Cancer of unknown primary (CUP; Krebs bei unbekanntem Primärtumor) ist eine onkologische Standarddiagnose mit klarem Diagnostik- und Therapiealgorithmus. Die Diagnostik hat die Etablierung einer Arbeitsdiagnose zum Ziel. Sie stützt sich auf die Klinik sowie bildgebende, histologische und immunhistologische Analysen. Die Therapie sollte nicht durch repetitive Diagnostik verzögert werden. Wichtig ist die Identifikation der ca. 20 % aller CUP-Patienten mit günstiger Prognose und z. T. kurativem Therapieansatz.
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Interessenkonflikt. T. Weber, G. Hübner, I. Wildfang und H.-J. Schmoll geben an, dass kein Interessenkonflikt besteht.
Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Weber, T., Schmoll, H.J., Hübner, G. et al. Cancer of unknown primary (CUP). best practice onkologie 9, 22–30 (2014). https://doi.org/10.1007/s11654-013-0116-3
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DOI: https://doi.org/10.1007/s11654-013-0116-3