Who Orders Screening Mammograms in Older Women with Limited Life Expectancy?

INTRODUCTION

Breast cancer screening in older women with limited life expectancy may pose more harms than benefits but many of these women still receive screening mammograms.1, 2 Clinician recommendation is an important driver of screening.2 Previous surveys suggest that specialists are more likely than generalists to recommend screening mammograms for older women.3, 4 With the goal of better targeting future interventions, we examined the specialties of the clinicians who referred older women for mammograms in a nationally representative cohort and whether the specialties varied depending on the women’s estimated life expectancies. We then investigated whether the receipt of screening mammograms was linked with outpatient visits with different types of clinicians.

METHODS

Using data from the first wave of the National Health and Aging Trends Study (NHATS) in 2011 linked to Medicare claims, we identified women 65+ years old without history of breast cancer who were continuously enrolled in fee-for-service Medicare from 2010 to 2013. Medicare data in the 12 months prior to the 2011 NHATS interview were used to exclude patients with breast cancer history while data in the 24 months following the 2011 NHATS interview, defined as the study period, were used to assess receipt of screening. Screening mammograms were identified using claims data.5 Ten-year mortality risks were predicted from a validated index6 using survey data (excluding n = 355 with missing information); predicted mortality was then used to categorize women as having < 10-year versus > 10-year median life expectancies.

First, we examined the specialties of the referring clinicians associated with a patient’s screening mammogram on Medicare claim. We compared the distribution of the referring clinicians’ specialties among women with < 10-year-predicted life expectancy and among women with > 10-year-predicted life expectancy using the chi-square test. Second, we used a logistic regression model to assess the association of different types of outpatient visits with breast cancer screening. The dependent variable was receipt of screening mammography. Independent variables included whether the patient had a primary care provider, a gynecology visit, and the total number of outpatient visits with all other types of clinicians, all within the 12 months prior to the study period. The model controlled for predicted life expectancy (< 10 years versus > 10 years), age, and race. We tested for interaction between predicted life expectancy and each of the three independent variables.

RESULTS

Among the 2041 women in our cohort, 48.0% received at least one screening mammogram during the study period, with screening rate of 60.2% among women with > 10-year-predicted life expectancy and 27.0% among women with < 10-year-predicted life expectancy (Table 1). Among the women who received screening, specialty of the referring clinician for the screening mammogram was available for 794 (94.2%) women. For both life expectancy groups, the most common clinician specialties associated with screening mammogram referrals were internal medicine, followed by family medicine, and obstetrics/gynecology (Table 1), with no significant difference in the distribution of clinician specialties between the two groups (p = 0.30).

Table 1 Participant Characteristics, Screening Mammogram Rates, and Clinician Specialties Associated with Screening Mammogram Referrals Among the 2041 Women Included in the Study

In the adjusted regression model, we found that visiting a gynecologist was associated with increased odds of receiving screening mammograms (odds ratio [OR] 2.28, 95% confidence interval [CI] 1.48, 3.51, p < 0.001) and this association did not significantly differ by the patient’s predicted life expectancy (interaction term p = 0.25). We found having a primary care provider (PCP) was also associated with increased odds of receiving screening mammograms but the effect differed by the patients’ predicted life expectancies (interaction term p = 0.04). In women with > 10-year-predicted life expectancy, having a PCP was associated with OR 3.27 of receiving screening mammograms (95% CI 2.31, 4.64) whereas in women with < 10-year-predicted life expectancy, this effect was smaller with OR 1.84 (95% CI 1.13, 3.00). The number of other types of outpatient visits was not independently associated with receipt of screening mammograms (OR 1.01 per visit, 95% CI 0.99, 1.04, p = 0.32).

DISCUSSION

In a national representative cohort of older women, we found that PCPs and gynecologists were associated with most of the screening mammogram referrals and, correspondingly, having a PCP and visiting a gynecologist were both independently associated with higher screening rates. Interventions that target both types of clinicians are likely to be more effective than those targeting primary care providers alone. Interestingly, the effect of having a PCP differed by life expectancy and may suggest that PCPs are, to some extent, taking into account the patients’ life expectancies in their breast cancer screening practices.

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Funding/Support

Dr. Schoenborn was financially supported by a Cancer Control Career Development Award from the American Cancer Society (CCCDA-16-002-01) and a career development award from the National Institute on Aging (K76AG059984). Dr. Boyd was financially supported by 1K24AG056578 from the National Institute on Aging.

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Dr. Schoenborn had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Schoenborn, Huang, Boyd, Pollack.

Data analysis and interpretation: Schoenborn, Huang, Boyd, Nowak, Pollack.

Preparation and review of the manuscript: Schoenborn, Huang, Boyd, Nowak, Pollack

Corresponding author

Correspondence to Nancy L. Schoenborn MD, MHS.

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Conflict of Interest

The authors declare that they do not have a conflict of interest. Dr. Pollack has stock ownership in Gilead Pharmaceuticals. We do not believe this has resulted in any conflict with the design, methodology, or results presented in this manuscript. Dr. Cynthia Boyd received a small payment from UptoDate for having co-authored a chapter on Multimorbidity; we do not believe this has resulted in any conflict with the design, methodology, or results presented in this manuscript.

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Schoenborn, N.L., Huang, J., Boyd, C.M. et al. Who Orders Screening Mammograms in Older Women with Limited Life Expectancy?. J GEN INTERN MED 34, 2720–2722 (2019). https://doi.org/10.1007/s11606-019-05044-0

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