References
Sun L, Guo C, Yuan H, et al. Overexpression of carboxypeptidase A4 (CPA4) is associated with poor prognosis in patients with gastric cancer. Am J Transl Res. 2016 15;8(11):5071–5075.
Pan H, Pan J, Ji L, et al. Carboxypeptidase A4 promotes cell growth via activating STAT3 and ERK signaling pathways and predicts a poor prognosis in colorectal cancer. Int J Biol Macromol. 2019 1;138:125-134. doi: https://doi.org/10.1016/j.ijbiomac.2019.07.028
Hareendran S, Yang X, Sharma VK, et al. Carboxypeptidase E and its splice variants: Key regulators of growth and metastasis in multiple cancer types. Cancer Lett. 2022 1;548:215882. doi: https://doi.org/10.1016/j.canlet.2022.215882
Bouchal P, Dvořáková M, Roumeliotis T, et al. Combined Proteomics and Transcriptomics Identifies Carboxypeptidase B1 and Nuclear Factor κB (NF-κB) Associated Proteins as Putative Biomarkers of Metastasis in Low Grade Breast Cancer. Mol Cell Proteomics. 2015;14(7):1814-30. doi: https://doi.org/10.1074/mcp.M114.041335
Robin X, Turck N, Hainard A, Tiberti N, Lisacek F, et al. pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinformatics. 2011 12:77. doi: https://doi.org/10.1186/1471-2105-12-77
McDaniel LD, Conkrite KL, Chang X, et al. Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma. PLoS Genet. 2017 18;13(5):e1006787. doi: https://doi.org/10.1371/journal.pgen.1006787
Funding
This study was supported by the Tackle Key Problems in Medicine of Henan Province (201003124, LHGJ20200188).
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Concept and design: SL. Acquisition, analysis, or interpretation of data: SL, WY, LP, and FM. Drafting of the manuscript: SL and YL. Critical revision of the manuscript for important intellectual content: ZZ and YH. Administrative, technical, or material support, and study supervision: YH. All authors contributed to the article and approved the submitted version.
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All data used in this research were obtained from TCGA, a publicly available cancer database, so according to Swedish law, this study was exempt from the need to obtain signed informed consent.
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Lu, S., Yang, W., Liu, Y. et al. Diagnostic and Prognostic Value of CPZ in Patients with Gastric Cancer by Integrated Analysis. J Gastrointest Surg 27, 1253–1255 (2023). https://doi.org/10.1007/s11605-023-05648-2
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DOI: https://doi.org/10.1007/s11605-023-05648-2