Abstract
Objective
To observe the effect of Aike Mixture (艾可合剂, AKM) on prostatic inflammatory: infiltration in patients with chronic prostatitis type III A (III A-CP/CPPS) and evaluate its anti-inflammatory action.
Methods Methods
A total of 60 patients with III A-CP/CPPS suitable to operation and differentiated as Chinese medicine: Gan (肝)-qi stagnancy syndrome type were selected. They were assigned with the random number table to two groups equally. Before operation, the patients in the treated group were administered with Proscar combined with AKM, but those in the control group treated with Proscar only. Suprapubic transvesical prostatectomy was performed two weeks later, and prostatic pathological examination was conducted.
Results
Grading of: inflammatory cell infiltration showed that the mean grade in the treated group was 0.78±0.90 grades, which was sihnificantly lower than that in the control group 1.68±0.87 grades (P<0.05). However, the two groups were not different in the grades of fibroblast proliferation (1.50±0.70 grades vs 1.62±0.87 grades, P>0.05).
Conclusion
AKM could suppress the inflammatory cell infiltration, be an effective and safe remedy for the treatment of IIIA-CP/CPPS of Gan-qi stagnancy syndrome type, and worthy for spreading in clinical use.
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Supported by the Fujian Provincial Fund of Natural Sciences (No. C0440014)
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Zhang, Mj., Weng, Jf., Shi, Yl. et al. Effect of Aike Mixture (艾可合剂) on the inflammatory infiltration in patients with chronic prostatitis type III A. Chin. J. Integr. Med. 17, 26–30 (2011). https://doi.org/10.1007/s11655-011-0620-7
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DOI: https://doi.org/10.1007/s11655-011-0620-7