Google Scholar 

  25. 25.

    Simons DG, Hong CZ, Simons LS. Endplate potentials are common to midfibermyofacial trigger points. Am J Physiol Med Rehabil 2002;81:212–222.

    Article  Google Scholar 

  26. 26.

    Tough EA, White AR, Richards S, Campbell J. Variability of criteria used to diagnose myofascial trigger point pain syndrome-evidence from a review of the literature. Clin J Pain 2007;23:278–286.

    PubMed  Article  Google Scholar 

  27. 27.

    Melzack R, Stillwell DM, Fox EJ. Trigger points and acupuncture points for pain: correlations and implications. Pain 1977;3:32–38.

    Google Scholar 

  28. 28.

    Ward AA. Spontaneous electrical activity at combined acupuncture and myofascial trigger point sites. Acupunct Med 1996;14:75–79.

    Article  Google Scholar 

  29. 29.

    Castaneda-Hernandez GC, Paul BR. Volume transmission and pain perception. Sci World J 2003;3:677–683.

    Article  Google Scholar 

  30. 30.

    Zhang WB, Zhao Y, Kjell F. Understanding propagated sensation along meridians by volume transmission in peripheral tissue. Chin J Integr Med 2013;19:330–339.

    PubMed  Article  Google Scholar 

  31. 31.

    Zhang WB, Tian YY, Li H, Tian JH, Luo MF, Xu FL, et al. A discovery of low hydraulic resistance channel along meridians. J Acupunct Merid Stud 2008;1:20–28.

    Article  Google Scholar 

  32. 32.

    Lee MS, Kim YC, Moon SR, Shin BC, Jeong DM. Hydrodynamic analysis of waveforms induced by vibrational stimuli at meridian and non-meridian points. Am J Chin Med 2004;32:977–984.

    PubMed  Article  Google Scholar 

  33. 33.

    Lo S, Geng X, Gann D. Evidence for the existence of stable water-clusters at room temperature and normal pressure. Physics Letter A 2009;373:3872–3876.

    CAS  Article  Google Scholar 

  34. 34.

    Zhu ZX, Yan ZQ, Yu SZ, Zhang RX, Wang JY, Liu YM, et al. Studies on the phenomenon of latent propagated sensation along the channels. I. The discovery of a latent PSC and a preliminary study of its skin electrical conductance. Am J Chin Med 1981;9:216–24.

    CAS  PubMed  Article  Google Scholar 

  35. 35.

    Kuo TC, Lin CW, Ho FM. The soreness and numbness effect of acupuncture on skin blood flow. Am J Chin Med 2004;32:117–129.

    PubMed  Article  Google Scholar 

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Corresponding authors

Correspondence to Ting-Kai Leung 梁庭繼 or Wing P. Chan 陳榮邦.

Additional information

Supported by Taipei Medical University, Taiwan, China (No. TMU101-AE3-Y23)

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Leung, TK., Gasbarri, M., Tai, CJ. et al. Application of photoluminescent bioceramic material for different chronic illnesses by selecting “trigger points” and “propagated sensation along meridians” phenomenon. Chin. J. Integr. Med. (2015).

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  • Chinese medicine
  • photoluminescent bioceramic material
  • Ryodoraku method