Journal of General Internal Medicine

, Volume 33, Issue 8, pp 1218–1220 | Cite as

Acetaminophen or Tylenol? A Retrospective Analysis of Medication Digital Communication Practices

  • David OuyangEmail author
  • Rebecca Tisdale
  • Euan Ashley
  • Jeffrey Chi
  • Jonathan H. Chen
Concise Research Reports


Prescribing of brand name drugs when generic alternatives exist has been linked to decreased patient adherence and worse health outcomes.1 Furthermore, failure to substitute brand name for generic drugs results in billions of dollars in estimated excess costs to individual patients and the US health system yearly.2 Using drugs’ trade names rather than generic names in clinical practice has been shown to increase usage of these brand name drugs over their generic equivalents, even when pharmacy substitution is available.3 American medical schools have therefore included policies supporting use of nonproprietary drug names in the clinical setting as part of a range of interventions to promote generic prescribing and limit industry influence on medical students and trainees.4

To what extent physicians and other healthcare providers continue to use trade names versus generic names in clinical communication is difficult to measure; however, text pages represent a contemporaneous...


Pharmacoeconomics physician sentiment provider communication choosing wisely hidden curriculum 



The authors would like to thank Dr. Paul Cheng and Dr. Jody Shen for constructive criticism of the manuscript.

Author contributions

Dr. Ouyang had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Ouyang.

Acquisition of data: Ouyang, Chi, and Chen.

Analysis and interpretation of data: Ouyang, Tisdale, Ashley, Chi, and Chen.

Drafting of the manuscript: Ouyang and Tisdale.

Critical revision of the manuscript for important intellectual content: Ouyang, Tisdale, Ashley, Chi, and Chen.

Statistical analysis: Ouyang, Tisdale, and Chen.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they do not have a conflict of interest.


  1. 1.
    Gagne JJ, Choudhry NK, Kesselheim AS, Polinski JM, Hutchins D, Matlin OS, Brennan TA, Avorn J, Shrank WH. Comparative effectiveness of generic and brand-name statins on patient outcomes: a cohort study. Ann Intern Med 2014;161(6):400–407. doi: CrossRefPubMedGoogle Scholar
  2. 2.
    Kale MS, Bishop TF, Federman AD, Keyhani S. “Top 5” lists top $5 billion (Research Letter). Arch Intern Med 2011;171(20):1856–1858. doi: Scholar
  3. 3.
    Mott DA, Cline RR. Exploring generic drug use behavior: the role of prescribers and pharmacists in the opportunity for generic drug use and generic substitution. Med Care 2002;40(8):662–674. doi: CrossRefPubMedGoogle Scholar
  4. 4.
    Obley AJ, Iossi KA, Humphrey LL. Teaching Wisely. J Grad Med Educ 2014;6(3):587–588. doi: Scholar
  5. 5.
    AAMC. U.S. Medical School Applications and Matriculants by School, State of Legal Residence, and Sex, 2017–2018. Available:
  6. 6.
    Choudhry NK, Denberg TD, Qaseem A. Improving adherence to therapy and clinical outcomes while containing costs: opportunities from the greater use of generic medications: best practice advice from the Clinical Guidelines Committee of the American College of Physicians. Ann Intern Med 2016;164:41–49. CrossRefPubMedGoogle Scholar

Copyright information

© Society of General Internal Medicine 2018

Authors and Affiliations

  • David Ouyang
    • 1
    Email author
  • Rebecca Tisdale
    • 2
  • Euan Ashley
    • 1
  • Jeffrey Chi
    • 2
  • Jonathan H. Chen
    • 2
  1. 1.Department of Internal Medicine, Division of Cardiovascular Medicine Stanford University School of MedicineStanfordUSA
  2. 2.Department of Internal Medicine, Division of Hospital MedicineStanford University School of MedicineStanfordUSA

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