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Risk Factors for Weight Loss 1 Year After Esophagectomy and Gastric Pull-up for Esophageal Cancer

  • Original Article
  • Published:
Journal of Gastrointestinal Surgery

Abstract

Background

Loss of body weight is regarded as a marker of malnutrition after esophagectomy. This study investigated changes in body weight and risk factors for weight loss after esophagectomy for esophageal cancer.

Methods

We retrospectively reviewed records of 181 patients who underwent esophagectomy and gastric pull-up from 2012 to June 2016. Patients with operative mortality and recurrences were excluded. Percent change in body weight was defined as change in body weight (%) = (1-year body weight − preoperative body weight) × 100/preoperative body weight.

Results

Mean age of patients was 62.98 ± 8.23 years with 164 men (90.6%). Mean preoperative body weight was 63.12 ± 9.42 kg, and body weight at 1 year was 56.04 ± 8.59 kg. Mean change in body weight was − 10.95 ± 7.50%, and 98 (54.1%) patients showed weight loss more than 10% compared to initial body weight. Univariable analysis showed that initial body weight, narrow gastric tube, thoracotomy, laparotomy, and postoperative vocal cord palsy (VCP) were related to more than 10% weight loss. Multivariable analysis showed that initial body weight (odds ratio [OR] = 1.041, p = 0.031) and postoperative VCP (OR = 2.772, p = 0.025) were adverse risk factors for weight loss 1 year after esophagectomy, whereas conduit type, route of reconstruction, postoperative complications, anastomotic complications, minimally invasive esophagectomy, and adjuvant therapy were not.

Conclusions

Initial body weight and postoperative VCP were related to weight loss. Patients with VCP need additional nutritional monitoring and support.

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Authors and Affiliations

  1. Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea

    Seong Yong Park, Dae Joon Kim, Jee Won Suh & Go Eun Byun

Authors
  1. Seong Yong Park
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  2. Dae Joon Kim
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  3. Jee Won Suh
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  4. Go Eun Byun
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Contributions

(I) Conception and design: Seong Yong Park.

(II) Administrative support: Seong Yong Park.

(III) Provision of study materials or patients: All authors.

(IV) Collection and assembly of data: Seong Yong Park, Go Eun Byun, Jee Won Suh.

(V) Data analysis and interpretation: Seong Yong Park, Dae Joon Kim.

(VI) Manuscript writing: Seong Yong Park.

(VII) Final approval of manuscript: All authors.

Corresponding author

Correspondence to Dae Joon Kim.

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No authors have financial disclosures or conflicts of interest.

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Park, S., Kim, D., Suh, J. et al. Risk Factors for Weight Loss 1 Year After Esophagectomy and Gastric Pull-up for Esophageal Cancer. J Gastrointest Surg 22, 1137–1143 (2018). https://doi.org/10.1007/s11605-018-3749-2

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  • DOI: https://doi.org/10.1007/s11605-018-3749-2

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