Abstract
The aim of this study was to evaluate the potential of a biomimetic osteochondral scaffold for the treatment of osteochondritis dissecans (OCD). Twenty-seven consecutive patients, affected by knee OCD, were treated with the implantation of an acellular collagen-hydroxyapatite scaffold and prospectively evaluated at 4 years of follow-up. A significant improvement in all clinical scores was obtained at up to the final follow-up. This osteochondral scaffold is a valid option for knee OCD, showing a good and durable clinical outcome even for the treatment of large lesions.
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Si ringrazia Elettra Pignotti per l’analisi statistica.
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Gli autori Alessia Cavicchioli e Federica Balboni dichiarano di non aver alcun conflitto di interesse. L’autore Elizaveta Kon ha ricevuto un finanziamento dall’azienda Finceramica, Italia, Fidia, Italia, CartiHeal (2009) Ltd (Israele). L’autore Maurilio Marcacci ha ricevuto un finanziamento dall’azienda Finceramica, Faenza SpA (Italia). L’autore Giuseppe Filardo ha ricevuto un finanziamento dall’azienda Finceramica, Faenza SpA (Italia), Fidia Farmaceutici Spa (Italia), CartiHeal (2009) Ltd (Israele).
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Tutte le procedure descritte nello studio e che hanno coinvolto esseri umani sono state attuate in conformità alle norme etiche stabilite dalla dichiarazione di Helsinki del 1975 e successive modifiche. Il consenso informato è stato ottenuto da tutti i pazienti inclusi nello studio.
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Cavicchioli, A., Kon, E., Filardo, G. et al. Trattamento dell’osteocondrite dissecante del ginocchio con scaffold osteocondrale biomimetico. LO SCALPELLO 30, 121–126 (2016). https://doi.org/10.1007/s11639-016-0159-7
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DOI: https://doi.org/10.1007/s11639-016-0159-7