, Volume 30, Issue 1, pp 16–22 | Cite as

Profilassi antitromboembolica nel trauma scheletrico maggiore. Il punto di vista dell’ortopedico

  • Massimo MaricondaEmail author
  • Vincenzo Paolo Di Francia

Thromboprophylaxis in major skeletal trauma. The point of view of the orthopaedic surgeon


Deep Vein Thrombosis (DVT) and pulmonary embolism (\(\mathit{PE}\)) are important complications of major skeletal trauma and polytrauma that may occur after variable time following trauma and its treatment. A variety of risk factors including the complexity of fractures and associated injuries predispose these patient to DVT and PE. Hence, early and aggressive pharmacological prophylaxis must be carried out in this setting. Thromboprophylaxis needs to be balanced against the risk of haemorrhage. It could be useful to adopt a system to stratify the risk of thromboembolism in trauma patients and select the best option for an adequate prophylaxis. The available pharmacological agents include low-dose heparin, low molecular weight heparin, and factor Xa inhibitors. Mechanical prophylaxis methods include graduated compression stockings, pneumatic compression devices, and A-V foot pumps. Caval filters are an option in high-risk patients in whom pharmacological prophylaxis is contraindicated. All these prophylactic methods are reviewed.


Conflitto di interesse

Gli autori Massimo Mariconda e Vincenzo Paolo Di Francia dichiarano di non avere nessun conflitto di interesse.

Consenso informato e conformità agli standard etici

Tutte le procedure descritte nello studio e che hanno coinvolto esseri umani sono state attuate in conformità alle norme etiche stabilite dalla dichiarazione di Helsinki del 1975 e successive modifiche. Il consenso informato è stato ottenuto da tutti i pazienti inclusi nello studio.

Human and Animal Rights

L’articolo non contiene alcuno studio eseguito su esseri umani e su animali da parte degli autori.


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Copyright information

© Società Italiana Ortopedici Traumatologi Ospedalieri d’Italia 2016

Authors and Affiliations

  • Massimo Mariconda
    • 1
    Email author
  • Vincenzo Paolo Di Francia
    • 1
  1. 1.Clinica Ortopedica, Dipartimento di Sanità PubblicaUniversità degli Studi di Napoli Federico IINapoliItalia

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