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Treatment of inflammatory bowel disease with Chinese drugs administered by both oral intake and retention enema

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Objective

To study the clinical effect of Chinese drugs administered by both oral intake and retention enema on inflammatory bowel diseases (IBD).

Methods

Adopting a randomized controlled design, 78 patients were assigned to three groups: 26 patients in group A treated with Chinese drugs given by both oral intake and retention enema, 27 in group B with Chinese drugs given by retention enema only, and 25 in group C with given Western medicine. The changes before and after a 30-day treatment of the patients’ symptoms (including diarrhea, abdominal pain, mucous or pus-bloody stool), colonoscopic examination scores and histopathology of the colonic membrane were observed.

Results

Group A showed the best outcomes in all the aspects of clinical comprehensive effectiveness. Improvements in the main symptoms, colonoscopic scores and histopathology of the colonic membrane were significantly different from those in groups B and C, respectively (P<0.05). Meanwhile comparisons between groups B and C showed insignificant differences (P>0.05); group B was better in ameliorating tenesmus (P<0.05).

Conclusion

Through the use of Chinese drugs administered by both oral intake and retention enema to treat IBD, which combined external-internal therapies for both overall regulation and local managment, it was confirmed that the Chinese medicine could embody the therapeutic principle of attending to both disease-diagnosis and syndrome-differentiation.

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References

  1. Wang FY. Effect of incidence, prevalence and environmental factors in inflammatory bowel disease. Chin J Social Med (Chin) 2007;24:138–139.

    CAS  Google Scholar 

  2. Lakatos PL. Recent trends in the epidemiology of inflammatory bowel disease, Up or down? World J Gastroenterol 2006;12:6102–6108.

    PubMed  Google Scholar 

  3. Chen ZS, Wei BH, Chen ZM. Diagnosis, syndrome differentiation and efficacy standards of integrative medicine in chronic non-specific ulcerative colitis (trial). Chin J Integr Tradit West Med (Chin) 1994;14:239–240.

    Google Scholar 

  4. Chinese Society of Gastroenterology. Suggestion on diagnosis and treatment standard of inflammatory bowel disease. Chin J Dig (Chin) 2001;21:56–59.

    Google Scholar 

  5. Xie JL, Steven HI. Cancer in inflammatory bowel disease. World J Gastroenterol 2008;14:378–389.

    Article  CAS  PubMed  Google Scholar 

  6. Ran ZH, Shen J. New concepts in the treatment of inflammatory bowel disease. Chin J Gastroenterol (Chin) 2009;14:69–73.

    Google Scholar 

  7. Zhao RR, ed. Clinical pharmacy. (1st ed). Beijing: Beijng Publishing Group LTD.; 2000:634–635.

    Google Scholar 

  8. Ling XS, Wang XK, Chen DS. Internal medicine of integrative medicine. 1st ed. Beijing: China Press of Traditional Chinese Medicine; 2001:466.

    Google Scholar 

  9. Wu J, Shan ZW. Retrospective analysis of 115 cases IBD patients treated and etiopathology by TCM view. Pract Clini J Integr Tradit Chin West Med (Chin) 2004;4:4–6

    Google Scholar 

  10. Yang QX, Yang JY, Qu CF, Li DJ, Wang H, Xi XY, et al. Enflunce of membranous milkvetch root on guina pig of type I hypersensitivity. Chin J Microecol (Chin) 2002;14:17–18.

    Google Scholar 

  11. Shi YQ. Current research in cytokines of immune regulation and inflammatory bowel disease. Med J Communications (Chin) 2009;23:310–313.

    Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Digestive Diseases, The 4th Hospital Affiliated to Harbin Medical University, Harbin, 150001, China

    Xiao-hua Ling  (凌霄华), Xin Yu  (于 欣), Yu Hong  (洪 钰) & Xiao-ming Yang  (杨小明)

  2. Department of Pathology, the 4th Hospital Affiliated to Harbin Medical University, Harbin, 150001, China

    Cheng-yi Hu  (胡成乙)

  3. The second Affiliated Hospital of Harbin Medical University, Harbin, 150001, China

    De-jun Kong  (孔德军)

Authors
  1. Xiao-hua Ling  (凌霄华)
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  2. Xin Yu  (于 欣)
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  3. De-jun Kong  (孔德军)
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  4. Cheng-yi Hu  (胡成乙)
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  5. Yu Hong  (洪 钰)
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  6. Xiao-ming Yang  (杨小明)
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Corresponding author

Correspondence to Xiao-hua Ling  (凌霄华).

Additional information

Supported by Heilongjiang Administration of Traditional Chinese Medicine

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Ling, Xh., Yu, X., Kong, Dj. et al. Treatment of inflammatory bowel disease with Chinese drugs administered by both oral intake and retention enema. Chin. J. Integr. Med. 16, 222–228 (2010). https://doi.org/10.1007/s11655-010-0222-0

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  • DOI: https://doi.org/10.1007/s11655-010-0222-0

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