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One Anastomosis Gastric Bypass Versus Sleeve Gastrectomy for Obesity: a Systemic Review and Meta-analysis

  • Review Article
  • Published:
Journal of Gastrointestinal Surgery

Abstract

Background

A long-lasting and efficient method of managing obesity and therapeutic associated comorbidities is bariatric surgery. However, a debated comparison between one-anastomosis gastric bypass (OAGB) and sleeve gastrectomy is still essential (SG). The goal of this study is to evaluate outcomes using RCT and NRCT from 2015 to 2022.

Methods

By contrasting the OAGB and SG for bariatric surgery from January 2015 to September 2022, an RCT and NRCT were prospectively gathered using the PubMed, Cochrane Library, and MEDLINE databases of published research. This meta-statistical analysis was carried out in RevMan 5.4, and the best effect model was selected based on heterogeneity.

Results

Twelve retrospective studies describing 6344 patients (3725 OAGB and 2619 SG) satisfied the inclusion criteria. A statistically significant result was in %EWL first year (MD = 8.03, 95% CI: 4.54–11.52, P < 0.05), second year (MD = 8.94, 95% CI: 2.95–14.94, P < 0.05), third year (MD = 8.93, 95% CI: 5.75–12.10, P < 0.05), fourth year (MD = 15.09, 95% CI:0.87–29.31, P < 0.05), and fifth year (MD = 14.25, 95% CI: 5.34, P < 0.05). OAGB was associated with a lower rate of remission in dyslipidemia, hypertension, diabetes mellitus, and hemorrhage. However, OAGB increased the incidence of GERD and leakage.

Conclusions

In terms of weight loss and comorbidity remission, OAGB is more effective than SG, although postoperative consequences are rather comparable between the two methods.

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Data Availability

The data presented in this study are available upon reasonable request.

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Acknowledgements

We thank Northern Jiangsu People’s Hospital for helpful statistical advice.

Funding

The National Natural Science Foundation of China (No. 81972269) and Key Laboratory of Basic and Clinical Transformation of Digestive and Metabolic Diseases, Yangzhou, China (YZ2020159).

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Authors and Affiliations

  1. Medical College of Yangzhou University, Yangzhou, People’s Republic of China

    Muhammad Ali, Yang Wang, Jin Ji, Wei Wang & Daorong Wang

  2. Department of General Surgery, General Surgery Institute of Yangzhou, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, 98 Nantong West Road, Yangzhou, Jiangsu, 225001, People’s Republic of China

    Muhammad Ali, Yang Wang, Jin Ji, Wei Wang & Daorong Wang

  3. Yangzhou Key Laboratory of Basic and Clinical Transformation of Digestive and Metabolic Diseases, Yangzhou, Jiangsu, 225001, People’s Republic of China

    Muhammad Ali, Yang Wang, Jin Ji & Daorong Wang

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Contributions

Muhammad Ali wrote the manuscript and participated in data analysis, Yang Wang in the manuscript selection and study design, and Jin Ji and Wei Wang helped in data collection. Final manuscript review by Daorong Wang.

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Correspondence to Daorong Wang.

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Ali, M., Wang, Y., Ji, J. et al. One Anastomosis Gastric Bypass Versus Sleeve Gastrectomy for Obesity: a Systemic Review and Meta-analysis. J Gastrointest Surg 27, 2226–2244 (2023). https://doi.org/10.1007/s11605-023-05782-x

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