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Clinical study on the treatment of premature ejaculation by Uighur medicine Gu-jing-mai-si-ha Tablet (固精麦斯哈片)

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Abstract

Objective

To observe the effect of Uighur medicine Gu-jing-mai-si-ha Tablet (固精麦斯哈片, GJMSHT) for treatment of premature ejaculation (PE) and to explore part of its mechanism.

Methods

The condition of patients was scored by related questionnaire, and the intravaginal ejaculation latency time (IELT) was observed before and after GJMSHT treatment, with the blood levels of nitric oxide (NO) and prostaglandin F2α (PGF2α) detected in PE patients as well. The results were compared with those in the control group.

Results

After treatment, the scores of PE and IELT, as well as the levels of NO and PGF2α, all increased significantly compared to those before treatment in the treated group (P<0.01), while in the control group, all the parameters were insignificantly changed (P>0.05). Therefore, the difference of these parameters between the two groups after treatment all showed statistical significance (P<0.01).

Conclusion

GJMSHT could treat PE effectively, its mechanism is possibly by strengthening the coordination of the related smooth muscles through increasing the blood levels of NO and PGF2α, and the endurance of patients to the cavitary effect of prostatico-urethral pressure, thus postponing the arrival of urgent ejaculatory feeling.

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Authors and Affiliations

  1. The 5th Affiliated Hospital of Xinjiang Medical University, Urumuqi, 830011, China

    Song Guo-hong  (宋国宏), Geng Jin-cheng  (耿进成), Feng Lian-cheng  (冯连成) & Liu Jun  (刘 军)

  2. Xinjiang Medical University, China

    Halmurat Upur  (哈木拉提·吾甫尔) & Yilihamujiang shabi  (伊力哈木江·沙比提)

  3. The Affiliated TCM Hospital, Xinjiang Medical University, China

    Ma Chao  (马 超)

Authors
  1. Song Guo-hong  (宋国宏)
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  2. Halmurat Upur  (哈木拉提·吾甫尔)
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  3. Geng Jin-cheng  (耿进成)
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  4. Feng Lian-cheng  (冯连成)
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  5. Yilihamujiang shabi  (伊力哈木江·沙比提)
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  6. Ma Chao  (马 超)
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  7. Liu Jun  (刘 军)
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Corresponding author

Correspondence to Halmurat Upur  (哈木拉提·吾甫尔).

Additional information

Supported by the Program of Developing Modern Uighur Medicine and Setting an Example Project of High-Tech Industries (No. 2002-422)

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Song, Gh., Halmurat, U., Geng, Jc. et al. Clinical study on the treatment of premature ejaculation by Uighur medicine Gu-jing-mai-si-ha Tablet (固精麦斯哈片). Chin. J. Integr. Med. 13, 185–189 (2007). https://doi.org/10.1007/s11655-007-0185-7

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  • DOI: https://doi.org/10.1007/s11655-007-0185-7

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