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Diagnostisches und therapeutisches Vorgehen beim Nebennierenrindenkarzinom

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best practice onkologie Aims and scope

Zusammenfassung

Das Nebennierenrindenkarzinom ist ein seltenes, aber aggressives Malignom mit i. Allg. schlechter Prognose. Internationale Kooperationen der letzten 10 Jahre haben es ermöglicht, das diagnostische Vorgehen zu standardisieren und therapeutische Strategien zu evaluieren. Die Therapie des Nebennierenrindenkarzinoms ist interdisziplinär und multimodal, jedoch gibt es nur wenige Fortschritte in der Entwicklung neuer effektiver Therapien. Die vollständige chirurgische Resektion ist die einzige kurative Option. Die Behandlung mit Mitotan besitzt sowohl in der adjuvanten Situation als auch im fortgeschrittenen Stadium eine herausragende Bedeutung.

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Correspondence to Marcus Quinkler.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. T. Kienitz und M. Quinkler haben an einer Studie, gesponsert von Astellas Pharma, zur Wirkung des IGF1-Rezeptor-Antagonisten OSI-906 teilgenommen. M. Quinkler wurde für einzelne Studienprojekte von HRA Pharma und Pfizer unterstützt.

T. Kienitz, N. Rayes und M. Quinkler geben an, dass kein Interessenkonflikt bezüglich dieses Artikels besteht.

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Kienitz, T., Rayes, N. & Quinkler, M. Diagnostisches und therapeutisches Vorgehen beim Nebennierenrindenkarzinom. best practice onkologie 10, 42–49 (2015). https://doi.org/10.1007/s11654-014-0520-3

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