Skip to main content
SpringerLink
Log in

SV40 large T antigen immortalization of rat hepatic stellate-like cells

  • Letter To The Editor
  • Scientific Reports
  • Published:
In Vitro Cellular & Developmental Biology - Animal Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Friedman, S. L. Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies—a review. N. Engl. J. Med. 328:1828–1835; 1993.

    Article  PubMed  CAS  Google Scholar 

  2. Greenwel, P.; Schwartz, M.; Rosas, M., et al. Characterization of fatstoring cell lines derived from normal and CCl4-cirrhotic livers. Lab. Invest. 65:644–653; 1991.

    PubMed  CAS  Google Scholar 

  3. Hu, Z.; Evarts, R. P.; Fujio, K., et al. Expression of hepatocyte growth factor and c-met genes during hepatic differentiation and liver development in the rat. Am. J. Pathol. 142:1823–1830; 1993.

    PubMed  CAS  Google Scholar 

  4. Kano, J.; Tokiwa, T.; Zhou, X. D., et al. Colonial growth and differentiation of epithelial cells derived from abattoir adult porcine livers. J. Gastroenterol. Hepatol. 13:S62–69; 1998.

    PubMed  Google Scholar 

  5. Kitamura, Y.; Tanigawa, T.; Katsumoto, T., et al. Cell growth and differentiation of a novel mouse Ito (fat-storing) cell line transformed by a temperature-sensitive mutant of simian virus 40. Hepatology 26:323–329; 1997.

    Article  PubMed  CAS  Google Scholar 

  6. Seglen, P. O. Preparation of isolated rat liver cells—a review. Methods Cell Biol. 13:29–83; 1976.

    Article  PubMed  CAS  Google Scholar 

  7. Senoo, H.; Hata, R. Isolation of perisinusoidal stellate cells (vitamin Astoring cells, fat-storing cells) of the liver. Connect. Tissue Res. 25:129–137; 1993.

    Google Scholar 

  8. Tokiwa, T.; Kano, J.; Kodama, M., et al. Multicellular rat hepatocyte aggregates formed on expanded polytetrafluoroethylene surface. Cytotechnology 25:137–144; 1997.

    Article  Google Scholar 

  9. Tokiwa, T.; Lipsky, M. M.; Smoot, D. T., et al. A method for transforming human liver epithelial cells by transfection using a plasmid containing SV40 early region gene. J. Tissue Cult. Methods 16:1–4; 1994.

    Article  Google Scholar 

  10. Yokoi, Y.; Namihisa, T.; Kuroda, H., et al. Immunocytochemical detection of desmin in fat-storing cells (Ito cells). Hepatology 4:709–714; 1984.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kohno Clinical Medicine Research Institute, 3-4-4 Kitashinagawa Shinagawa-ku, 140-0001, Tokyo, Japan

    Takayoshi Tokiwa

  2. Bionic Design, National Institute for Interdisciplinary Research, 1-1-4 Higashi Tsukuba, 305-8562, Ibaraki, Japan

    Takayoshi Tokiwa & Junko Kano

  3. Department of Pathology Institute of Basic Medical Sciences, University of Tsukuba, 1-1-1 Tennoudai Tsukuba, 305-8575, Ibaraki, Japan

    Takayoshi Tokiwa, Junko Kano & Masayuki Noguchi

  4. Third Department of Internal Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, 930-0194, Toyama, Japan

    Takayoshi Tokiwa, Yutaka Yata, Terumi Takahara & Akiharu Watanabe

  5. Department of Experimental Surgery and Bioengineering, National Children’s Medical Research Center, 3-35-31 Taishido Setagaya-ku, 154-8509, Tokyo, Japan

    Shin Enosawa & Seiichi Suzuki

Authors
  1. Takayoshi Tokiwa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yutaka Yata
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Terumi Takahara
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Akiharu Watanabe
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shin Enosawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Seiichi Suzuki
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Junko Kano
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Masayuki Noguchi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tokiwa, T., Yata, Y., Takahara, T. et al. SV40 large T antigen immortalization of rat hepatic stellate-like cells. In Vitro Cell.Dev.Biol.-Animal 35, 246–247 (1999). https://doi.org/10.1007/s11626-999-0067-8

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11626-999-0067-8

Keywords

Search

Navigation