Skip to main content
SpringerLink
Log in

Thinking on how to construct the system of Chinese medicine efficacy evaluation for coronary heart disease angina pectoris

  • Academic Exploration
  • Published:
Chinese Journal of Integrative Medicine Aims and scope Submit manuscript

Abstract

The existing efficacy evaluation for coronary heart disease (CHD) angina pectoris does not demonstrate the characteristics and advantages of Chinese medicine (CM), so a new system of efficacy evaluation which can scientifically and systematically reflect the specific features of CM needs to be urgently set up. Based on wide references of efficacy evaluations of CHD angina pectoris from our country and abroad, and considering the general acceptance by academic circles and demonstration of the characteristics of CM, this paper tries to set up a new index system of efficacy evaluation, combining both disease and syndrome differentiation for CHD angina pectoris. This paper also offers some explorations based on the results of clinical trials. The system is composed of six aspects, including efficacy evaluation of “disease”, syndrome factors and main endpoints (the incidence of important clinical events), as well as patient reported outcomes, safety evaluation and medical economics.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ministry of Health, PR China. Guiding principle of clinical research on new drugs of traditional Chinese medicine. Beijing: China Medic-Pharmaceutical Sciences and Technology Publishing House; 2002:68–73.

    Google Scholar 

  2. State Administration of Traditional Chinese Medicine. Standard of syndrome diagnosis and curative effect of traditional Chinese medicine. Nanjing: Nanjing University Publishing House; 1994:204.

    Google Scholar 

  3. Shen SG, Yao JC. Chinese medicine diagnosis and efficacy evaluation for cornoary heart disease angina pectoris. Chin J Tradit Chin Med Pharm (Chin) 2004;19:581–583.

    Google Scholar 

  4. Zhao DH, Jiang BQ. European guidance on clinical investigation on medicinal products for the treatment of angina. Chin J Clin Pharm (Chin) 1999;15:151–153.

    Google Scholar 

  5. Wang J, Li J, Yang G, Yao KW. Technical lines and methods of establishing syndrome diagnostic measuringscale for CAD angina pectoris. World Sci Techno-Modern Tradit Chin Med (Chin) 2007;9:13–17.

    Google Scholar 

  6. Sun ZQ. Comprehensive evaluation methods of medical and application. Beijing: Chemical Industry Publishing House, 2006:49–50.

    Google Scholar 

  7. Dai RW, Cao LB. Research of hall for workshop of metasynthetic engineering. J Manage Sci Chin (Chin) 2002;5(3):11–17.

    Google Scholar 

  8. Fleming TR, De Mets DL. Surrogate endpoints in clinical trials: are we being misled? Ann Intern Med 1996;125:605–613.

    CAS  PubMed  Google Scholar 

  9. Song J, Chen KJ. Pondering over some problems in evaluating clinical efficacy of Chinese medicine. Chin J Integr Tradit West Med (Chin) 2003;23:564–565.

    Google Scholar 

  10. The World Health Organization Quality of Life assessment (WHOQOL): position paper from the World Health Organization. Soc Sci Med 1995;41:1403–1409.

    Article  Google Scholar 

  11. U.S. Department of Health and Human Services FDA Center for Drug Evaluation and Research; U.S. Department of Health and Human Services FDA Center for Biologics Evaluation and Research; U.S. Department of Health and Human Services FDA Center for Devices and Radiological Health Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance. 2006;4:79.

    Google Scholar 

  12. Wu XF, Lai SL, Liang WX. Choice and application of the outcome indexes for clinical effectiveness assessment of traditional Chinese medicine. J Guangzhou Univ Tradit Chin Med (Chin) 2002;19:251–255.

    Google Scholar 

  13. Jin L, Wang J, Wang T. Evaluation on effects of disassembled formulas of Xuefu Zhuyu Decoction for treatment of angina pectoris using Seattle Angina Questionnaire. Chin J Integr Med (Chin) 2007;27:18–20.

    CAS  Google Scholar 

  14. Na KX, Yu P. Reasonable application of nitrate esters. Intern J Emerg Crit Care Med (Chin) 2006;3:1379–1381.

    Google Scholar 

  15. Wang J, Jin L. A clinical study of separated complex prescriptions based on disease and syndrome. World Sci Technol-Modern Tradit Chin Med (Chin) 2007;9:16–20.

    CAS  Google Scholar 

  16. Wang J, He QY, Xin YW, Li HX, Wang SH, Fang YT. Health economics of clinical angina pectoris. World Sci Technol-Modern Tradit Chin Med (Chin) 2008;10:17–21.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China

    Jie Wang  (王 阶) & Qing-yong He  (何庆勇)

Authors
  1. Jie Wang  (王 阶)
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Qing-yong He  (何庆勇)
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Qing-yong He  (何庆勇).

Additional information

Supported by the National Basic Research Program of China (973 Program, No. 2003CB517103) and the Natural Science Foundation of Beijing (No. 7062058)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wang, J., He, Qy. Thinking on how to construct the system of Chinese medicine efficacy evaluation for coronary heart disease angina pectoris. Chin. J. Integr. Med. 16, 75–78 (2010). https://doi.org/10.1007/s11655-010-0075-2

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11655-010-0075-2

Keywords

Search

Navigation