Abstract
Objective
To explore the effect of Chinese drugs for supporting essence and strengthening Pi (脾, SESP) combining with chemotherapy on the quality of life (QOL) in the children with solid tumor.
Methods
Using a digital table, 146 children with solid tumor were randomized into two groups, 77 in the control group and 69 in the treated group. They received conventional chemotherapy, but to the patients in the treated group, SESP were administered additionally. The patients’ scores of QOL and adverse reaction occurred were compared.
Results
The states in the treated group were superior to those in the control group. Statistical analysis showed that in the fifirst year, the two groups were different in terms of somatic function, systemic symptoms, and general status (P<0.05) and also in the occurrence of adverse reaction (P<0.01). In the second year, the difference was shown in aspects of somatic function and adverse reaction occurrence (P<0.05).
Conclusion
Chinese drugs for SESP combining with chemotherapy could raise tumor patients’ QOL by improving their somatic function and clinical symptoms.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Zhang LH, Wang FZ, Liu GR. Clinical observation on quality of life in patients with advanced non-small lung cancer treated by Aidi Injection combined with chemotherapy. Chin J Pract Intern Med (Chin) 2003;23:427–428.
Chen ZD. Improvement on evaluation criteria of clinical efficacy and side effects of cance. Mod Pract Med (Chin) 2004;16:253–255.
Gao JC, Wang YP, eds. Modern pediatric oncology. Shanghai: Fudan Press; 2003:839–840.
Varni JW, Seid M, Kninght TS, Uzark K, Szer IS. The pedsQL 4.0 generic core scales: sensitivity, responsiveness, and impact on clinical decision-making. J Behav Med 2002;25:175–193.
Lin HS, Li HQ, Piao BK. Evaluation methods of Chinese medicine in treatment of advanced lung cancer. Bull Chin Cancer (Chin) 2000;9:354–355.
He XM, Fan JC, Zhu CM. Investigation on the quality of lifefor patients with malignant tumors. Chin J Hosp Adm (Chin) 2006;22:192–196.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Shi, X., Tian, L., Zhu, Xd. et al. Effect of Chinese drugs combining with chemotherapy on quality of life in 146 children with solid tumor. Chin. J. Integr. Med. 17, 31–34 (2011). https://doi.org/10.1007/s11655-011-0608-3
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11655-011-0608-3