Chinese Journal of Integrative Medicine

, Volume 16, Issue 2, pp 188–192 | Cite as

Advance of studies on anti-atherosclerosis mechanism of berberine

  • Min Wu (吴 敏)
  • Jie Wang (王 阶)Email author
  • Long-tao Liu (刘龙涛)


Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness, purging fire to eliminate toxin. Berberine is the main alkaloid of Coptis Chinensis, and, recent researches showed that berberine had the effect of anti-atherosclerosis. This paper reviewed the anti-atherosclerosis mechanism of berberine, which may be related to regulating lipids, anti-inflammation, decompression, reducing blood sugar, and inhibiting vascular smooth muscle cell proliferation.


Coptis Chinensis berberine atherosclerosis 


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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Min Wu (吴 敏)
    • 1
  • Jie Wang (王 阶)
    • 1
    Email author
  • Long-tao Liu (刘龙涛)
    • 2
  1. 1.China Academy of Chinese Medical SciencesBeijingChina
  2. 2.Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijingChina

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