Abstract
Introduction
Hydatidosis is a chronic disease that is endemic and prevalent in certain regions of the world. Surgical treatment is the best option, although its main problem is that there is a high rate of recurrence. The objective of the present study was to assess its therapeutic management and the factors related to its postoperative morbidity and relapse.
Material and Methods
A descriptive and retrospective study was made of 238 patients with hepatic hydatidosis operated from January 2006 to December 2017 at our center. An analysis was made of the variables associated with postoperative morbidity and relapse, and of the temporal pattern of that relapse.
Results
Out of 238 patients, radical surgery was performed in 132 (55.5%) and partial cystectomy in 106 of them (44.3%). The postoperative morbidity was 42% (100/238) and the relapse rate was 7.2% (17/238). The factors associated with greater postoperative morbidity were partial cystectomy (OR, 2.83 (1.47–5.43); p = 0.002), ≥ 2 cysts (OR, 3.22 (1.51–6.86); p = 0.002), and biliary fistula (OR, 4.34 (2.11–8.91); p < 0.0001); and those associated with higher relapse rate were history of hydatidosis (OR, 4.98 (1.76–14.11); p = 0.003) and ≥ 2 cysts (OR, 3.23 (1.14–9.11); p = 0.027). The first relapses appeared after 14 months, with the greatest incidence between 14 and 36 months.
Conclusions
The surgical procedure applied is associated with morbidity but not with that of relapse. The observed relapse pattern demonstrates the need to maintain long-term follow-up, but with no follow-up being necessary in the first year. Broader multicenter and prospective studies are needed to establish more precise recommendations.
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Isabel Jaén-Torrejimeno contributed to the acquisition, analysis, and interpretation of data for the work, and drafting of the work. She gives her final approval of the version to be published and agrees to be accountable for all aspects of the work.
Diego López-Guerra contributed to the acquisition and analysis of data for the work and revised it critically. He gives his final approval of the version to be published and agrees to be accountable for all aspects of the work.
Aranzazu Prada-Villaverde contributed to the acquisition of data for the work and revised it critically. She gives her final approval of the version to be published and agrees to be accountable for all aspects of the work.
Gerardo Blanco-Fernández contributed to the conception and design of the work; acquisition, analysis, and interpretation of data for the work; and drafting of the work. He gives his final approval of the version to be published and agrees to be accountable for all aspects of the work.
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Jaén-Torrejimeno, I., López-Guerra, D., Prada-Villaverde, A. et al. Pattern of Relapse in Hepatic Hydatidosis: Analysis of 238 Cases in a Single Hospital. J Gastrointest Surg 24, 361–367 (2020). https://doi.org/10.1007/s11605-019-04163-7
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DOI: https://doi.org/10.1007/s11605-019-04163-7