Impianti e sostituti meniscali

  • Matteo OlivieriEmail author
  • Diana Chicon Paez
  • Luca Turelli

Meniscal implants and substitutes


When meniscal lesions occur, preservation of meniscal tissue and restoration of the normal meniscal biomechanics is imperative to avoid early knee osteoarthritis; however, current surgical treatments for meniscal tears suffer from subsequent cartilage degeneration and inconsistent post-treatment results. When meniscal replacement is indicated, the desired implant should be chondroprotective; nevertheless, long-term effects of meniscal transplantation in protecting the articular cartilage have not been fully elucidated as yet. To date, three clinical scaffolds that allow 3-dimensional reconstruction of the meniscal structure (Menaflex CMI, Actifit® scaffold and NUsurface® Meniscus Implant) are available on the market for use, but additional data are needed to properly evaluate their safety and effectiveness.


Conflitto di interesse

Gli autori Matteo Olivieri, Diana Chicon Paez e Luca Turelli dichiarano di non avere alcun conflitto di interesse.

Consenso informato e conformità agli standard etici

Tutte le procedure descritte nello studio e che hanno coinvolto esseri umani sono state attuate in conformità alle norme etiche stabilite dalla dichiarazione di Helsinki del 1975 e successive modifiche. Il consenso informato è stato ottenuto da tutti i pazienti inclusi nello studio.

Human and Animal Rights

L’articolo non contiene alcuno studio eseguito su esseri umani e su animali da parte degli autori.


  1. 1.
    Annandale T (1889) Excision of the internal semilunar cartilage, resulting in perfect restoration of the joint-movements. Br Med J 1(1467):291–292 CrossRefGoogle Scholar
  2. 2.
    King D (1936) The function of the semilunar cartilages. J Bone Jt Surg 18-B:1069–1076 Google Scholar
  3. 3.
    Fairbank TJ (1948) Knee joint changes after meniscectomy. J Bone Jt Surg, Br Vol 30B(4):664–670 CrossRefGoogle Scholar
  4. 4.
    Baratz ME, Fu FH, Mengato R (1986) Meniscal tears: the effect of meniscectomy and of repair on intraarticular contact areas and stress in the human knee. A preliminary report. Am J Sports Med 14(4):270–275 CrossRefGoogle Scholar
  5. 5.
    Allen PR, Denham RA, Swan AV (1984) Late degenerative changes after meniscectomy. Factors affecting the knee after operation. J Bone Jt Surg, Br Vol 66(5):666–671 CrossRefGoogle Scholar
  6. 6.
    Lohmander LS, Englund PM, Dahl LL, Roos EM (2007) The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med 35(10):1756–1769 CrossRefGoogle Scholar
  7. 7.
    Guo W, Liu S, Zhu Y et al. (2015) Advances and prospects in tissue-engineered meniscal scaffolds for meniscus regeneration. Stem Cells Int 2015:13 Google Scholar
  8. 8.
    Shimomura K, Hamamoto S, Hart DA et al. (2018) Meniscal repair and regeneration: current strategies and future perspectives. J Clin Orthop Trauma 9(3):247–253 CrossRefGoogle Scholar
  9. 9.
    De Coninck T, Verdonk P, Verstraete K (2016) MR-imaging of meniscal substitution. J Belg Soc Radiol 100(1):90 CrossRefGoogle Scholar
  10. 10.
    Doral MN, Bilge O, Huri G et al. (2018) Modern treatment of meniscal tears. EFORT Open Rev 3(5):260–268 CrossRefGoogle Scholar
  11. 11.
    Sun J, Vijayavenkataraman S, Liu H (2017) An overview of scaffold design and fabrication technology for engineered knee meniscus. Materials (Basel) 10(1):E29 CrossRefGoogle Scholar
  12. 12.
    Vaquero J, Forriol F (2016) Meniscus tear surgery and meniscus replacement. Muscles Ligaments Tendons J 6(1):71–89 CrossRefGoogle Scholar
  13. 13.
    Kaleka C, Debieux P, da Costa Astur D et al. (2014) Updates in biological therapies for knee injuries: menisci. Curr Rev Musculoskelet Med 7(3):247–255 CrossRefGoogle Scholar
  14. 14.
    Vrancken T, Buma P, van Tienen TG (2013) Synthetic meniscus replacement: a review. Int Orthop 37(2):291–299 CrossRefGoogle Scholar

Copyright information

© Società Italiana Ortopedici Traumatologi Ospedalieri d’Italia 2019

Authors and Affiliations

  • Matteo Olivieri
    • 1
    Email author
  • Diana Chicon Paez
    • 1
  • Luca Turelli
    • 1
  1. 1.S.O.C. Ortopedia, Dipartimento chirurgico, Ospedale S.M.A. FirenzeUSL Centro ToscanaFirenzeItalia

Personalised recommendations