Journal of General Internal Medicine

, Volume 34, Issue 2, pp 281–284 | Cite as

Rising Mortality Rate of Cervical Cancer in Younger Women in Urban China

  • Min Wei
  • Wei Zhou
  • Yongyi Bi
  • Hong Wang
  • Yu Liu
  • Zhi-Jiang ZhangEmail author
Original Research



In recent decades, much effort has been made in China to reduce the burden of cervical cancer.


Our study’s purpose was to examine trends of cervical cancer mortality in each 5-year age group for urban and rural Chinese women, respectively.


Retrospective analysis of cervical cancer mortality from 1987 to 2015 from the World Health Organization Cancer Mortality Database and China Health Statistical Yearbooks.


Chinese women.

Main Measures

Trends were examined using annual percent change (APC) and average annual percent change (AAPC) via Joinpoint regression models for each 5-year age group in urban and rural areas, respectively.


In urban China, mortality rate of cervical cancer increased significantly among urban women aged 25–54 years (AAPC 2.12~5.49%), in contrast to a decline trend among urban women older than 60 years (AAPC − 3.61~− 5.35%). In rural China, cervical cancer rates declined in all age groups, but the magnitude was smaller in women aged 30–54 years (AAPC − 0.59~− 2.20%) compared to women older than 55 years (AAPC − 3.06~− 4.33%).


Mortality rate of cervical cancer is rising at an alarming rate in younger women in urban China. Timely intervention is required for these vulnerable populations.


cervical cancer disparity age-specific mortality trend 


Authors’ Contributions

Min Wei drafted the manuscript; Wei Zhou drafted the manuscript and collected and analyzed data; Yongyi Bi, Hong Wang, and Yu Liu edited and commented the manuscript; and Zhi-Jiang Zhang concepted the study, supervise the research, and edited the manuscript.


The work was financially supported by the National Natural Science Foundation of China (grant number 81641123) and the Fundamental Research Funds for the Central Universities (grant number 2042017kf0193).

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they do not have a conflict of interest.

Supplementary material

11606_2018_4732_MOESM1_ESM.docx (18 kb)
ESM 1 (DOCX 17 kb)


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Copyright information

© Society of General Internal Medicine 2018

Authors and Affiliations

  • Min Wei
    • 1
    • 2
  • Wei Zhou
    • 2
  • Yongyi Bi
    • 2
  • Hong Wang
    • 2
  • Yu Liu
    • 3
  • Zhi-Jiang Zhang
    • 2
    Email author
  1. 1.Department of Obstetrics and GynecologyRenmin Hospital of Wuhan UniversityWuhanChina
  2. 2.Department of Preventive Medicine, School of Health Sciences Wuhan UniversityWuhanChina
  3. 3.Department of Statistics and Management, School of ManagementWuhan Institute of TechnologyWuhanChina

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