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Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects

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Abstract

Objective

To determine the anti-obesity effects of oolong tea on diet-induced overweight or obesity.

Methods

A total of 8 g of oolong tea a day for 6 weeks was ingested by 102 diet-induced overweight or obese subjects. The body fat level of the subjects was determined at the same time by taking body weight, height and waist measurements. The thickness of the subcutaneous fat layer was also determined on the abdomen 3 cm to the right of the navel by the ultrasonic echo method. On the other hand, effects of oolong tea ingestion on plasma triglyceride (TG) and total cholesterol (TC) were determined. Inhibitions of pancreatic lipase by oolong tea extract and catechins in vitro were also determined.

Results

A total of 70% of the severely obese subjects did show a decrease of more than 1 kg in body weight, including 22% who lost more than 3 kg. Similarly, 64% of the obese subjects and 66% of the overweight subjects lost more than 1 kg during the experiment, and the subcutaneous fat content decreased in 12% of the subjects. The correlation between weight loss and subcutaneous fat decrease in men (r=0.055) was obviously lower than that in women (r=0.440, P<0.01). Body weight loss was signifificantly related to the decrease of the waist size in men (r=0.730, P<0.01) and women (r=0.480, P<0.01). Also, the correlation between subcutaneous fat reduction and decreased waist size was signifificant in women (r=0.554, P<0.01), but not in men (r=0.050, P>0.05). Moreover, the plasma levels of TG and TC of the subjects with hyperlipidemia were remarkably decreased after ingesting oolong tea for 6 weeks. In vitro assays for the inhibition of pancreatic lipase by oolong tea extract and catechins suggest that the mechanism for oolong tea to prevent hyperlipidemia may be related to the regulative action of oolong tea catechins in lipoprotein activity.

Conclusions

Oolong tea could decrease body fat content and reduce body weight through improving lipid metabolism. Chronic consumption of oolong tea may prevent against obesity.

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References

  1. Abelson P, Kennedy D. The obesity epidemic. Science 2004;304:1413.

    Article  PubMed  CAS  Google Scholar 

  2. Hill JO, Melanson EL, Wyatt HT. Dietary fat intake and regulation of energy balance: Implications for obesity. J Nutr 2000; 130: 284S–288S.

    PubMed  CAS  Google Scholar 

  3. Manson JE, Colditz GA, Stampfer MJ, Willett WC, Rosner B, Monson RR, et al. A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med 1990;322:882–889.

    PubMed  CAS  Google Scholar 

  4. Astrup A, Buemann B, Western P, Toubro S, Raben A, Christensen NJ. Obesity as an adaptation to a high-fat diet: evidence from a cross-sectional study. Am J Clin Nutri 1994;59:350–355.

    CAS  Google Scholar 

  5. Campfield LA, Smith FJ, Burn P. Strategies and potential molecular targets for obesity treatment. Science 1998; 280:1383–1387.

    Article  PubMed  CAS  Google Scholar 

  6. Bray GA, Greenway FL. Current and potential drugs for treatment of obesity. Endocr Rev 1999;20:805–875.

    Article  PubMed  CAS  Google Scholar 

  7. Han LK, Takaku T, Li J, Kimura Y, Okuda H. Anti-obesity action of oolong tea. Int J Obes 1999;23:98–105.

    Article  CAS  Google Scholar 

  8. Kuo KL, Weng MS, Chiang CT, Tsai YJ, Lin-Shiau SY, Lin JK. Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh, and green tea leaves in rats. J Agric Food Chem 2005; 53:489–489.

    Google Scholar 

  9. Rumpler W, Seale J, Clevidence B, Judd J, Wiley E, Yamamoto S, et al. Oolong tea increases metabolic rate and fat oxidation in men. J Nutr 2001;131:2848–2852.

    PubMed  CAS  Google Scholar 

  10. Okuda H, Han LK. Medicinal plant and its related metabolic modulators. Nippon Yakurigaku Zasshi 2001;118:347–351.

    PubMed  CAS  Google Scholar 

  11. Davies MJ, Judd JT, Baer DJ, Clevidence BA, Paul DR, Edwards AJ, et al. Black tea consumption reduces total and LDL cholesterol in mildly hypercholesterolemic adults. J Nutr 2003;133:3298–3302.

    Google Scholar 

  12. Khosla T, Lowe CR. Indices of obesity derived from body weight and height. Br J Prev Soc Med 1967;21:122–128.

    PubMed  CAS  Google Scholar 

  13. WHO Physical Status: The use and interpretation of anthropometry. Report of a WHO expert committee Geneva: World Health Organization Technical Report Seriels; 1995:854.

  14. WHO. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation on obesity, Geneva 3–5, June 1997. World Health Organization Techinical Report Series. Vol. 210. Geneva: World Health Organization;1997:1–276.

    Google Scholar 

  15. Xie B, Shi H, Chen Q, Ho CT. Antioxidant properties of fractions and polyphenol constituents from green, oolong and black teas. Proc Natl Sci Counc Repub China (B) 1993;17:77–84.

    CAS  Google Scholar 

  16. Bitou N, Ninomiya M, Tsujita T, Okuda H. Screening of lipase inhibitors from marine algae. Lipids 1999;34:441–445.

    Article  PubMed  CAS  Google Scholar 

  17. Golor G, Yamashita K, Koner W, Hagenmaier H, Neubert D. Kinetics and inductive potency of 1, 2, 3, 4, 6, 7, 8-heptachlorodibenzo-p-dioxin (H7CDD) in rats. Life Sci 2001;69:493–508.

    Article  PubMed  CAS  Google Scholar 

  18. Saris W. Sugars, energy metabolism, and body weight control. Am J Clini Nutri 2003;78:850–857.

    Google Scholar 

  19. Iwata K, Inayama T, Miw S, Kawaguchi K, Koike G. Effect of oolong tea on plasma lipids and lipoprotein lipase activity in young women. J Jpn Soc Nutr Food Sci 1991;44:251–259.

    CAS  Google Scholar 

  20. Lin YS, Tsai YJ, Tsay JS, Lin JK. Factors affecting the levels of tea polyphenols and caffeine in tea leaves. J Agric Food Chem 2003;51:1864–1873.

    Article  PubMed  CAS  Google Scholar 

  21. Dulloo AG, Dure C, Rohrer D, Girardier L, Mensi N, Fathi M. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutri 1999;70:1040–1045.

    CAS  Google Scholar 

  22. Bianchi CP. Cellular pharmacology of contraction of skeletal muscle. In: Narahashi T, ed. Cellular pharmacology of excitable tissues. Charles C: Thomas Publisher;1975:485–519.

    Google Scholar 

  23. Arciero PJ, Gardner AW, Calles-Escandon J, Benowitz NL, Poehlman ET. Effects of caffeine ingestion on NE kinetics, fat oxidation, and energy expenditure in younger and older men. Am J Physiol 1995;268:E1192–E1198.

    PubMed  CAS  Google Scholar 

  24. Couturier C, Janvier B, Girlich D, Bereziat G, Andreani-Mangeney M. Effects of caffeine on lipoprotein lipase gene expression during the adipocyte differentiation process. Lipids 1998;33:455–460.

    Article  PubMed  CAS  Google Scholar 

  25. Mulder H, Holst LS, Svensson H, Degerman E, Sundler F, Ahren B. Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells. Diabetes 1999;48: 228–232.

    Article  PubMed  CAS  Google Scholar 

  26. Kao YH, Hiipakka RA, Liao S. Modulation of obesity by green tea catechins. Am J Clin Nutr 2000;72:1232–1233.

    PubMed  CAS  Google Scholar 

  27. Watanabe J, Kawabata J, Niki R. Isolation and identification of acetyl-CoA carboxylase inhibitors from green tea (Camellia sinensis). Biosci Biotechnol Biochem 1998;62:532–534.

    Article  PubMed  CAS  Google Scholar 

  28. Nakahara K, Izumi R, Kodama T, Kiso Y, Tanaka T. Inhibition of postprandial hyperglycaemia by oolong tea extract (OTE). Phytother Res 1994;8:433–435.

    Article  Google Scholar 

  29. Han LK, Kimura Y, Kawashima M, Takaku T, Taniyama T, Hayashi T, et al. Anti-obesity effects in rodents of dietary teasaponin, a lipase inhibitor. Int J Obes 2001;25:1459–1464.

    Article  CAS  Google Scholar 

  30. Inui Y, Kawata S, Matsuzawa Y, Tokunaga K, Fujioka A, Tamura S, et al. Increased level of apolipoprotein B mRNA in the liver of ventromedial hypothalamus lesioned obese rats. Biochim Biophys Res Commun 1989;163:1107–1112.

    Article  CAS  Google Scholar 

  31. Wang SR, Infante J, Catala D, Petit D, Bonnefis MT, Infante R. Lipid and lipoprotein synthesis in isolated and cultured hepatocytes from lean and obese Zucker rats. Biochim Acta 1989;1002:302–311.

    CAS  Google Scholar 

  32. Garrison RJ, Wilson PW, Castelli WP, Feinleib M, Kannel WB, McNamara PM. Obesity and lipoprotein cholesterol in the Framingham offspring study. Metabolism 1980;29:1053–1060.

    Article  PubMed  CAS  Google Scholar 

  33. Chisaka T, Matsuda H, Kubomura Y, Mochizuki M, Yamahara J, Fujimura H. The effect of crude drugs on experimental hypercholesteremia: Mode of action of (-)-epigallocatechin gallate in tea leaves. Chem Pharm Bull 1988;36:227–233.

    PubMed  CAS  Google Scholar 

  34. Ikeda I, Imasato Y, Sasaki E, Nakayama M, Nagao T, Takeo T, et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochim Biophys Acta 1992;1127:141–146.

    PubMed  CAS  Google Scholar 

  35. Okuda T, Kimura Y, Yoshida T, Hatano T, Okuda H, Arichi S. Studies on the activities of tannins and related compounds from medicinal plants and drugs. I. Inhibitory effects on lipid peroxdation in mitochondria and microsomes of liver. Chem Pharm Bull 1983;31:1625–1631.

    PubMed  CAS  Google Scholar 

  36. Muramatsu K, Fukuyo M, Hara Y. Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats. J Nutr Sci Vitaminol 1986;32:613–622.

    PubMed  CAS  Google Scholar 

  37. Matsuda H, Chisaka T, Kubomura Y, Yamahara J, Sawada T, Fujimura H. Effects of crude drugs on experimental hypercholesterolemia. I. Tea and its active principles. J Ethnopharmacol 1986;17:213–224.

    Article  PubMed  CAS  Google Scholar 

  38. Hasegawa N, Yamda N, Mori M. Powdered green tea has antilipogenic effect on Zucker rats fed a high-fat diet. Phytother Res 2003;17:477–480.

    Article  PubMed  Google Scholar 

  39. Matsuzawa Y. Life style-related disease. Nippon Rinsho 2001;59:188–194.

    PubMed  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. School of Traditional Chinese Materia Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China

    Rong-rong He  (何蓉蓉) & Xin-sheng Yao  (姚新生)

  2. Fujian Institute of Traditional Chinese Medicine, Fuzhou, 350003, China

    Ling Chen  (陈 玲) & Bing-hui Lin  (林炳辉)

  3. Products Development Center, Suntory Ltd., 5-2-5, Yamazaki, Shimamoto-cho, Mishima-gun, Osaka, 618-0001, Japan

    Yokichi Matsui  (松井阳吉)

  4. Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, 510632, China

    Xin-sheng Yao  (姚新生) & Hiroshi Kurihara  (栗原 博)

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  1. Rong-rong He  (何蓉蓉)
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  2. Ling Chen  (陈 玲)
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Correspondence to Hiroshi Kurihara  (栗原 博).

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He, Rr., Chen, L., Lin, Bh. et al. Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects. Chin. J. Integr. Med. 15, 34–41 (2009). https://doi.org/10.1007/s11655-009-0034-8

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  • DOI: https://doi.org/10.1007/s11655-009-0034-8

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