Abstract
Background
Smoking rates among people living with behavioral health conditions (BHC) range from 30 to 65% and are 2–4 times higher than rates found in the general population. Starting tobacco treatment during a hospital stay is effective for smoking cessation, but little is known regarding treatment response among inpatients with BHC.
Objective
This study pooled data across multiple clinical trials to determine the relative success in quitting among participants with BHC compared to other study participants.
Participants
Adults who smoke (≥ 18 years old) from five hospital-based smoking cessation randomized clinical trials.
Design
A retrospective analysis using data from the electronic health record to identify participants with primary diagnoses related to BHC. Recruitment and data analysis were conducted from 2011 to 2016. We used propensity score matching to pair patients with BHC to those with similar characteristics and logistic regression to determine differences between groups.
Measures
The main outcome was self-reported 30-day abstinence 6 months post-discharge.
Results
Of 6612 participants, 798 patients had a BHC-related primary diagnosis. The matched sample included 642 pairs. Nearly 1 in 3 reported using tobacco medications after hospitalization, with no significant difference between patients with and without BHC (29.3% vs. 31.5%; OR (95% CI) = 0.90 (0.71, 1.14), p = 0.40). Nearly 1 in 5 patients with BHC reported abstinence at 6 months; however, their odds of abstinence were 30% lower than among people without BHC (OR (95% CI) = 0.70 (0.53,0.92), p = 0.01).
Conclusion
When offered tobacco treatment, hospitalized patients with BHC were as likely as people without BHC to accept and engage in treatment. However, patients with BHC were less likely to report abstinence compared to those without BHC. Hospitals are a feasible and promising venue for tobacco treatment among inpatients with BHC. More studies are needed to identify treatment approaches that help people with BHC achieve long-term abstinence.
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References
Peacock A, et al. Global statistics on alcohol, tobacco and illicit drug use: 2017 status report. Addiction, 2018. 113(10):1905-1926.
Fornaro M, et al. The prevalence, odds, predictors, and management of tobacco use disorder or nicotine dependence among people with severe mental illness: Systematic review and meta-analysis. Neurosci Biobehav Rev, 2022. 132:289-303.
Han B, et al. Trends in Prevalence of cigarette smoking among US adults with major depression or substance use disorders, 2006-2019. JAMA, 2022. 327(16):1566-1576.
Smith PH, et al. Cigarette smoking among those with mental disorders in the US population: 2012–2013 update. Tobacco Control, 2020. 29(1):29.
Weinberger AH, et al. Cigarette smoking quit ratios among adults in the USA with cannabis use and cannabis use disorders, 2002-2016. Tob Control, 2020. 29(1):74-80.
de Leon J, Diaz FJ. A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors. Schizophr Res, 2005. 76(2-3):135-57.
Korchia T, et al. Recommendations of the treatment-resistant depression expert center network for promoting tobacco smoking cessation based on the results from the real-world FACE-TRD national cohort. Prog Neuropsychopharmacol Biol Psychiatry, 2022. 114:110479.
Tam J, Warner KE, Meza R. Smoking and the reduced life expectancy of individuals with serious mental illness. Am J Prev Med, 2016. 51(6):958-966.
Richter KP, et al. Commitment and capacity for providing evidence-based tobacco treatment in US drug treatment facilities. Subst Abus, 2017. 38(1):35-39.
Owens PL, McDermott KW, and H. KC. Inpatient stays involving mental and substance use disorders. Agency for Healthcare Research and Quality. 2016;2019.
Rigotti NA, et al. Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst Rev, 2012. 5(5):Cd001837.
Ylioja T, et al. Postdischarge smoking cessation in subgroups of hospitalized smokers: A latent class analysis. Subst Abus, 2017. 38(4):493-497.
Sanford, BT, et al. Tobacco treatment outcomes for hospital patients with and without mental health diagnoses. Front Psychiatry, 2022. 13: 853001.
Prochaska JJ, et al. Efficacy of initiating tobacco dependence treatment in inpatient psychiatry: a randomized controlled trial. Am J Public Health, 2014. 104(8): 1557-65.
Brown RA, et al. Sustained care smoking cessation intervention for individuals hospitalized for psychiatric disorders: The Helping HAND 3 randomized clinical trial. JAMA Psychiatry, 2021. 78(8): 839-847.
Riley WT, et al. Overview of the Consortium of Hospitals Advancing Research on Tobacco (CHART). Trials, 2012. 13:122.
Richter KP, et al. Warm handoff versus fax referral for linking hospitalized smokers to quitlines. Am J Prev Med, 2016. 51(4): 587-96.
Sherman SE, et al. Smoking-cessation interventions for urban hospital patients: a randomized comparative effectiveness trial. Am J Prev Med, 2016. 51(4):566-77.
Fellows JL, et al. Referring hospitalized smokers to outpatient quit services: a randomized trial. Am J Prev Med, 2016. 51(4):609-19.
Kathleen FH, et al. Web-based intervention for transitioning smokers from inpatient to outpatient care: an RCT. Am J Prev Med, 2016. 51(4):620-9.
Cummins SE, et al. Helping hospitalized smokers: a factorial RCT of nicotine patches and counseling. Am J Prev Med, 2016. 51(4):p 578-86.
Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. Mental Health Annual Report: 2015–2020. Use of Mental Health Services: National Client-Level Data (Appendix E). Rockville, MD: Substance Abuse and Mental Health Services Administration, 2022
Yuan Y, Yung YF, Stokes ME. Propensity score methods for causal inference with the PSMATCH Procedure. 2017.
Rigotti NA, et al. A post-discharge smoking-cessation intervention for hospital patients: Helping Hand 2 Randomized Clinical Trial. Am J Prev Med, 2016. 51(4):597-608.
Anthenelli RM, et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet, 2016. 387(10037):2507-20.
Cinciripini PM, et al. The effects of varenicline, bupropion, nicotine patch, and placebo on smoking cessation among smokers with major depression: A randomized clinical trial. Depress Anxiety, 2022. 39(5):429-440.
Falcaro M, et al. Time trends in access to smoking cessation support for people with depression or severe mental illness: a cohort study in English primary care. BMJ Open, 2021. 11(12):e048341.
Gilbody S, et al. Smoking cessation for people with severe mental illness (SCIMITAR+): a pragmatic randomised controlled trial. Lancet Psychiatry, 2019. 6(5):379-390.
Evins AE, Cather C, Daumit GL. Smoking cessation in people with serious mental illness. Lancet Psychiatry, 2019.
Marynak K, et al. Tobacco cessation interventions and smoke-free policies in mental health and substance abuse treatment facilities - United States, 2016. MMWR Morb Mortal Wkly Rep, 2018. 67(18):519-523.
American Psychiatric Association Presidential Report on the Assessment of Psychiatric Bed Needs in the United States. The Psychiatric Bed Crisis in the United States: Understanding the Problem and Moving Toward Solutions. Am J Psychiatry. 2022;179(8):586-588. https://doi.org/10.1176/appi.ajp.22179004.
Dohnke B, et al. Do hospital treatments represent a 'teachable moment' for quitting smoking? A study from a stage-theoretical perspective. Psychol Health, 2012. 27(11): 1291-307.
Acknowledgements
This study is part of the Consortium of Hospitals Advancing Research on Tobacco (CHART) initiative, jointly sponsored by the National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI), National Institute on Drug Abuse (NIDA) and the Office of Behavioral and Social Sciences (OBSSR) (U01 HL105232, PI: Kimber Richter, Ph.D., RC1HL099668, PI: Nancy Rigotti, Ph.D., U01HL105229, PI: Scott Sherman, MD, U01CA159533, PI: Shu-Hong Zhu, Ph.D., and U01DA031515, PI: Kathleen Harrington, MD). We acknowledge the work of all of our CHART colleagues who have contributed to the CHART initiative.
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Cruvinel, E., Mussulman, L., Scheuermann, T. et al. Hospital-Initiated Smoking Cessation Among Patients Admitted with Behavioral Health Conditions. J GEN INTERN MED (2024). https://doi.org/10.1007/s11606-024-08646-5
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DOI: https://doi.org/10.1007/s11606-024-08646-5