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High salt inhibits both heparin-dependent and heparin-independent complexes of fibroblast growth factor and the receptor kinase

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References

  • Jang, J.-H.; Wang, F.; Kan, M. Heparan sulfate is required for interaction and activation of the epithelial cell fibroblast growth factor receptor-2IIIb with stromal-derived fibroblast growth factor-7. In Vitro Cell. Dev. Biol. Animal (in press); 1997.

  • Kan, M.; DiSorbo, D.; Hou, J., et al. High and low affinity binding of heparin-binding growth factor to a 130-kDa receptor correlates with stimulation and inhibition of growth of a differentiated human hepatoma cell. J. Biol. Chem. 263:11306–11313; 1988.

    PubMed  CAS  Google Scholar 

  • Kan, M.; Shi, E.; McKeehan, W. L. Identification and assay of heparin-binding (fibroblast) growth factor receptors. Methods Enzymol. 198:158–171; 1991.

    Article  PubMed  CAS  Google Scholar 

  • Kan, M.; Wang, F.; Kan, M., et al. Divalent cations and heparan sulfate cooperate to control assembly and activity of the fibroblast growth factor receptor complex. J. Biol. Chem. 271:26143–26148; 1996.

    Article  PubMed  CAS  Google Scholar 

  • Kan, M.; Wang, F.; Xu, J., et al. An essential heparin-binding domain in the fibroblast growth factor receptor kinase. Science 259:1918–1921; 1993.

    Article  PubMed  CAS  Google Scholar 

  • McKeehan, W. L.; Wang, F.; Kan, M. The heparan sulfate-fibroblast growth factor family: diversity of structure and function. Prog. Nucleic Acid Res. Mol. Biol. (in press); 1997.

  • Moscatelli, D. High and low affinity binding sites for basic fibroblast growth factor on cultured cells: absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells. J. Cell. Physiol. 131:123–130; 1987.

    Article  PubMed  CAS  Google Scholar 

  • Muenke, M.; Schell, U. Fibroblast-growth-factor receptor mutations in human skeletal disorders. Trends Genet. 11:308–313; 1995.

    Article  PubMed  CAS  Google Scholar 

  • Roghani, M.; Mansukhani, A.; Dell’Era, P., et al. Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding. J. Biol. Chem. 269:3976–3984; 1994.

    PubMed  CAS  Google Scholar 

  • Whitelock, J. M.; Murdock, A. D.; Iozzo, R. V., et al. The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase and heparanases. J. Biol. Chem. 271:10079–10086; 1996.

    Article  PubMed  CAS  Google Scholar 

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McKeehan, W.L., Wu, X., Jang, JH. et al. High salt inhibits both heparin-dependent and heparin-independent complexes of fibroblast growth factor and the receptor kinase. In Vitro Cell.Dev.Biol.-Animal 33, 727–730 (1997). https://doi.org/10.1007/s11626-997-0146-7

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  • DOI: https://doi.org/10.1007/s11626-997-0146-7

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